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2yt9

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==Solution structure of C2H2 type Zinc finger domain 345 in Zinc finger protein 278==
==Solution structure of C2H2 type Zinc finger domain 345 in Zinc finger protein 278==
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<StructureSection load='2yt9' size='340' side='right' caption='[[2yt9]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2yt9' size='340' side='right'caption='[[2yt9]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2yt9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YT9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YT9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2yt9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YT9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YT9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PATZ, RIAZ, ZBTB19, ZNF278, ZSG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yt9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yt9 OCA], [http://pdbe.org/2yt9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yt9 RCSB], [http://www.ebi.ac.uk/pdbsum/2yt9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yt9 ProSAT], [http://www.topsan.org/Proteins/RSGI/2yt9 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yt9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yt9 OCA], [https://pdbe.org/2yt9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yt9 RCSB], [https://www.ebi.ac.uk/pdbsum/2yt9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yt9 ProSAT], [https://www.topsan.org/Proteins/RSGI/2yt9 TOPSAN]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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[[http://www.uniprot.org/uniprot/PATZ1_HUMAN PATZ1_HUMAN]] Note=A chromosomal aberration involving PATZ1 is associated with small round cell sarcoma. Translocation t(1;22)(p36.1;q12) with EWSR1.
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[https://www.uniprot.org/uniprot/PATZ1_HUMAN PATZ1_HUMAN] Note=A chromosomal aberration involving PATZ1 is associated with small round cell sarcoma. Translocation t(1;22)(p36.1;q12) with EWSR1.
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PATZ1_HUMAN PATZ1_HUMAN]] Transcriptional repressor.<ref>PMID:10713105</ref>
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[https://www.uniprot.org/uniprot/PATZ1_HUMAN PATZ1_HUMAN] Transcriptional repressor.<ref>PMID:10713105</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yt/2yt9_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yt/2yt9_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Inoue, M]]
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[[Category: Large Structures]]
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[[Category: Kasahara, N]]
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[[Category: Inoue M]]
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[[Category: Kigawa, T]]
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[[Category: Kasahara N]]
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[[Category: Muto, Y]]
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[[Category: Kigawa T]]
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[[Category: Structural genomic]]
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[[Category: Muto Y]]
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[[Category: Shirouzu, M]]
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[[Category: Shirouzu M]]
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[[Category: Terada, T]]
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[[Category: Terada T]]
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[[Category: Tsuda, K]]
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[[Category: Tsuda K]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: C2h2]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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[[Category: Transcription]]
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[[Category: Zinc-finger]]
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Current revision

Solution structure of C2H2 type Zinc finger domain 345 in Zinc finger protein 278

PDB ID 2yt9

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