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2djq

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==The solution structure of the first SH3 domain of mouse SH3 domain containing ring finger 2==
==The solution structure of the first SH3 domain of mouse SH3 domain containing ring finger 2==
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<StructureSection load='2djq' size='340' side='right' caption='[[2djq]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2djq' size='340' side='right'caption='[[2djq]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2djq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DJQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DJQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2djq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DJQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DJQ FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Sh3rf2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2djq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2djq OCA], [http://pdbe.org/2djq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2djq RCSB], [http://www.ebi.ac.uk/pdbsum/2djq PDBsum], [http://www.topsan.org/Proteins/RSGI/2djq TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2djq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2djq OCA], [https://pdbe.org/2djq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2djq RCSB], [https://www.ebi.ac.uk/pdbsum/2djq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2djq ProSAT], [https://www.topsan.org/Proteins/RSGI/2djq TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SH3R2_MOUSE SH3R2_MOUSE]] Inhibits PPP1CA phosphatase activity. May be a E3 ubiquitin-protein ligase (Potential). May play a role in cardiac function (By similarity).
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[https://www.uniprot.org/uniprot/SH3R2_MOUSE SH3R2_MOUSE] Inhibits PPP1CA phosphatase activity. May be a E3 ubiquitin-protein ligase (Potential). May play a role in cardiac function (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dj/2djq_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dj/2djq_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Inoue, M]]
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[[Category: Mus musculus]]
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[[Category: Kigawa, T]]
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[[Category: Inoue M]]
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[[Category: Koshiba, S]]
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[[Category: Kigawa T]]
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[[Category: Structural genomic]]
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[[Category: Koshiba S]]
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[[Category: Sasagawa, A]]
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[[Category: Sasagawa A]]
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[[Category: Tochio, N]]
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[[Category: Tochio N]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: Clone:4831401o22]]
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[[Category: Mus musculus 0 day neonate head cdna]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Riken full-length enriched library]]
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[[Category: Rsgi]]
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[[Category: Sh3 domain]]
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[[Category: Unknown function]]
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Current revision

The solution structure of the first SH3 domain of mouse SH3 domain containing ring finger 2

PDB ID 2djq

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