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2dnx
From Proteopedia
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| - | [[Image:2dnx.jpg|left|200px]]<br /><applet load="2dnx" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2dnx" /> | ||
| - | '''Solution structure of RSGI RUH-063, an N-terminal domain of Syntaxin 12 from human cDNA'''<br /> | ||
| - | == | + | ==Solution structure of RSGI RUH-063, an N-terminal domain of Syntaxin 12 from human cDNA== |
| - | + | <StructureSection load='2dnx' size='340' side='right'caption='[[2dnx]]' scene=''> | |
| - | [ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[2dnx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DNX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DNX FirstGlance]. <br> |
| - | [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dnx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dnx OCA], [https://pdbe.org/2dnx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dnx RCSB], [https://www.ebi.ac.uk/pdbsum/2dnx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dnx ProSAT], [https://www.topsan.org/Proteins/RSGI/2dnx TOPSAN]</span></td></tr> |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/STX12_HUMAN STX12_HUMAN] SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity). | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | + | Check<jmol> | |
| - | [ | + | <jmolCheckbox> |
| - | [[ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dn/2dnx_consurf.spt"</scriptWhenChecked> |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | + | </jmolCheckbox> | |
| - | [ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dnx ConSurf]. |
| - | [[ | + | <div style="clear:both"></div> |
| - | [ | + | |
| - | + | ||
| - | + | ==See Also== | |
| + | *[[Syntaxin 3D structures|Syntaxin 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Abe T]] | ||
| + | [[Category: Hirota H]] | ||
| + | [[Category: Muto Y]] | ||
| + | [[Category: Yokoyama S]] | ||
Current revision
Solution structure of RSGI RUH-063, an N-terminal domain of Syntaxin 12 from human cDNA
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Categories: Homo sapiens | Large Structures | Abe T | Hirota H | Muto Y | Yokoyama S
