This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Beta-lactamase 3D structures

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:10, 30 May 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 248: Line 248:
**[[5wih]] - EcBlac B Ndm-12<br />
**[[5wih]] - EcBlac B Ndm-12<br />
**[[6bm9]] – EcBlac B Vim-2<br />
**[[6bm9]] – EcBlac B Vim-2<br />
-
**[[6lvj]] - EcBlac Imp-6 <br />
+
**[[7xhx]] - EcBlac Imp-6 <br />
**[[6skp]], [[6skq]], [[6skr]] - EcBlac Oxa-10 <br />
**[[6skp]], [[6skq]], [[6skr]] - EcBlac Oxa-10 <br />
**[[6ovz]] - EcBlac <br />
**[[6ovz]] - EcBlac <br />
Line 418: Line 418:
*'''AmpC β-lactamase'''
*'''AmpC β-lactamase'''
-
**[[1ke4]], [[2bls]], [[2zj9]], [[3bls]], [[5gzw]], [[6t3d]] – EcBlac<br />
+
**[[1ke4]], [[2bls]], [[2zj9]], [[3bls]], [[5gzw]], [[6t3d]], [[7cin]] – EcBlac<br />
**[[1l0d]], [[1l0e]], [[1l0f]], [[1l0g]], [[4kg6]], [[5joc]] - EcBlac (mutant)
**[[1l0d]], [[1l0e]], [[1l0f]], [[1l0g]], [[4kg6]], [[5joc]] - EcBlac (mutant)
**[[6lc7]] - EncBlac <br />
**[[6lc7]] - EncBlac <br />
Line 426: Line 426:
**[[5e2g]] – Blac – ''Burkholderia cenocepacia''<br />
**[[5e2g]] – Blac – ''Burkholderia cenocepacia''<br />
-
*AmpC -lactamase binary complex
+
*AmpC beta-lactamase binary complex
**[[1fcn]] – EcBlac (mutant) + substrate<br />
**[[1fcn]] – EcBlac (mutant) + substrate<br />
Line 447: Line 447:
**[[3fai]], [[1x8h]], [[3sw3]], [[3t9m]] - AhBlac B (mutant)<br />
**[[3fai]], [[1x8h]], [[3sw3]], [[3t9m]] - AhBlac B (mutant)<br />
**[[6p96]] - KpBlac Oxa-48 <br />
**[[6p96]] - KpBlac Oxa-48 <br />
 +
**[[7o5t]], [[7o9n]], [[7peh]] - KpBlac D<br />
 +
**[[7pgo]] - KpBlac D (mutant)<br />
**[[3rxw]], [[3rxx]], [[2ov5]], [[5ul8]] – KpBlac Kpc-2
**[[3rxw]], [[3rxx]], [[2ov5]], [[5ul8]] – KpBlac Kpc-2
-
**[[6xd5]] - KpBlac Kpc-2 (mutant)<br />
+
**[[6xd5]], [[7ljk]], [[7lk8]], [[7tb7]], [[7tbx]] - KpBlac Kpc-2 (mutant)<br />
**[[6qwd]] - KpBlac Kpc-3<br />
**[[6qwd]] - KpBlac Kpc-3<br />
**[[6qwe]] - KpBlac Kpc-4<br />
**[[6qwe]] - KpBlac Kpc-4<br />
Line 465: Line 467:
**[[6p97]], [[6p98]], [[6p99]], [[6p9c]], [[6pk0]] - KpBlac Oxa-48 + antibiotic<br />
**[[6p97]], [[6p98]], [[6p99]], [[6p9c]], [[6pk0]] - KpBlac Oxa-48 + antibiotic<br />
 +
**[[67dml]] - KpBlac Oxa-48 + inhibitor<br />
**[[3rxw]], [[3rxx]], [[2ov5]], [[5ul8]] – KpBlac Kpc<br />
**[[3rxw]], [[3rxx]], [[2ov5]], [[5ul8]] – KpBlac Kpc<br />
**[[5eec]], [[6td1]] - KpBlac Kpc-2 + boronic acid inhibitor<br />
**[[5eec]], [[6td1]] - KpBlac Kpc-2 + boronic acid inhibitor<br />
-
**[[4zbe]], [[6b1y]], [[6b1x]], [[6b1w]], [[6b1j]], [[6b1h]], [[6b1f]], [[6d15]], [[6d16]], [[6d17]], [[6d18]], [[6d19]], [[6j8q]], [[6jn3]], [[6jn4]], [[6jn5]], [[6m7i]], [[6mey]], [[6mll]], [[6mnp]], [[6qw9]], [[6td0]], [[6v1j]] - KpBlac Kpc-2 + inhibitor<br />
+
**[[4zbe]], [[6b1y]], [[6b1x]], [[6b1w]], [[6b1j]], [[6b1h]], [[6b1f]], [[6d15]], [[6d16]], [[6d17]], [[6d18]], [[6d19]], [[6j8q]], [[6jn3]], [[6jn4]], [[6jn5]], [[6m7i]], [[6mey]], [[6mll]], [[6mnp]], [[6qw9]], [[6td0]], [[6v1j]], [[7vqn]], [[7ti2]] - KpBlac Kpc-2 + inhibitor<br />
-
**[[5uj3]], [[5uj4]], [[6v7i]], [[7a61]] - KpBlac Kpc-2 + antibiotic<br />
+
**[[5uj3]], [[5uj4]], [[6v7i]], [[7a61]], [[7pep]], [[7tc1]] - KpBlac Kpc-2 + antibiotic<br />
-
**[[6xd7]], [[6z23]], [[6z25]] - KpBlac Kpc-2 (mutant) + antibiotic<br />
+
**[[6xd7]], [[6z23]], [[6z25]], [[7llb]], [[7llh]], [[7lnl]], [[7lr9]], [[7pse]], [[7psf]] - KpBlac Kpc-2 (mutant) + antibiotic<br />
**[[6qwa]] - KpBlac Kpc-3 + inhibitor<br />
**[[6qwa]] - KpBlac Kpc-3 + inhibitor<br />
**[[6qwb]], [[6qwc]] - KpBlac Kpc-4 + inhibitor<br />
**[[6qwb]], [[6qwc]] - KpBlac Kpc-4 + inhibitor<br />
Line 492: Line 495:
**[[1fr1]], [[1fr6]] – CfBlac <br />
**[[1fr1]], [[1fr6]] – CfBlac <br />
**[[1i2s]], [[4blm]] – BlBlac<br />
**[[1i2s]], [[4blm]] – BlBlac<br />
-
**[[2gdn]], [[3zhh]], [[5oyo]], [[5nj2]] – MtBlac – ''Mycobacterium tuberculosis''<br />
+
**[[2gdn]], [[3zhh]], [[5oyo]], [[5nj2]], [[7k8l]] – MtBlac – ''Mycobacterium tuberculosis''<br />
**[[4whi]] – MtBlac C terminal<br />
**[[4whi]] – MtBlac C terminal<br />
-
**[[4jlf]], [[6h28]], [[6h27]] - MtBlac (mutant)<br />
+
**[[4jlf]], [[6h28]], [[6h27]], [[7a5u]], [[7a5w]] - MtBlac (mutant)<br />
**[[2jc7]], [[3g4p]] – AbBlac <br />
**[[2jc7]], [[3g4p]] – AbBlac <br />
**[[3byd]] – KoBlac <br />
**[[3byd]] – KoBlac <br />
Line 516: Line 519:
**[[5oe2]] – KpBlac Oxa-245 <br />
**[[5oe2]] – KpBlac Oxa-245 <br />
**[[6gth]] – KpBlac <br />
**[[6gth]] – KpBlac <br />
 +
**[[7oda]] – Blac Oxa-436 – ''Enterobacter asburiae'' <br />
**[[3wrt]] – ChBlac – ''Chromohalobacter''<br />
**[[3wrt]] – ChBlac – ''Chromohalobacter''<br />
**[[3wrz]], [[3ws0]], [[3ws1]], [[3ws2]], [[3ws3]], [[3ws4]], [[3ws5]] – ChBlac (mutant)<br />
**[[3wrz]], [[3ws0]], [[3ws1]], [[3ws2]], [[3ws3]], [[3ws4]], [[3ws5]] – ChBlac (mutant)<br />
Line 523: Line 527:
**[[6mu9]] – Blac – ''Bacillus megaterium''<br />
**[[6mu9]] – Blac – ''Bacillus megaterium''<br />
**[[6ch0]], [[6cgy]] – AaBlac – ''Alicyclobacillus acidoterrestris''<br />
**[[6ch0]], [[6cgy]] – AaBlac – ''Alicyclobacillus acidoterrestris''<br />
-
**[[6edm]] – CdBlac <br />
+
**[[6edm]], [[7lno]], [[7lnr]], [[7me9]] – CdBlac <br />
**[[6izc]] – VpBlac – ''Vibrio parahaemolyticus''<br />
**[[6izc]] – VpBlac – ''Vibrio parahaemolyticus''<br />
**[[6izd]] – VpBlac (mutant)<br />
**[[6izd]] – VpBlac (mutant)<br />
Line 539: Line 543:
**[[1ga0]] - EncBlac + inhibitor<br />
**[[1ga0]] - EncBlac + inhibitor<br />
**[[1i2w]] – BlBlac + cifoxitin<br />
**[[1i2w]] – BlBlac + cifoxitin<br />
-
**[[3cg5]], [[4q8i]], [[4qb8]] – MtBlac + antibiotic<br />
+
**[[3cg5]], [[4q8i]], [[4qb8]], [[7k8e]], [[7k8f]], [[7k8h]], [[7k8k]] – MtBlac + antibiotic<br />
**[[3n8s]], [[3ny4]], [[3n6i]], [[3n7w]], [[3n8l]], [[3n8r]], [[3nbl]], [[3nc8]], [[3nck]], [[3nde]], [[3ndg]] - MtBlac (mutant) + antibiotic<br />
**[[3n8s]], [[3ny4]], [[3n6i]], [[3n7w]], [[3n8l]], [[3n8r]], [[3nbl]], [[3nc8]], [[3nck]], [[3nde]], [[3ndg]] - MtBlac (mutant) + antibiotic<br />
**[[3dwz]], [[3iqa]], [[3m6b]], [[3m6h]], [[4df6]], [[6h2k]], [[6h2i]], [[6h2h]], [[6h2g]], [[6h2c]] – MtBlac + inhibitor<br />
**[[3dwz]], [[3iqa]], [[3m6b]], [[3m6h]], [[4df6]], [[6h2k]], [[6h2i]], [[6h2h]], [[6h2g]], [[6h2c]] – MtBlac + inhibitor<br />
Line 550: Line 554:
**[[6uqs]], [[6uqt]], [[6uqu]], [[6ur3]] – PaBlac (mutant) + boronic acid inhibitor<br />
**[[6uqs]], [[6uqt]], [[6uqu]], [[6ur3]] – PaBlac (mutant) + boronic acid inhibitor<br />
**[[6cgz]] – AaBlac + lactone derivative<br />
**[[6cgz]] – AaBlac + lactone derivative<br />
 +
**[[7kep]], [[7keq]], [[7ker]], [[7lnq]], [[7mea]], [[7meb]], [[7mec]], [[7med]], [[7mee]], [[7mef]], [[7meg]], [[7meh]] – CdBlac + drug<br />
**[[6pqc]] – CdBlac (mutant) + antibiotic <br />
**[[6pqc]] – CdBlac (mutant) + antibiotic <br />
**[[7doo]] – BmBlac + antibiotic <br />
**[[7doo]] – BmBlac + antibiotic <br />
 +
**[[7ddm]] – BmBlac + peptide <br />
 +
 +
*Serine beta-lactamase (ClbP)
 +
 +
**[[7mde]], [[7mdf]] – EcClbP (mutant)<br />
 +
**[[7ul6]] – EcClbP – Cryo EM <br />
 +
**[[3o3v]] – EcClbP peptidase domain 38-372<br />
 +
**[[4e6w]], [[4e6x]], [[7mdc]] – EcClbP + boronic acid inhibitor<br />
 +
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D Structures of Beta-lactamase

Updated on 30-May-2024

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

Personal tools