2dnv
From Proteopedia
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==Solution Structure of RSGI RUH-055, a Chromo Domain from Mus musculus cDNA== | ==Solution Structure of RSGI RUH-055, a Chromo Domain from Mus musculus cDNA== | ||
- | <StructureSection load='2dnv' size='340' side='right'caption='[[2dnv | + | <StructureSection load='2dnv' size='340' side='right'caption='[[2dnv]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2dnv]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2dnv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DNV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DNV FirstGlance]. <br> |
- | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dnv OCA], [https://pdbe.org/2dnv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dnv RCSB], [https://www.ebi.ac.uk/pdbsum/2dnv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dnv ProSAT], [https://www.topsan.org/Proteins/RSGI/2dnv TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/CBX8_MOUSE CBX8_MOUSE] Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: | + | [[Category: Mus musculus]] |
- | [[Category: Hirota | + | [[Category: Hirota H]] |
- | [[Category: Kigawa | + | [[Category: Kigawa T]] |
- | [[Category: | + | [[Category: Ruhul Momen AZM]] |
- | + | [[Category: Tomizawa T]] | |
- | [[Category: Tomizawa | + | [[Category: Yokoyama S]] |
- | [[Category: Yokoyama | + | |
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Current revision
Solution Structure of RSGI RUH-055, a Chromo Domain from Mus musculus cDNA
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