1q1v

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (18:15, 29 May 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Structure of the Oncoprotein DEK: a putative DNA-binding Domain Related to the Winged Helix Motif==
==Structure of the Oncoprotein DEK: a putative DNA-binding Domain Related to the Winged Helix Motif==
-
<StructureSection load='1q1v' size='340' side='right' caption='[[1q1v]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
+
<StructureSection load='1q1v' size='340' side='right'caption='[[1q1v]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1q1v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q1V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Q1V FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1q1v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q1V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q1V FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dek ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1q1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q1v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1q1v RCSB], [http://www.ebi.ac.uk/pdbsum/1q1v PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q1v OCA], [https://pdbe.org/1q1v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q1v RCSB], [https://www.ebi.ac.uk/pdbsum/1q1v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q1v ProSAT]</span></td></tr>
-
<table>
+
</table>
== Disease ==
== Disease ==
-
[[http://www.uniprot.org/uniprot/DEK_HUMAN DEK_HUMAN]] Note=A chromosomal aberration involving DEK is found in a subset of acute myeloid leukemia (AML); also known as acute non-lymphocytic leukemia. Translocation t(6;9)(p23;q34) with NUP214/CAN. It results in the formation of a DEK-CAN fusion gene.
+
[https://www.uniprot.org/uniprot/DEK_HUMAN DEK_HUMAN] Note=A chromosomal aberration involving DEK is found in a subset of acute myeloid leukemia (AML); also known as acute non-lymphocytic leukemia. Translocation t(6;9)(p23;q34) with NUP214/CAN. It results in the formation of a DEK-CAN fusion gene.
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/DEK_HUMAN DEK_HUMAN]] Involved in chromatin organization.<ref>PMID:17524367</ref>
+
[https://www.uniprot.org/uniprot/DEK_HUMAN DEK_HUMAN] Involved in chromatin organization.<ref>PMID:17524367</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q1/1q1v_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q1/1q1v_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
-
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q1v ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 28: Line 29:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 1q1v" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
Line 33: Line 35:
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Devany, M.]]
+
[[Category: Large Structures]]
-
[[Category: Kotharu, N P.]]
+
[[Category: Devany M]]
-
[[Category: Matsuo, H.]]
+
[[Category: Kotharu NP]]
-
[[Category: Dna binding protein]]
+
[[Category: Matsuo H]]
-
[[Category: Winged-helix motif]]
+

Current revision

Structure of the Oncoprotein DEK: a putative DNA-binding Domain Related to the Winged Helix Motif

PDB ID 1q1v

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1q1v"
Personal tools