2div

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{{Seed}}
 
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[[Image:2div.png|left|200px]]
 
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<!--
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==Solution structure of the RRM domain of TRNA selenocysteine associated protein==
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The line below this paragraph, containing "STRUCTURE_2div", creates the "Structure Box" on the page.
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<StructureSection load='2div' size='340' side='right'caption='[[2div]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2div]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DIV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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-->
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2div FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2div OCA], [https://pdbe.org/2div PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2div RCSB], [https://www.ebi.ac.uk/pdbsum/2div PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2div ProSAT], [https://www.topsan.org/Proteins/RSGI/2div TOPSAN]</span></td></tr>
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{{STRUCTURE_2div| PDB=2div | SCENE= }}
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</table>
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== Function ==
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===Solution structure of the RRM domain of TRNA selenocysteine associated protein===
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[https://www.uniprot.org/uniprot/TSAP1_HUMAN TSAP1_HUMAN] Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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2DIV is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DIV OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/di/2div_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2div ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Dang, W.]]
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[[Category: Large Structures]]
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[[Category: Inoue, M.]]
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[[Category: Dang W]]
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[[Category: Kigawa, T.]]
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[[Category: Inoue M]]
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[[Category: Muto, Y.]]
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[[Category: Kigawa T]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Muto Y]]
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[[Category: Shirouzu, M.]]
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[[Category: Shirouzu M]]
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[[Category: Terada, T.]]
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[[Category: Terada T]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama S]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nmr]]
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[[Category: Nppsfa]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rna binding protein]]
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[[Category: Rrm domain]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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[[Category: Trna selenocysteine associated protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 13 10:33:06 2009''
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Current revision

Solution structure of the RRM domain of TRNA selenocysteine associated protein

PDB ID 2div

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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