2dm8

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{{Seed}}
 
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[[Image:2dm8.png|left|200px]]
 
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==Solution structure of the eighth PDZ domain of human InaD-like protein==
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The line below this paragraph, containing "STRUCTURE_2dm8", creates the "Structure Box" on the page.
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<StructureSection load='2dm8' size='340' side='right'caption='[[2dm8]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2dm8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DM8 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dm8 OCA], [https://pdbe.org/2dm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dm8 RCSB], [https://www.ebi.ac.uk/pdbsum/2dm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dm8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dm8 TOPSAN]</span></td></tr>
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{{STRUCTURE_2dm8| PDB=2dm8 | SCENE= }}
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</table>
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== Function ==
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===Solution structure of the eighth PDZ domain of human InaD-like protein===
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[https://www.uniprot.org/uniprot/INADL_HUMAN INADL_HUMAN] Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons.<ref>PMID:11927608</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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2DM8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DM8 OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dm/2dm8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dm8 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Hayashi, F.]]
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[[Category: Hayashi F]]
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[[Category: Inoue, K.]]
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[[Category: Inoue K]]
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[[Category: Nagashima, T.]]
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[[Category: Nagashima T]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S.]]
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[[Category: Hinadl]]
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[[Category: Inad-like protein]]
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[[Category: Inadl]]
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[[Category: Inadl protein]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Pals1-associated tight junction protein]]
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[[Category: Patj]]
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[[Category: Pdz domain]]
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[[Category: Protein associated to tight junction]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 29 06:26:47 2008''
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Current revision

Solution structure of the eighth PDZ domain of human InaD-like protein

PDB ID 2dm8

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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