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3v2b

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==Human poly(adp-ribose) polymerase 15 (ARTD7, BAL3), macro domain 2 in complex with adenosine-5-diphosphoribose==
==Human poly(adp-ribose) polymerase 15 (ARTD7, BAL3), macro domain 2 in complex with adenosine-5-diphosphoribose==
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<StructureSection load='3v2b' size='340' side='right' caption='[[3v2b]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='3v2b' size='340' side='right'caption='[[3v2b]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3v2b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3kh6 3kh6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V2B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3v2b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3kh6 3kh6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V2B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V2B FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AR6:[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL+[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL]+HYDROGEN+PHOSPHATE'>AR6</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAL3, PARP15 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AR6:[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL+[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL]+HYDROGEN+PHOSPHATE'>AR6</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v2b OCA], [https://pdbe.org/3v2b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v2b RCSB], [https://www.ebi.ac.uk/pdbsum/3v2b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v2b ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v2b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3v2b RCSB], [http://www.ebi.ac.uk/pdbsum/3v2b PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PAR15_HUMAN PAR15_HUMAN]] Transcriptional repressor. Has ADP-ribosyltransferase activity.
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[https://www.uniprot.org/uniprot/PAR15_HUMAN PAR15_HUMAN] Transcriptional repressor. Has ADP-ribosyltransferase activity.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3v2b" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Poly (ADP-ribose) polymerase|Poly (ADP-ribose) polymerase]]
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*[[Poly(ADP-ribose) polymerase 3D structures|Poly(ADP-ribose) polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H]]
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[[Category: Large Structures]]
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[[Category: Berglund, H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C]]
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[[Category: Berglund H]]
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[[Category: Collins, R]]
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[[Category: Bountra C]]
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[[Category: Edwards, A M]]
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[[Category: Collins R]]
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[[Category: Flodin, S]]
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[[Category: Edwards AM]]
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[[Category: Flores, A]]
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[[Category: Flodin S]]
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[[Category: Graslund, S]]
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[[Category: Flores A]]
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[[Category: Hammarstrom, M]]
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[[Category: Graslund S]]
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[[Category: Johansson, I]]
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[[Category: Hammarstrom M]]
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[[Category: Kallas, A]]
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[[Category: Johansson I]]
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[[Category: Karlberg, T]]
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[[Category: Kallas A]]
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[[Category: Kotenyova, T]]
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[[Category: Karlberg T]]
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[[Category: Kotzcsh, A]]
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[[Category: Kotenyova T]]
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[[Category: Kraulis, P]]
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[[Category: Kotzcsh A]]
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[[Category: Moche, M]]
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[[Category: Kraulis P]]
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[[Category: Nielsen, T K]]
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[[Category: Moche M]]
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[[Category: Nordlund, P]]
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[[Category: Nielsen TK]]
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[[Category: Nyman, T]]
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[[Category: Nordlund P]]
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[[Category: Persson, C]]
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[[Category: Nyman T]]
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[[Category: Roos, A K]]
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[[Category: Persson C]]
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[[Category: Structural genomic]]
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[[Category: Roos AK]]
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[[Category: Schuler, H]]
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[[Category: Schuler H]]
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[[Category: Schutz, P]]
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[[Category: Schutz P]]
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[[Category: Siponen, M I]]
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[[Category: Siponen MI]]
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[[Category: Thorsell, A G]]
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[[Category: Thorsell AG]]
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[[Category: Tresaugues, L]]
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[[Category: Tresaugues L]]
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[[Category: Weigelt, J]]
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[[Category: Van den berg S]]
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[[Category: Welin, M]]
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[[Category: Weigelt J]]
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[[Category: Wisniewska, M]]
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[[Category: Welin M]]
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[[Category: Berg, S Van den]]
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[[Category: Wisniewska M]]
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[[Category: Adp-ribose]]
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[[Category: Adp-ribosylation]]
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[[Category: B-aggressive lymphoma protein 3]]
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[[Category: Bal3]]
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[[Category: Glycosyltransferase]]
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[[Category: Nucleus]]
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[[Category: Sgc]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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[[Category: Transferase]]
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Current revision

Human poly(adp-ribose) polymerase 15 (ARTD7, BAL3), macro domain 2 in complex with adenosine-5-diphosphoribose

PDB ID 3v2b

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