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2yse
From Proteopedia
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| - | [[Image:2yse.jpg|left|200px]]<br /><applet load="2yse" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2yse" /> | ||
| - | '''Solution structure of the second WW domain from the human membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1. MAGI-1'''<br /> | ||
| - | == | + | ==Solution structure of the second WW domain from the human membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1. MAGI-1== |
| - | + | <StructureSection load='2yse' size='340' side='right'caption='[[2yse]]' scene=''> | |
| - | [ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[2yse]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YSE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YSE FirstGlance]. <br> |
| - | [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yse FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yse OCA], [https://pdbe.org/2yse PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yse RCSB], [https://www.ebi.ac.uk/pdbsum/2yse PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yse ProSAT], [https://www.topsan.org/Proteins/RSGI/2yse TOPSAN]</span></td></tr> | |
| - | [ | + | </table> |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/MAGI1_HUMAN MAGI1_HUMAN] May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity). | |
| - | [ | + | == Evolutionary Conservation == |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | [ | + | Check<jmol> |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ys/2yse_consurf.spt"</scriptWhenChecked> | |
| - | [[ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | + | </jmolCheckbox> | |
| - | [ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yse ConSurf]. |
| - | [[ | + | <div style="clear:both"></div> |
| - | + | ||
| - | + | ||
| - | + | ==See Also== | |
| + | *[[Guanylate kinase 3D structures|Guanylate kinase 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Harada T]] | ||
| + | [[Category: Kigawa T]] | ||
| + | [[Category: Koshiba S]] | ||
| + | [[Category: Ohnishi S]] | ||
| + | [[Category: Sato M]] | ||
| + | [[Category: Watanabe S]] | ||
| + | [[Category: Yokoyama S]] | ||
Current revision
Solution structure of the second WW domain from the human membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1. MAGI-1
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Categories: Homo sapiens | Large Structures | Harada T | Kigawa T | Koshiba S | Ohnishi S | Sato M | Watanabe S | Yokoyama S
