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2frz

From Proteopedia

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[[Image:2frz.jpg|left|200px]]<br /><applet load="2frz" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2frz, resolution 2.1&Aring;" />
 
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'''Crystal Structure of Cytochrome P450cam mutant (F87W/Y96F/V247L/C334A)'''<br />
 
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==About this Structure==
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==Crystal Structure of Cytochrome P450cam mutant (F87W/Y96F/V247L/C334A)==
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2FRZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida] with <scene name='pdbligand=K:'>K</scene> and <scene name='pdbligand=HEM:'>HEM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Camphor_5-monooxygenase Camphor 5-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.15.1 1.14.15.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FRZ OCA].
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<StructureSection load='2frz' size='340' side='right'caption='[[2frz]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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[[Category: Camphor 5-monooxygenase]]
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== Structural highlights ==
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[[Category: Pseudomonas putida]]
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<table><tr><td colspan='2'>[[2frz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FRZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FRZ FirstGlance]. <br>
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[[Category: Single protein]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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[[Category: Bell, S G.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
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[[Category: Rao, Z.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2frz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2frz OCA], [https://pdbe.org/2frz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2frz RCSB], [https://www.ebi.ac.uk/pdbsum/2frz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2frz ProSAT]</span></td></tr>
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[[Category: Wong, L L.]]
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</table>
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[[Category: Xu, F.]]
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== Function ==
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[[Category: HEM]]
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[https://www.uniprot.org/uniprot/CPXA_PSEPU CPXA_PSEPU] Involved in a camphor oxidation system.
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[[Category: K]]
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== Evolutionary Conservation ==
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[[Category: cytochrome p450]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: mutant]]
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Check<jmol>
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[[Category: p450cam]]
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fr/2frz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2frz ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:24:29 2008''
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==See Also==
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*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Pseudomonas putida]]
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[[Category: Bell SG]]
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[[Category: Rao Z]]
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[[Category: Wong LL]]
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[[Category: Xu F]]

Current revision

Crystal Structure of Cytochrome P450cam mutant (F87W/Y96F/V247L/C334A)

PDB ID 2frz

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