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2dms

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==Solution structure of the homeobox domain of Homeobox protein OTX2==
==Solution structure of the homeobox domain of Homeobox protein OTX2==
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<StructureSection load='2dms' size='340' side='right' caption='[[2dms]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2dms' size='340' side='right'caption='[[2dms]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dms]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DMS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DMS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dms]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DMS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DMS FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Otx2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dms OCA], [http://pdbe.org/2dms PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dms RCSB], [http://www.ebi.ac.uk/pdbsum/2dms PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dms ProSAT], [http://www.topsan.org/Proteins/RSGI/2dms TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dms OCA], [https://pdbe.org/2dms PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dms RCSB], [https://www.ebi.ac.uk/pdbsum/2dms PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dms ProSAT], [https://www.topsan.org/Proteins/RSGI/2dms TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/OTX2_MOUSE OTX2_MOUSE]] Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.
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[https://www.uniprot.org/uniprot/OTX2_MOUSE OTX2_MOUSE] Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Inoue, M]]
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[[Category: Mus musculus]]
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[[Category: Kigawa, T]]
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[[Category: Inoue M]]
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[[Category: Koshiba, S]]
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[[Category: Kigawa T]]
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[[Category: Ohnishi, S]]
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[[Category: Koshiba S]]
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[[Category: Structural genomic]]
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[[Category: Ohnishi S]]
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[[Category: Saito, K]]
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[[Category: Saito K]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: Dna binding protein]]
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[[Category: Homeobox domain]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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[[Category: Three helices with the dna binding helix-turn-helix motif]]
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Current revision

Solution structure of the homeobox domain of Homeobox protein OTX2

PDB ID 2dms

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