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2eqn
From Proteopedia
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==Solution structure of the NAF1 domain of Hypothetical protein BC008207 [Homo sapiens]== | ==Solution structure of the NAF1 domain of Hypothetical protein BC008207 [Homo sapiens]== | ||
| - | <StructureSection load='2eqn' size='340' side='right' caption='[[2eqn | + | <StructureSection load='2eqn' size='340' side='right'caption='[[2eqn]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2eqn]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2eqn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EQN FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eqn OCA], [https://pdbe.org/2eqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eqn RCSB], [https://www.ebi.ac.uk/pdbsum/2eqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eqn ProSAT], [https://www.topsan.org/Proteins/RSGI/2eqn TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/NAF1_HUMAN NAF1_HUMAN] RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4.<ref>PMID:16618814</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eq/2eqn_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eq/2eqn_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Dang | + | [[Category: Large Structures]] |
| - | [[Category: Inoue | + | [[Category: Dang W]] |
| - | [[Category: Kigawa | + | [[Category: Inoue M]] |
| - | [[Category: Muto | + | [[Category: Kigawa T]] |
| - | + | [[Category: Muto Y]] | |
| - | [[Category: Shirouzu | + | [[Category: Shirouzu M]] |
| - | [[Category: Terada | + | [[Category: Terada T]] |
| - | [[Category: Yokoyama | + | [[Category: Yokoyama S]] |
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Current revision
Solution structure of the NAF1 domain of Hypothetical protein BC008207 [Homo sapiens]
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Categories: Homo sapiens | Large Structures | Dang W | Inoue M | Kigawa T | Muto Y | Shirouzu M | Terada T | Yokoyama S
