Netrin receptor

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Line 45: Line 45:
**[[4v2a]] – hUNC5A ectodomain <BR />
**[[4v2a]] – hUNC5A ectodomain <BR />
-
*Netrin receptor UNC5B
+
*Netrin receptor UNC5B or UNC5B
**[[6ool]] – mUNC5B ectodomain<BR />
**[[6ool]] – mUNC5B ectodomain<BR />
 +
**[[1wmg]] – mUNC5B death domain <BR />
**[[3g5b]] – rUNC5B cytoplasmic domain 541-945 (mutant)<BR />
**[[3g5b]] – rUNC5B cytoplasmic domain 541-945 (mutant)<BR />
Line 57: Line 58:
**[[5ftt]], [[5ftu]] – mUNC5D Ig1, Ig2, TSP1 domains + FLRT2 LRR domain + latrophilin 3<BR />
**[[5ftt]], [[5ftu]] – mUNC5D Ig1, Ig2, TSP1 domains + FLRT2 LRR domain + latrophilin 3<BR />
-
*Netrin receptor UNC5H2
 
- 
-
**[[1wmg]] – mUNC5H2 death domain <BR />
 
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:23, 16 July 2024

Glycosylated human netrin receptor DCC fibronectin type V-VI domains (green) complex with neutrin-1 (grey), sulfate, Ca+2 and Cl-1 ions (PDB code 4urt)

Drag the structure with the mouse to rotate

3D Structures of netrin receptor

Updated on 16-July-2024

References

  1. ↑ Moore SW, Tessier-Lavigne M, Kennedy TE. Netrins and their receptors. Adv Exp Med Biol. 2007;621:17-31. doi: 10.1007/978-0-387-76715-4_2. PMID:18269208 doi:http://dx.doi.org/10.1007/978-0-387-76715-4_2
  2. ↑ Keleman K, Dickson BJ. Short Neuron. 2001 Nov 20;32(4):605-17. PMID:11719202 doi:10.1016/s0896-6273(01)00505-0
  3. ↑ Lu X, Le Noble F, Yuan L, Jiang Q, De Lafarge B, Sugiyama D, Bréant C, Claes F, De Smet F, Thomas JL, Autiero M, Carmeliet P, Tessier-Lavigne M, Eichmann A. The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system. Nature. 2004 Nov 11;432(7014):179-86. PMID:15510105 doi:10.1038/nature03080
  4. ↑ Takemoto M, Hattori Y, Zhao H, Sato H, Tamada A, Sasaki S, Nakajima K, Yamamoto N. Laminar and areal expression of unc5d and its role in cortical cell survival. Cereb Cortex. 2011 Aug;21(8):1925-34. PMID:21216843 doi:10.1093/cercor/bhq265
  5. ↑ Mehlen P, Llambi F. Role of netrin-1 and netrin-1 dependence receptors in colorectal cancers. Br J Cancer. 2005 Jul 11;93(1):1-6. PMID:15956977 doi:http://dx.doi.org/10.1038/sj.bjc.6602656

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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