Single-stranded DNA-binding protein
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* '''Viral SSB proteins''' are monomeric.<br /> | * '''Viral SSB proteins''' are monomeric.<br /> | ||
* '''Eukaryotic SSB''' ('''Replication protein A''' – RPA) is a heterotrimer composed of RPA70, RPA32 and RPA14. RPA has 6 DNA-binding domains (DBD).<br /> | * '''Eukaryotic SSB''' ('''Replication protein A''' – RPA) is a heterotrimer composed of RPA70, RPA32 and RPA14. RPA has 6 DNA-binding domains (DBD).<br /> | ||
| - | *'''Replication protein A70''' is the 70kDa subunit<ref>PMID:11470540</ref>. | + | *'''Replication protein A70''' is the eukaryotic SSB 70kDa subunit<ref>PMID:11470540</ref>. |
* '''Mitochondrial human SSB (HsmtSSB)''' is a homotetramer. | * '''Mitochondrial human SSB (HsmtSSB)''' is a homotetramer. | ||
Current revision
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References
- ↑ Marceau AH. Functions of single-strand DNA-binding proteins in DNA replication, recombination, and repair. Methods Mol Biol. 2012;922:1-21. doi: 10.1007/978-1-62703-032-8_1. PMID:22976174 doi:http://dx.doi.org/10.1007/978-1-62703-032-8_1
- ↑ Ishibashi T, Kimura S, Furukawa T, Hatanaka M, Hashimoto J, Sakaguchi K. Two types of replication protein A 70 kDa subunit in rice, Oryza sativa: molecular cloning, characterization, and cellular & tissue distribution. Gene. 2001 Jul 11;272(1-2):335-43. PMID:11470540 doi:10.1016/s0378-1119(01)00555-8