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2dk7

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==Solution structure of WW domain in transcription elongation regulator 1==
==Solution structure of WW domain in transcription elongation regulator 1==
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<StructureSection load='2dk7' size='340' side='right' caption='[[2dk7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2dk7' size='340' side='right'caption='[[2dk7]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dk7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DK7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DK7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dk7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DK7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DK7 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TCERG1, CA150, TAF2S ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dk7 OCA], [http://pdbe.org/2dk7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dk7 RCSB], [http://www.ebi.ac.uk/pdbsum/2dk7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dk7 ProSAT], [http://www.topsan.org/Proteins/RSGI/2dk7 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dk7 OCA], [https://pdbe.org/2dk7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dk7 RCSB], [https://www.ebi.ac.uk/pdbsum/2dk7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dk7 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dk7 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TCRG1_HUMAN TCRG1_HUMAN]] Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.<ref>PMID:9315662</ref> <ref>PMID:11604498</ref>
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[https://www.uniprot.org/uniprot/TCRG1_HUMAN TCRG1_HUMAN] Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.<ref>PMID:9315662</ref> <ref>PMID:11604498</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: He, F]]
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[[Category: Large Structures]]
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[[Category: Inoue, M]]
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[[Category: He F]]
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[[Category: Kigawa, T]]
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[[Category: Inoue M]]
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[[Category: Muto, Y]]
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[[Category: Kigawa T]]
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[[Category: Structural genomic]]
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[[Category: Muto Y]]
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[[Category: Shirouzu, M]]
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[[Category: Shirouzu M]]
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[[Category: Terada, T]]
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[[Category: Terada T]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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[[Category: Transcription]]
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[[Category: Transcription elongation regulator 1]]
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[[Category: Ww domain]]
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Current revision

Solution structure of WW domain in transcription elongation regulator 1

PDB ID 2dk7

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