2k5t

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (19:10, 29 May 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2k5t.png|left|200px]]
 
-
<!--
+
==Solution NMR Structure of Putative N-Acetyl Transferase YhhK from E. coli Bound to Coenzyme A: Northeast Structural Genomics Consortium Target ET106==
-
The line below this paragraph, containing "STRUCTURE_2k5t", creates the "Structure Box" on the page.
+
<StructureSection load='2k5t' size='340' side='right'caption='[[2k5t]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2k5t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K5T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K5T FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>
-
{{STRUCTURE_2k5t| PDB=2k5t | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k5t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k5t OCA], [https://pdbe.org/2k5t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k5t RCSB], [https://www.ebi.ac.uk/pdbsum/2k5t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k5t ProSAT], [https://www.topsan.org/Proteins/NESGC/2k5t TOPSAN]</span></td></tr>
-
 
+
</table>
-
===Solution NMR Structure of Putative N-Acetyl Transferase YhhK from E. coli Bound to Coenzyme A: Northeast Structural Genomics Consortium Target ET106===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/PANZ_ECOLI PANZ_ECOLI] Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion. Binding of CoA or a derivative to PanZ leads to interaction with PanD, which promotes the processing and activation of pro-PanD, and subsequent substrate-mediated inhibition of the active form of PanD (PubMed:23170229, PubMed:25910242). Inhibition of PanD activity is probably the primary metabolic role of PanZ, allowing negative feedback regulation of pantothenate biosynthesis by CoA (PubMed:25910242).<ref>PMID:23170229</ref> <ref>PMID:25910242</ref>
-
 
+
== Evolutionary Conservation ==
-
==About this Structure==
+
[[Image:Consurf_key_small.gif|200px|right]]
-
2K5T is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k12 Escherichia coli k12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K5T OCA].
+
Check<jmol>
-
[[Category: Escherichia coli k12]]
+
<jmolCheckbox>
-
[[Category: Single protein]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k5/2k5t_consurf.spt"</scriptWhenChecked>
-
[[Category: Arrowsmith, C H.]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Cort, J R.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Kennedy, M A.]]
+
</jmolCheckbox>
-
[[Category: Montelione, G T.]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k5t ConSurf].
-
[[Category: NESG, Northeast Structural Genomics Consortium.]]
+
<div style="clear:both"></div>
-
[[Category: Yee, A.]]
+
== References ==
-
[[Category: Bound ligand]]
+
<references/>
-
[[Category: Coa]]
+
__TOC__
-
[[Category: Coenzyme some]]
+
</StructureSection>
-
[[Category: N-acetyl transferase]]
+
[[Category: Escherichia coli K-12]]
-
[[Category: Nesg]]
+
[[Category: Large Structures]]
-
[[Category: Northeast structural genomics consortium]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Protein structure initiative]]
+
[[Category: Cort JR]]
-
[[Category: Psi-2]]
+
[[Category: Kennedy MA]]
-
[[Category: Structural genomic]]
+
[[Category: Montelione GT]]
-
[[Category: Unknown function]]
+
[[Category: Yee A]]
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 29 01:57:21 2008''
+

Current revision

Solution NMR Structure of Putative N-Acetyl Transferase YhhK from E. coli Bound to Coenzyme A: Northeast Structural Genomics Consortium Target ET106

PDB ID 2k5t

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2k5t"
Personal tools