8i0i

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'''Unreleased structure'''
 
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The entry 8i0i is ON HOLD
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==dmCTPS with dATP dUTP dGTP and DON==
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<StructureSection load='8i0i' size='340' side='right'caption='[[8i0i]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
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Authors: Guo, C.J., Liu, J.L.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8i0i]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8I0I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8I0I FirstGlance]. <br>
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Description: dmCTPS with dATP dUTP dGTP and DON
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTP:2-DEOXYADENOSINE+5-TRIPHOSPHATE'>DTP</scene>, <scene name='pdbligand=DUT:DEOXYURIDINE-5-TRIPHOSPHATE'>DUT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Guo, C.J]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8i0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8i0i OCA], [https://pdbe.org/8i0i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8i0i RCSB], [https://www.ebi.ac.uk/pdbsum/8i0i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8i0i ProSAT]</span></td></tr>
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[[Category: Liu, J.L]]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PYRG_DROME PYRG_DROME] Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides (By similarity). Isoform 1 is required for cytoophidium assembly in female germline cells.<ref>PMID:23459760</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Drosophila melanogaster]]
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[[Category: Large Structures]]
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[[Category: Guo CJ]]
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[[Category: Liu JL]]

Current revision

dmCTPS with dATP dUTP dGTP and DON

PDB ID 8i0i

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