1q1v

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==Structure of the Oncoprotein DEK: a putative DNA-binding Domain Related to the Winged Helix Motif==
==Structure of the Oncoprotein DEK: a putative DNA-binding Domain Related to the Winged Helix Motif==
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<StructureSection load='1q1v' size='340' side='right'caption='[[1q1v]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='1q1v' size='340' side='right'caption='[[1q1v]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1q1v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q1V OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1Q1V FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1q1v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q1V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q1V FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dek ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1q1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q1v OCA], [http://pdbe.org/1q1v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1q1v RCSB], [http://www.ebi.ac.uk/pdbsum/1q1v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1q1v ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q1v OCA], [https://pdbe.org/1q1v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q1v RCSB], [https://www.ebi.ac.uk/pdbsum/1q1v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q1v ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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[[http://www.uniprot.org/uniprot/DEK_HUMAN DEK_HUMAN]] Note=A chromosomal aberration involving DEK is found in a subset of acute myeloid leukemia (AML); also known as acute non-lymphocytic leukemia. Translocation t(6;9)(p23;q34) with NUP214/CAN. It results in the formation of a DEK-CAN fusion gene.
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[https://www.uniprot.org/uniprot/DEK_HUMAN DEK_HUMAN] Note=A chromosomal aberration involving DEK is found in a subset of acute myeloid leukemia (AML); also known as acute non-lymphocytic leukemia. Translocation t(6;9)(p23;q34) with NUP214/CAN. It results in the formation of a DEK-CAN fusion gene.
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DEK_HUMAN DEK_HUMAN]] Involved in chromatin organization.<ref>PMID:17524367</ref>
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[https://www.uniprot.org/uniprot/DEK_HUMAN DEK_HUMAN] Involved in chromatin organization.<ref>PMID:17524367</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Devany, M]]
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[[Category: Devany M]]
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[[Category: Kotharu, N P]]
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[[Category: Kotharu NP]]
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[[Category: Matsuo, H]]
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[[Category: Matsuo H]]
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[[Category: Dna binding protein]]
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[[Category: Winged-helix motif]]
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Current revision

Structure of the Oncoprotein DEK: a putative DNA-binding Domain Related to the Winged Helix Motif

PDB ID 1q1v

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