Glutathione S-transferase
From Proteopedia
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*'''epsilon glutathione S-transferase''' has a role in insecticide resistance<ref>PMID:26487708</ref>. | *'''epsilon glutathione S-transferase''' has a role in insecticide resistance<ref>PMID:26487708</ref>. | ||
*'''kappa glutathione S-transferase''' is found in mitochondria and peroxisomes. It may be involved in lipid metabolism<ref>PMID:21428694</ref>. | *'''kappa glutathione S-transferase''' is found in mitochondria and peroxisomes. It may be involved in lipid metabolism<ref>PMID:21428694</ref>. | ||
| + | *'''mu glutathione S-transferase''' detoxify carcinogens in tobacco smoke<ref>PMID:8485718</ref>. | ||
==Relevance== | ==Relevance== | ||
Revision as of 07:20, 26 June 2024
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References
- ↑ Oakley A. Glutathione transferases: a structural perspective. Drug Metab Rev. 2011 May;43(2):138-51. doi: 10.3109/03602532.2011.558093. Epub, 2011 Mar 23. PMID:21428697 doi:http://dx.doi.org/10.3109/03602532.2011.558093
- ↑ Wongsantichon J, Robinson RC, Ketterman AJ. Epsilon glutathione transferases possess a unique class-conserved subunit interface motif that directly interacts with glutathione in the active site. Biosci Rep. 2015 Oct 20;35(6). pii: e00272. doi: 10.1042/BSR20150183. PMID:26487708 doi:http://dx.doi.org/10.1042/BSR20150183
- ↑ Morel F, Aninat C. The glutathione transferase kappa family. Drug Metab Rev. 2011 May;43(2):281-91. PMID:21428694 doi:10.3109/03602532.2011.556122
- ↑ Nazar-Stewart V, Motulsky AG, Eaton DL, White E, Hornung SK, Leng ZT, Stapleton P, Weiss NS. The glutathione S-transferase mu polymorphism as a marker for susceptibility to lung carcinoma. Cancer Res. 1993 May 15;53(10 Suppl):2313-8 PMID:8485718
- ↑ Rossjohn J, Feil SC, Wilce MC, Sexton JL, Spithill TW, Parker MW. Crystallization, structural determination and analysis of a novel parasite vaccine candidate: Fasciola hepatica glutathione S-transferase. J Mol Biol. 1997 Nov 7;273(4):857-72. PMID:9367777 doi:10.1006/jmbi.1997.1338
