7zyh
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human CPSF30 in complex with hFip1== | |
| - | + | <StructureSection load='7zyh' size='340' side='right'caption='[[7zyh]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7zyh]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZYH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zyh OCA], [https://pdbe.org/7zyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zyh RCSB], [https://www.ebi.ac.uk/pdbsum/7zyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zyh ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Migenda Herranz | + | == Function == |
| - | [[Category: Muckenfuss | + | [https://www.uniprot.org/uniprot/CPSF4_HUMAN CPSF4_HUMAN] Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).<ref>PMID:9224719</ref> <ref>PMID:14749727</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Clerici M]] | ||
| + | [[Category: Jinek M]] | ||
| + | [[Category: Migenda Herranz AC]] | ||
| + | [[Category: Muckenfuss LM]] | ||
Current revision
Crystal structure of human CPSF30 in complex with hFip1
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