This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2rq9
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
==Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new== | ==Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new== | ||
| - | <StructureSection load='2rq9' size='340' side='right' caption='[[2rq9 | + | <StructureSection load='2rq9' size='340' side='right'caption='[[2rq9]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2rq9]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2rq9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RQ9 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rq9 OCA], [https://pdbe.org/2rq9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rq9 RCSB], [https://www.ebi.ac.uk/pdbsum/2rq9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rq9 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/FGF1_HUMAN FGF1_HUMAN] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:8663044</ref> <ref>PMID:16597617</ref> <ref>PMID:20145243</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 20: | Line 21: | ||
==See Also== | ==See Also== | ||
| - | *[[Fibroblast growth factor|Fibroblast growth factor]] | + | *[[Fibroblast growth factor 3D structures|Fibroblast growth factor 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Enomoto | + | [[Category: Large Structures]] |
| - | [[Category: Hosoda | + | [[Category: Enomoto M]] |
| - | [[Category: Inoue | + | [[Category: Hosoda K]] |
| - | [[Category: Ishii | + | [[Category: Inoue Y]] |
| - | [[Category: Nameki | + | [[Category: Ishii T]] |
| - | [[Category: Tochio | + | [[Category: Nameki N]] |
| - | [[Category: Wakamatsu | + | [[Category: Tochio N]] |
| - | [[Category: Xiang | + | [[Category: Wakamatsu K]] |
| - | + | [[Category: Xiang L]] | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Solution structure of human acidic fibroblast growth factor (aFGF) in the presence of a protein stabilizer NDSB-new
| |||||||||||
Categories: Homo sapiens | Large Structures | Enomoto M | Hosoda K | Inoue Y | Ishii T | Nameki N | Tochio N | Wakamatsu K | Xiang L
