ABC transporter 3D structures

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Line 14: Line 14:
***[[4h5f]] - SpABC amino acid transporter + arginine - ''Streptococcus pneumoniae'' <br />
***[[4h5f]] - SpABC amino acid transporter + arginine - ''Streptococcus pneumoniae'' <br />
**[[6ggp]] - TmABC amino acid transporter – ''Thermotoga maritima'' <br />
**[[6ggp]] - TmABC amino acid transporter – ''Thermotoga maritima'' <br />
 +
**[[6gpm]] - TmABC amino acid transporter domain 2 115-206<br />
**[[6gpc]], [[6ggv]] - TmABC amino acid transporter + arginine <br />
**[[6gpc]], [[6ggv]] - TmABC amino acid transporter + arginine <br />
 +
**[[6q3u]], [[6svf]], [[7a99]] - TmABC amino acid transporter (mutant) + arginine <br />
 +
**[[6y16]] - TmABC amino acid transporter + guanidinium <br />
 +
**[[8hqr]] - ABC amino acid transporter + arginine – ''Candidatus pelagibacter''<br />
**Branched amino acid ABC transporter
**Branched amino acid ABC transporter
Line 38: Line 42:
**Glutamine ABC transporter
**Glutamine ABC transporter
-
***[[4kpt]], [[4kr5]], [[4la9]] - LlABC glutamine transporter – ''Lactococcus lactis''<br />
+
***[[4kpt]], [[4kr5]], [[4la9]], [[6h30]] - LlABC glutamine transporter – ''Lactococcus lactis''<br />
***[[4kqp]] - LlABC glutamine transporter + glutamine<br />
***[[4kqp]] - LlABC glutamine transporter + glutamine<br />
 +
**[[8hnj]] - EcABC glutamine transporter + glutamine<br />
 +
 +
**Asparagine ABC transporter
 +
 +
***[[6fxg]] - LlABC asparaine transporter + asparagine<br />
**Methionine ABC transporter
**Methionine ABC transporter
Line 49: Line 58:
***[[3dhx]] - EcABC methionine transporter C2 domain<br />
***[[3dhx]] - EcABC methionine transporter C2 domain<br />
***[[2qrr]] - ABC methionine transporter soluble domain - ''Vibrio parahaemolyticus'' <br />
***[[2qrr]] - ABC methionine transporter soluble domain - ''Vibrio parahaemolyticus'' <br />
 +
**[[7mc0]] - NmABC methionine transporter – ''Neisseria meningitides'' – Cryo EM<br />
 +
**[[7mbz]] - NmABC methionine transporter + lipoprotein – Cryo EM<br />
**Alanine ABC transporter
**Alanine ABC transporter
Line 74: Line 85:
***[[3o6p]] - EfABC amino acids transporter<br />
***[[3o6p]] - EfABC amino acids transporter<br />
***[[3ip9]] – AtABC amino acid transporter+GABA<br />
***[[3ip9]] – AtABC amino acid transporter+GABA<br />
-
**[[4z9n]] - ABC amino acid transporter+ glutathione – ''Brucella ovis''<br />
+
***[[7n5a]], [[7n5b]] - AtABC amino acid transporter family 25 + ADP – Cryo EM <br />
-
**[[6gpm]], [[6gpd]] - TmABC amino acid transporter <br />
+
***[[7n59]] - AtABC amino acid transporter family 25 + glutathione – Cryo EM <br />
 +
***[[4z9n]] - ABC amino acid transporter+ glutathione – ''Brucella ovis''<br />
 +
***[[6gpm]], [[6gpd]] - TmABC amino acid transporter <br />
**Cationic amino acid ABC transporter
**Cationic amino acid ABC transporter
***[[2m8c]] - EcABC amino acids transporter<br />
***[[2m8c]] - EcABC amino acids transporter<br />
 +
 +
*Dipeptide ABC transporter Dppa
 +
 +
**[[1hi9]] - BsABC Dppa – ''Bacillus subtilis''<br />
 +
**[[6e3d]], [[6e4d]] - MtABC Dppa + peptide - ''Mycobacterium tuberculosis''<br />
 +
**[[6pu3]], [[6ofq]] - HpABC Dppa – ''Helicobacter pylori''<br />
 +
**[[1dpe]] - EcABC Dppa<br />
 +
**[[4qfk]] - PsABC Dppa - ''Pseudoalteromonas'' <br />
 +
**[[4qfl]], [[4qfn]], [[4qfo]]. [[4qfp]] - PsABC Dppa + dipeptide <br />
 +
**[[4fwi]] - ABC Dppa NBD + ATP – ''Thermoanaerobacter tengcongensis''<br />
**Oligopeptide ABC transporter or oligopeptide-binding protein
**Oligopeptide ABC transporter or oligopeptide-binding protein
 +
***[[1rkm]] – StOpp – ''Salmonella typhimurium''<br />
 +
***[[3fto]] - LlOpp – ''Lactococcus lactis''<br />
 +
***[[2wol]] - ScOpp – ''Streptomyces clavuligerus''<br />
***[[3i5o]], [[1vr5]] - TmABC oligopeptides transporter <br />
***[[3i5o]], [[1vr5]] - TmABC oligopeptides transporter <br />
-
***[[4gl8]] - BbABC oligopeptide transporter + peptide<br />
 
***[[4ikv]], [[4ikw]] - GkABC oligopeptides transporter – ''Geobacillus kaustophilus''<br />
***[[4ikv]], [[4ikw]] - GkABC oligopeptides transporter – ''Geobacillus kaustophilus''<br />
***[[4ikx]], [[4iky]] - GkABC oligopeptides transporter (mutant)<br />
***[[4ikx]], [[4iky]] - GkABC oligopeptides transporter (mutant)<br />
-
***[[4ikz]] - GkABC oligopeptides transporter (mutant) + alafosfalin<br />
+
**[[4jso]] - TmABC oligopeptides transporter + laminaripentaose<br />
-
***[[2d5w]] - TtABC oligopeptide transporter + peptide<br />
+
***[[4gf8]], [[4gfr]] - VcABC oligopeptide transporter – ''Vibrio cholera''<br />
***[[4gf8]], [[4gfr]] - VcABC oligopeptide transporter – ''Vibrio cholera''<br />
***[[5yqw]] - ABC oligopeptide transporter – ''Vibrio harveyi''<br />
***[[5yqw]] - ABC oligopeptide transporter – ''Vibrio harveyi''<br />
-
**[[6npo]] - ABC oligopeptide transporter + peptide – ''Bacillus anthracis''<br />
+
 
 +
**Oligopeptide-binding protein complex with polypeptide
 +
 
 +
***[[1ola]], [[1olc]] – StOpp + tetrapeptide<br />
 +
***[[2olb]], [[1jet]], [[1jeu]], [[1jev]], [[1b1h]], [[1b3f]], [[1b3g]], [[1b3l]], [[1b32]], [[1b40]], [[1b46]], [[1b4z]], [[1b5i]], [[1b5j]], [[1b51]], [[1b52]], [[1b58]], [[1b9j]], [[1b0h]], [[1b05]], [[1qka]], [[1qkb]] - StOpp + tripeptide<br />
 +
***[[2rkm]] - StOpp + dipeptide<br />
 +
***[[1b4h]] - StOpp + Lys-DAB-Lys<br />
 +
***[[1b5h]] - StOpp + Lys-DPP-Lys<br />
 +
***[[1b6h]] - StOpp + Lys-NVA-Lys<br />
 +
***[[1b7h]] - StOpp + Lys-NLE-Lys<br />
 +
***[[1b2h]] - StOpp + Lys-ORN-Lys<br />
 +
***[[1b1h]] - StOpp + Lys-HPE-Lys<br />
 +
***[[1b3h]] - StOBpp+ Lys-ALC-Lys<br />
 +
***[[2z23]] - Opp + tripeptide – ''Yersinia pestis''<br />
 +
***[[3drf]], [[3dri]] - LlOpp + octapeptide<br />
 +
***[[3rya]], [[3ryb]] - LlOpp + nonapeptide<br />
 +
***[[3drg]] - LlOpp + bradykinin peptide<br />
 +
***[[3drh]] - LlOpp + hexapeptide<br />
 +
***[[3drj]] - LlOpp + PTH-related peptide<br />
 +
***[[3drk]] - LlOpp + neuropeptide S<br />
 +
***[[2wok]] - ScOpp + bradykinin peptide <br />
 +
***[[2wop]] - ScOpp + arginine<br />
 +
***[[1xoc]] - OPP + nonapeptide – ''Bacillus subtilis''<br />
 +
***[[3tcf]], [[3tcg]], [[3tch]] - OPP + peptide – ''Escherichia coli''<br />
 +
***[[3zs6]] - OPP + peptide – ''Burkholderia pseudomallei''<br />
 +
***[[6dqq]], [[6dqr]], [[6dqt]], [[6dqu]], [[6dtf]], [[6dtg]], [[6dth]] - OPP + peptide – ''Haemophilus influenzae''<br />
 +
***[[4gl8]] - BbABC oligopeptide transporter + peptide<br />
 +
***[[4ikz]] - GkABC oligopeptides transporter (mutant) + alafosfalin<br />
 +
***[[2d5w]] - TtABC oligopeptide transporter + peptide<br />
 +
***[[6npo]] - ABC oligopeptide transporter + peptide – ''Bacillus anthracis''<br />
* ABC sugar transporters
* ABC sugar transporters
 +
**[[6tha]] - hABC glucose transporter - human <br />
 +
**[[4pyp]] - hABC glucose transporter (mutant) <br />
 +
**[[4ybq]] - ABC glucose transporter - rat<br />
 +
**[[5ctg]], [[5cth]] - ABC sugar transporter - rice<br />
 +
**[[5uhq]], [[5uhs]] - ABC sugar transporter (mutant) – ''Leptospira biflexa''<br />
**[[2vk2]] - EcABC galactofuranose transporter +galactofuranose<br />
**[[2vk2]] - EcABC galactofuranose transporter +galactofuranose<br />
**[[2w7y]] - SpABC sugar transporter+A-trisaccaride – ''Streptococcus pneumoniae''<br />
**[[2w7y]] - SpABC sugar transporter+A-trisaccaride – ''Streptococcus pneumoniae''<br />
Line 104: Line 162:
**[[2z8f]] - BlABC lacto-N-biose transporter SBD+lacto-N-tetraose<br />
**[[2z8f]] - BlABC lacto-N-biose transporter SBD+lacto-N-tetraose<br />
**[[3c6q]] - TmABC sugar transporter (mutant)+beta-xylopyranose<br />
**[[3c6q]] - TmABC sugar transporter (mutant)+beta-xylopyranose<br />
-
**[[2yyz]], [[2qvc]], [[2h3h]], [[2hpg]], [[2ghb]] - TmABC sugar transporter<br />
+
**[[2yyz]], [[2qvc]], [[2h3h]], [[2hpg]], [[2ghb]], [[7pu4]] - TmABC sugar transporter<br />
 +
**[[7qsq]] - TmABC ribose transporter N-terminal<br />
 +
**[[7qsp]] - TmABC ribose transporter C-terminal<br />
**[[2fn9]] - TmABC sugar transporter (mutant)<br />
**[[2fn9]] - TmABC sugar transporter (mutant)<br />
**[[2o7i]] - TmABC sugar transporter+cellobiose<br />
**[[2o7i]] - TmABC sugar transporter+cellobiose<br />
Line 117: Line 177:
**[[3l49]] - RsABC ribose transporter – ''Rhodobacter sphaeroides''<br />
**[[3l49]] - RsABC ribose transporter – ''Rhodobacter sphaeroides''<br />
**[[4joq]] - RsABC ribose transporter (mutant) <br />
**[[4joq]] - RsABC ribose transporter (mutant) <br />
 +
**[[7e7m]] - ABC ribose transporter + ribose – ''Streptococcus agalactiae'' <br />
 +
**[[7qsq]] - TmABC ribose transporter N-terminal<br />
 +
**[[7qsp]] - TmABC ribose transporter C-terminal<br />
**[[3rot]] - ABC sugar transporter – ''Legionella pneumophila''<br />
**[[3rot]] - ABC sugar transporter – ''Legionella pneumophila''<br />
**[[4kvf]] - ABC rhamnose transporter – ''Kribbella flavida''<br />
**[[4kvf]] - ABC rhamnose transporter – ''Kribbella flavida''<br />
Line 123: Line 186:
**[[5xpj]] - PpABC sugar transporter – ''Pseudomonas putida'' <br />
**[[5xpj]] - PpABC sugar transporter – ''Pseudomonas putida'' <br />
**[[5dvj]], [[5dvi]], [[5dvf]] - PpABC sugar transporter+ monosaccharide <br />
**[[5dvj]], [[5dvi]], [[5dvf]] - PpABC sugar transporter+ monosaccharide <br />
 +
**[[5xpd]] - ABC sugar transporter+ CMP – ''Arabidopsis thaliana''<br />
 +
**[[6m2l]] - ABC hexose transporter – ''Plasmodium falciparum''<br />
 +
**[[7cad]] – MsABC sugar transporter – ''Mycobacterium smegmatis'' – Cryo EM<br />
 +
**[[7c63]], [[7c69]] - TtABC sugar transporter <br />
 +
**[[7c6f]], [[7c6m]], [[7c6x]], [[7c6y]], [[7c6z]], [[7c1b]], [[7c70]], [[7c71]] - TtABC sugar transporter (mutant)<br />
 +
**[[7c0f]], [[7c0k]], [[7c0l]] - TtABC sugar transporter + UPG<br />
 +
**[[7c0o]], [[7c0r]], [[7c0s]], [[7c0t]], [[7c0u]], [[7c0v]], [[7c0w]], [[7c0x]], [[7c0y]], [[7c0z]], [[7c14]], [[7c15]], [[7c16]], [[7c19]] - TtABC sugar transporter (mutant) + UPG<br />
 +
**[[7c64]], [[7c66]], [[7c67]], [[7c68]] - TtABC sugar transporter + saccharide<br />
 +
**[[7c6f]], [[[7c6g]], [[7c6h]], [7c6i]], [[7c6j]], [[7c6k]], [[7c6l]], [[7c6n]], [[7c6r]], [[7c6t]], [[7c6v]], [[7c6w]], [[7c70]] - TtABC sugar transporter (mutant) + saccharide<br />
 +
**[[8wl5]] - EncABC sugar transporter – Enterobacter cloacae<br />
 +
**[[8wl7]], [[8wl9]], [[8wlb]] - EncABC sugar transporter + saccharide <br />
*ABC maltose transporter see [[Maltose-binding protein]]
*ABC maltose transporter see [[Maltose-binding protein]]
Line 134: Line 208:
** ABC cobalt transporters
** ABC cobalt transporters
-
***[[3gfo]] - ABC cobalt transporter – ''Clostridium perfringens''<br />
+
***[[3gfo]] - CpABC cobalt transporter – ''Clostridium perfringens''<br />
 +
***[[5x40]] - RcABC cobalt transporter + AMPPCP – ''Rhodobacter capsulatus''<br />
 +
***[[5x3x]], [[5x41]] - RcABC cobalt transporter + CbiM + CbiQ<br />
-
** ABC nickel transporters
+
** ABC nickel transporters or NikA
***[[3t66]] - BhABC nickel transporter (mutant)<br />
***[[3t66]] - BhABC nickel transporter (mutant)<br />
Line 142: Line 218:
***[[4ls3]] - HpABC nickel transporter + Ni<br />
***[[4ls3]] - HpABC nickel transporter + Ni<br />
***[[4inp]] - HpABC nickel transporter (mutant) + Ni<br />
***[[4inp]] - HpABC nickel transporter (mutant) + Ni<br />
-
 
+
***[[3e3k]] - EcABC nickel transporter<br />
-
** ABC tungsten transporters
+
***[[1uiu]], [[3qim]] - EcABC nickel transporter (mutant) <br />
-
 
+
***[[3dp8]], [[4i8c]] - EcABC nickel transporter + Ni<br />
-
***[[3lr1]] - ABC tungstate transporter – ''Geobacter sulfurreducens''<br />
+
***[[1uiv]], [[2noo]] - EcABC nickel transporter (mutant) + Ni<br />
-
***[[2onk]] - AfABC molybdate/tungstate transporter+Mo/W binding protein – ''Archaeoglobus fulgidus''<br />
+
***[[5l8d]], [[5mwu]], [[6r4q]] - EcABC nickel transporter + Ru derivative<br />
-
***[[2onr]] - AfABC molybdate/tungstate transporter+Mo<br />
+
***[[1zlq]], [[3mvw]], [[3mvx]], [[3mvy]], [[3mvz]], [[3mw0]], [[3mz9]], [[3mzb]], [[4dcx]], [[4dcy]], [[4i9d]], [[5on0]], [[5on1]], [[5on4]], [[5on5]], [[5on8]], [[5on9]], [[7a0c]] - EcABC nickel transporter + Fe derivative<br />
-
***[[2ons]] - AfABC molybdate/tungstate transporter+W<br />
+
***[[8spm]] - EcABC nickel transporter + Asp derivative<br />
-
***[[4rxl]] - VcABC molybdate transporter + W<br />
+
***[[5yh5]] - SaABC nickel transporter <br />
 +
***[[4xkn]], [[4xkp]], [[4xkq]], [[4xkr]] - SaABC nickel transporter + Ni<br />
 +
***[[5yhe]] - SaABC nickel transporter + staphylopine + Co<br />
 +
***[[5yh8]] - SaABC nickel transporter + staphylopine + Ni<br />
 +
***[[5yhg]] - SaABC nickel transporter + staphylopine + Zn<br />
 +
***[[4oer]] - BsABC nickel transporter – ''Brucella suis''<br />
 +
***[[4oes]] - BsABC nickel transporter + Fe<br />
** ABC iron transporters
** ABC iron transporters
Line 160: Line 242:
***[[4h59]], [[4hmo]], [[4hmp]], [[4jcc]] - SpABC iron transporter <br />
***[[4h59]], [[4hmo]], [[4hmp]], [[4jcc]] - SpABC iron transporter <br />
***[[4hmq]] - SpABC iron transporter + ferrichrome<br />
***[[4hmq]] - SpABC iron transporter + ferrichrome<br />
 +
***[[3waf]], [[4elo]], [[4elp]], [[4elq]], [[7f6e]], [[7f6f]], [[7f6k]], [[7f6q]], [[7f6u]] - TtABC iron transporter <br />
 +
***[[7f6n]], [[7f6o]], [[7f6p]], [[7f6r]], [[7f6s]], [[7f6t]] - TtABC iron transporter (mutant)<br />
 +
***[[3wae]], [[4elr]] - TtABC iron transporter + Fe<br />
 +
***[[6j2s]] - ABC iron transporter + Ga – ''Pseudomonas aeruginosa''<br />
 +
***[[5jj5]] - SaABC iron transporter + Fe<br />
 +
***[[7li1]] - ABC iron transporter + Fe – ''Moraxella catarrhalis''<br />
 +
***[[8k7n]] - ABC iron transporter + Fe – ''Klebsiella pneumoniae''<br />
 +
 +
** ABC manganese transporters
 +
 +
***[[7kyp]] - SpABC manganese transporter <br />
 +
***[[7kyo]] - SpABC manganese transporter + antibody<br />
-
** ABC molybdenum transporters
+
** ABC molybdenum transporters or ModA
***[[3d31]] - MaABC sulfate/molybdate transporter – ''Methanosarcina acetivorans''<br />
***[[3d31]] - MaABC sulfate/molybdate transporter – ''Methanosarcina acetivorans''<br />
***[[3cfx]] - MaABC sulfate/molybdate transporter + WO4<br />
***[[3cfx]] - MaABC sulfate/molybdate transporter + WO4<br />
 +
***[[3k6u]], [[3k6v]] - MaABC molybdate transporter <br />
 +
***[[3k6w]], [[3k6x]] - MaABC molybdate transporter + Mo<br />
 +
***[[1amf]] - EcABC molybdate transporter + Mo<br />
 +
***[[1wod]] - EcABC molybdate transporter + WO4<br />
 +
***[[3axf]], [[3r26]] - EcABC molybdate transporter + Re<br />
 +
***[[4xxu]] - EcABC molybdate transporter + Cr<br />
***[[3cfz]] - MjABC sulfate/molybdate transporter + WO4<br />
***[[3cfz]] - MjABC sulfate/molybdate transporter + WO4<br />
***[[3cg1]] - ABC sulfate/molybdate transporter + WO4 – ''Pyrococcus furiosus''<br />
***[[3cg1]] - ABC sulfate/molybdate transporter + WO4 – ''Pyrococcus furiosus''<br />
***[[3cg3]] - PhABC sulfate/molybdate transporter + WO4<br />
***[[3cg3]] - PhABC sulfate/molybdate transporter + WO4<br />
 +
***[[3lr1]] - ABC tungstate transporter – ''Geobacter sulfurreducens''<br />
 +
***[[2onk]] - AfABC molybdate/tungstate transporter+Mo/W binding protein – ''Archaeoglobus fulgidus''<br />
 +
***[[2onr]] - AfABC molybdate/tungstate transporter+Mo<br />
 +
***[[2ons]] - AfABC molybdate/tungstate transporter+WO4<br />
 +
***[[4rxl]] - VcABC molybdate transporter + WO4<br />
 +
***[[2h5y]], [[3gzg]] - ABC molybdate transporter + Mo – ''Xanthomonas citri''<br />
 +
***[[6nio]] - ABC molybdate transporter – ''Yersinia pestis''<br />
 +
***[[1atg]] - ABC molybdate transporter + Mo – ''Azotobacter vinelandii''<br />
 +
***[[7tav]] - ABC molybdate transporter – ''Listeria monocytogenes''<br />
** ABC zinc transporters
** ABC zinc transporters
***[[2ogw]] - EcABC zinc transporter<br />
***[[2ogw]] - EcABC zinc transporter<br />
-
***[[2xh8]] - SeABC zinc transporter (mutant) – ''Salmonella enterica''<br />
+
***[[2xy4]] - SeABC zinc transporter – ''Salmonella enterica''<br />
 +
***[[2xh8]] - SeABC zinc transporter (mutant) <br />
***[[2xqv]] - SeABC zinc transporter + Zn<br />
***[[2xqv]] - SeABC zinc transporter + Zn<br />
-
***[[2xy4]] - SeABC zinc transporter<br />
+
***[[4bbp]] - SeABC zinc transporter + inhibitor + Zn<br />
***[[2ov3]], [[2ov1]], [[1pq4]] - SsABC zinc transporter – ''Synechocystis''<br />
***[[2ov3]], [[2ov1]], [[1pq4]] - SsABC zinc transporter – ''Synechocystis''<br />
* ABC multidrug transporters
* ABC multidrug transporters
 +
**[[6ffc]] – hABCG2 multidrug transporter + inhibitor – Cryo EM<br />
 +
**[[5nj3]] – hABCG2 multidrug transporter (mutant) + antibody – Cryo EM<br />
 +
**[[6hbu]] – hABCG2 multidrug transporter (mutant) + ATP – Cryo EM<br />
 +
**[[6hco]] – hABCG2 multidrug transporter (mutant) + antibody + estrone sulfate – Cryo EM<br />
 +
**[[7p03]], [[7p05]], [[7p04]], [[7p06]] - yABC multidrug transporter + ATP + ADP – Cryo EM<br />
**[[2onj]] - SaABC multidrug transporter+AMP-PNP<br />
**[[2onj]] - SaABC multidrug transporter+AMP-PNP<br />
**[[2hyd]] - SaABC multidrug transporter<br />
**[[2hyd]] - SaABC multidrug transporter<br />
-
**[[1mv5]] - LlABC multidrug transporter ATP binding domain
+
**[[1mv5]] - LlABC multidrug transporter ATP binding domain <brt />
 +
**[[5mkk]] - TtABC multidrug transporter ATP binding domain <br />
 +
**[[6ran]] - TtABC multidrug transporter ATP binding domain + nanobody – Cryo EM<br />
 +
**[[6rag]], [[6rah]], [[6rai]], [[6raj]], [[6rak]], [[6ral]], [[6ram]] - TtABC multidrug transporter ATP binding domain + nanobody + ATP – Cryo EM<br />
 +
**[[6raf]] - TtABC multidrug transporter ATP binding domain + VHH + ATP + ADP – Cryo EM<br />
 +
**[[7ow8]] - BsABC multidrug transporter ATP binding domain + ATP – Cryo EM<br />
 +
**[[7bg4]] - BsABC multidrug transporter ATP binding domain + rhodamine + ATP – Cryo EM<br />
-
* ABC choline transporters
+
* ABC choline transporters or Glycine etaine/carnitine/choline ABC transporters
**[[3hcq]] - SmABC choline transporter (mutant) – ''Sinorhizobium meliloti''<br />
**[[3hcq]] - SmABC choline transporter (mutant) – ''Sinorhizobium meliloti''<br />
Line 189: Line 310:
**[[2reg]] - SmABC choline transporter (mutant)+choline<br />
**[[2reg]] - SmABC choline transporter (mutant)+choline<br />
**[[2rej]], [[2rf1]] - SmABC choline transporter (mutant)<br />
**[[2rej]], [[2rf1]] - SmABC choline transporter (mutant)<br />
-
**[[3o66]] – SaABC choline transporter
+
**[[3o66]] – SaABC choline transporter<br />
 +
**[[3chg]], [[3ppn]], [[3ppo]], [[3ppp]], [[3ppr]] - BsABC OpuAC choline transporter <br />
 +
**[[3ppq]], [[3r6u]] - BsABC OpuBC choline transporter + choline<br />
 +
**[[6eyq]] - BsABC OpuBC choline transporter (mutant) + choline<br />
 +
**[[5nxx]] - BsABC OpuAC choline transporter + arsenobetaine<br />
 +
**[[2b4l]], [[6eyh]] - BsABC OpuAC choline transporter + glycine betaine<br />
 +
**[[2b4m]] - BsABC OpuAC choline transporter + proline betaine<br />
 +
**[[3l6g]], [[3l6h]] – LlABC OpuAC betaine transporter SBD<br />
-
* ABC α-hemolysin transporters
+
* ABC α-hemolysin transporters or alpha-hemolysin translocation ATP-binding protein
 +
**[[3zua]] - EcABC alpha-hemolysin transporter C39-like domain – NMR<br />
**[[2pmk]] - EcABC α-hemolysin transporter NBD+TNP-ADP<br />
**[[2pmk]] - EcABC α-hemolysin transporter NBD+TNP-ADP<br />
**[[2ff7]] - EcABC α-hemolysin transporter NBD+ADP<br />
**[[2ff7]] - EcABC α-hemolysin transporter NBD+ADP<br />
Line 198: Line 327:
**[[2fgj]], [[2fgk]], [[1xef]] - EcABC α-hemolysin transporter NBD (mutant)+ATP<br />
**[[2fgj]], [[2fgk]], [[1xef]] - EcABC α-hemolysin transporter NBD (mutant)+ATP<br />
**[[3b5j]] - EcABC α-hemolysin transporter (mutant) NBD+TNP-ADP<br />
**[[3b5j]] - EcABC α-hemolysin transporter (mutant) NBD+TNP-ADP<br />
 +
 +
*ATP-binding transport protein MsbA
 +
 +
**[[3bk7]] – ABC ATP-binding – ''Pyrococcus abyssi''
 +
**[[8tsl]], [[8tsw]], [[8tt3]], [[8tun]] – CtABC ATP-binding + transport permease + capsular biosynthesis protein – ''Caldimonas thermodepolymerans'' – Cryo EM<br />
 +
**[[8tsh]] – CtABC ATP-binding + transport permease + capsular biosynthesis protein + ATP – Cryo EM<br />
 +
**[[8fef]] – MsABC ATP-binding MCE1 – Cryo EM<br />
 +
**[[7d08]], [[7d09]] – AbABC ATP-binding + MLAE + anti-sigma factor antagonist + MCE family protein – Cryo EM<br />
 +
**[[8dmm]], [[8tsp]], [[8tsq]] – EcMsbA – Cryo EM<br />
* ABC various compounds transporters
* ABC various compounds transporters
Line 206: Line 344:
**[[1l7v]] - EcABC vitamin B12 transporter+BtuD<br />
**[[1l7v]] - EcABC vitamin B12 transporter+BtuD<br />
**[[3p7i]], [[3qk6]], [[3quj]], [[3s4u]] – EcABC alkylphosphonate transporter PHND + aminoethyl phosphonic acid<br />
**[[3p7i]], [[3qk6]], [[3quj]], [[3s4u]] – EcABC alkylphosphonate transporter PHND + aminoethyl phosphonic acid<br />
 +
**[[7s6g]] - SsABC phosphonate transporter + PO4<br />
 +
**[[7s6e]] - SsABC urea transporter + urea<br />
**[[1twy]] - VcABC phosphate transporter <br />
**[[1twy]] - VcABC phosphate transporter <br />
**[[4n13]] - BbABC phosphate transporter (mutant)<br />
**[[4n13]] - BbABC phosphate transporter (mutant)<br />
-
**[[3l6g]], [[3l6h]] – LlABC OpuAC betaine transporter SBD <br />
+
**[[4exl]] - SpABC phosphate transporter<br />
 +
**[[4q8r]] - CpABC phosphate transporter + PO4<br />
**[[2zzv]] - TtABC solute transporter+lactate+Ca<br />
**[[2zzv]] - TtABC solute transporter+lactate+Ca<br />
**[[2zzw]] - TtABC solute transporter+lactate+Zn<br />
**[[2zzw]] - TtABC solute transporter+lactate+Zn<br />
**[[2zzx]] - TtABC solute transporter+lactate<br />
**[[2zzx]] - TtABC solute transporter+lactate<br />
-
**[[3gfv]] - BsABC petrobactin transporter – ''Bacillus subtilis''<br />
+
**[[3gfv]] - BsABC petrobactin transporter <br />
-
**[[3bk7]] – ABC ATP-binding – ''Pyrococcus abyssi''<br />
+
-
**[[3ppn]] - BsABC multiple solute transporter<br />
+
-
**[[3ppo]], [[3ppp]], [[3ppq]], [[3ppr]] - BsABC multiple solute transporter + solute<br />
+
**[[3hn0]] – ABC NO3 transporter – ''Parabacteroides distasonis''<br />
**[[3hn0]] – ABC NO3 transporter – ''Parabacteroides distasonis''<br />
**[[3rlb]] - LlABC vitamin B1 transporter + thiamin<br />
**[[3rlb]] - LlABC vitamin B1 transporter + thiamin<br />
**[[4dve]] - LlABC biotin transporter + biotin<br />
**[[4dve]] - LlABC biotin transporter + biotin<br />
**[[3uif]] – ABC sulfonate transporter – ''Methylobacillus flagellates''<br />
**[[3uif]] – ABC sulfonate transporter – ''Methylobacillus flagellates''<br />
-
**[[4mfi]] – ABC glycerol phosphate transporter – ''Mycobacterium tuberculosis''<br />
+
**[[4mfi]] – MtABC glycerol phosphate transporter<br />
**[[2q6h]] – AaABC serotonin transporter - ''Aquifex aeolicus''<br />
**[[2q6h]] – AaABC serotonin transporter - ''Aquifex aeolicus''<br />
**[[6oih]], [[6an5]], [[6amx]] – AaABC O-antigen polysaccharide transporter <br />
**[[6oih]], [[6an5]], [[6amx]] – AaABC O-antigen polysaccharide transporter <br />
 +
**[[6m96]] – AaABC O-antigen polysaccharide transporter + ATP<br />
 +
**[[7k2t]] – AaABC O-antigen polysaccharide transporter + ATP – Cryo EM<br />
 +
**[[8dky]] – AaABC O-antigen polysaccharide transporter <br />
 +
**[[8dku]], [[8dl0]], [[8dn8]] – AaABC O-antigen polysaccharide transporter + transport permease protein – Cryo EM<br />
 +
**[[8dnc]] – AaABC O-antigen polysaccharide transporter + transport permease protein + ATP – Cryo EM<br />
**[[6hnp]] – ABC O-antigen polysaccharide transporter – ''Raoultella ornithinolytica''<br />
**[[6hnp]] – ABC O-antigen polysaccharide transporter – ''Raoultella ornithinolytica''<br />
* hABC transporters subfamilies
* hABC transporters subfamilies
 +
**[[7roq]], [[7tby]], [[7tc0]] – hABCA1 + cholesterol – Cryo EM<br />
 +
**[[7tbz]] – hABCA1 (mutant) + cholesterol – Cryo EM<br />
 +
**[[7tbw]] – hABCA1 (mutant) + cholesterol + ATP – Cryo EM<br />
 +
**[[7e7i]], [[7e7o]], [[7lkp]], [[7m1p]], [[7m1q]] – hABCA4 – Cryo EM<br />
 +
**[[7e7q]], [[7lkz]] – hABCA4 + ATP – Cryo EM<br />
 +
**[[8f5b]] – hABCA4 + AMPPNP – Cryo EM<br />
 +
**[[8edw]], [[8ee6]], [[8eeb]] – hABCA7 – Cryo EM<br />
 +
**[[8fwk]] – hABCB6 – Cryo EM<br />
 +
**[[7ekl]], [[8k7b]] – hABCB6 (mutant) – Cryo EM<br />
**[[3nh6]] – hABCB6 NBD<br />
**[[3nh6]] – hABCB6 NBD<br />
**[[3nhb]] – hABCB6 NBD+ADP<br />
**[[3nhb]] – hABCB6 NBD+ADP<br />
**[[3nh9]] – hABCB6 NBD+ATP<br />
**[[3nh9]] – hABCB6 NBD+ATP<br />
-
**[[3nha]] – hABCB6 NBD+ATP+Mg
+
**[[3nha]] – hABCB6 NBD+ATP+Mg <br />
 +
**[[8yr3]], [[8yr4]] – hABCB6 + glutathione – Cryo EM<br />
 +
**[[8k7c]] – hABCB6 (mutant) + ADP – Cryo EM<br />
 +
**[[7vgf]] – hABCB7 (mutant) + AMPPNP – Cryo EM<br />
 +
**[[7y49]] – hABCB10 – Cryo EM<br />
 +
**[[7y48]] – hABCB10 (mutant) + cholesterol + biliverdine – Cryo EM<br />
 +
**[[8jx7]], [[8jy4]], [[8jy5]] – hABCC2 – Cryo EM<br />
 +
**[[8jxu]] – hABCC2 + ADP + ATP – Cryo EM<br />
 +
**[[8jxq]] – hABCC2 + cholesterol + bilirubine – Cryo EM<br />
 +
**[[8hvh]] – hABCC3 – Cryo EM<br />
 +
**[[8hw2]], [[8hw4]] – hABCC3 + hormone – Cryo EM<br />
 +
**[[8i4b]], [[8i4c]], [[8iz8]], [[8xok]] – hABCC4 – Cryo EM<br />
 +
**[[8i4a]] – hABCC4 + dipyridamole – Cryo EM<br />
 +
**[[8bwr]], [[8iz9]] – hABCC4 + prostaglandin – Cryo EM<br />
 +
**[[8bjf]] – hABCC4 + cholesterol – Cryo EM<br />
 +
**[[8bwp]], [[8bwq]], [[8iz7]], [[8j3w]]] – hABCC4 + drug – Cryo EM<br />
 +
**[[8xom]]] – hABCC4 + drug + ANP – Cryo EM<br />
 +
**[[8iza]], [8j3z]] – hABCC4 + ATP – Cryo EM<br />
 +
**[[8bwo]] – hABCC4 (mutant) + ATP – Cryo EM<br />
 +
**[[8xol]] – hABCC8 + ANP – Cryo EM<br />
 +
**[[5ywd]] – hABCC8 + ADP – Cryo EM<br />
 +
**[[7s5v]] – hABCC8 + ADP + ATP – Cryo EM<br />
 +
**[[7s5x]], [[7s5y]], [[7s5z]], [[7s60]], [[7s61]], [[7w4o]] – hABCC8 + potassium channel + ADP + ATP – Cryo EM<br />
 +
**[[7rr9]], [[7rra]], [[7vwc]], [[7yrq]] – hABCD1 – Cryo EM<br />
 +
**[[7shn]], [[7vzb]] – hABCD1 + CoA derivative – Cryo EM<br />
 +
**[[7vx8]], [[7shm]] – hABCD1 + ATP – Cryo EM<br />
 +
**[[7r8d]], [[7fd7]] – hABCG1 + cholesterol – Cryo EM<br />
 +
**[[7dny]] – hABCG1 + coproporphyrin – Cryo EM<br />
 +
**[[7oz1]], [[7r8e]] – hABCG1 (mutant) + cholesterol + ATP – Cryo EM<br />
 +
**[[7a65]] – hABCG1 + antibody + cholesterol – Cryo EM<br />
 +
**[[7o9w]] – hABCG1 + drug + antibody – Cryo EM<br />
 +
**[[7a69]], [[7a6c]], [[7a6e]], [[7a6f]] – hABCG1 + drug + antibody + cholesterol – Cryo EM<br />
 +
**[[7ojh]] – hABCG2 + drug – Cryo EM<br />
 +
**[[7oji]] – hABCG2 + drug + cholesterol – Cryo EM<br />
 +
**[[8u2c]] – hABCG2 + antibody – Cryo EM<br />
 +
**[[5njg]] – hABCG2 (mutant) + antibody – Cryo EM<br />
 +
**[[7neq]], [[7nez]], [[7nfd]] – hABCG2 + drug + antibody – Cryo EM<br />
 +
**[[7niu]] – hABCG4 + antibody + cholesterol – Cryo EM<br />
 +
**[[7niv]] – hABCG4 + antibody + cholesterol + phosphatidylcholine – Cryo EM<br />
 +
**[[7niw]] – hABCG4 + antibody + cholesterol + drug – Cryo EM<br />
 +
**[[7d7n]], [[7d7r]], [[7ekm]] – hABCG6 core domain – Cryo EM<br />
 +
**[[7dnz]] – hABCG6 + glutathione + drug – Cryo EM<br />
 +
**[[7r87]], [[7r88]], [[7r89]] – hABCG5 + hABCG6 + antibody – Cryo EM<br />
 +
**[[7r8b]] – hABCG5 + hABCG6 + antibody + cholesterol – Cryo EM<br />
 +
**[[7jr7]], [[7r8a]] – hABCG5 + hABCG8 + antibody + cholesterol – Cryo EM<br />
 +
**[[5do7]] – hABCG5 sterol transporter + hABCG8 <br />
 +
 
 +
*Non-human ABC transporters subfamilies
 +
 
 +
**[[7v5d]] – mABCB9 – Cryo EM<br />
 +
**[[7v5c]] – mABCB9 + ADP – Cryo EM<br />
 +
**[[7vfi]] – mABCB9 + peptide – Cryo EM<br />
 +
**[[8woi]] – AtABCB19 – Cryo EM<br />
 +
**[[8wom]] – AtABCB19 + plant hormone – Cryo EM<br />
 +
**[[8woo]] – AtABCB19 + plant hormone + AMP-PNP – Cryo EM<br />
 +
**[[8wp0]] – AtABCB19 (mutant) + ATP – Cryo EM<br />
 +
**[[7n58]] – AtABCB25 – Cryo EM<br />
 +
**[[7vlr]] – rABCC9 + ADP + ATP – Cryo EM<br />
 +
**[[7vls]], [[7vlt]], [[7vlu]] – rABCC9 + drug + ADP + ATP – Cryo EM<br />
 +
**[[7oti]] – mABCG1A – Cryo EM<br />
 +
**[[7otg]] – mABCG1A + drug – Cryo EM<br />
 +
**]]8i38]], [[8i3c]], [[8i3d]], [[8iwj]], [[8k0z]], [[8wd6]] – AtABCG25 – Cryo EM<br />
 +
**[[8wba]] – AtABCG25 + cholesterol – Cryo EM<br />
 +
**[[8i3a]], [[8i3b]], [[8iwn]], [[8wam]] – AtABCG25 (mutant) + ATP – Cryo EM<br />
 +
**[[8i39]], [[8iwk]], [[8k0x]], [[8wbx]] – AtABCG25 + abscisic acid derivative – Cryo EM<br />
 +
 
 +
*Lipoprotein-release ABC transporter LolCDE
 +
 
 +
**[[7ari]], [[7mdx]] – EcLolC + LolD + LolE – Cryo EM<br />
 +
**[[7ark]], [[7mdy]] – EcLolC + LolD + LolE + nucleotide – Cryo EM<br />
 +
**[[7arj]], [[7arl]] – EcLolC + LolD + LolE + lipoprotein + nucleotide – Cryo EM<br />
 +
**[[7arh]] – EcLolC + LolD + LolE + lipoprotein – Cryo EM<br />
 +
**[[7arm]] – EcLolC + LolD + LolE + lipoprotein + LolA – Cryo EM<br />
 +
**[[5naa]] – EcLolC<br />
 +
**[[6f49]] – EcLolC periplasmic domain <br />
 +
**[[6f3z]] – EcLolC periplasmic domain + LolA<br />
 +
**[[2pcj]], [[2pcl]] – AaLolD <br />
 +
**[[5udf]] – LolE N-terminal – ''Acinetobacter baumannii<''br />
 +
 
 +
*Cobalamin ABC transporter
 +
 
 +
**[[8c7p]] – TdABC – ''Thiobacillus denitrificans''<br />
 +
**[[8ovv]] – TdABC + hydroxycobalamin<br />
* ABC unspecified transporters
* ABC unspecified transporters
Line 244: Line 478:
**[[4ayt]], [[3zdq]], [[4ayt]], [[4ayw]], [[4ayx]] - hABC transporter B 10<br />
**[[4ayt]], [[3zdq]], [[4ayt]], [[4ayw]], [[4ayx]] - hABC transporter B 10<br />
**[[4g68]] – ABC transporter - ''Caldanaerobius''<br />
**[[4g68]] – ABC transporter - ''Caldanaerobius''<br />
-
**[[4wwh]] – ABC transporter + galactose – ''Mycobacterium smegmatis''<br />
+
**[[4wwh]] – MsABC transporter + galactose <br />
 +
**[[8bnw]] - PtABC transporter – ''Parageobacillus thermoglucosidasius''<br />
 +
**[[8bf6]] - PtABC transporter + siderophore<br />
-
* Cystic fibrosis transmembrane conductance regulator (CFTR)
+
* Cystic fibrosis transmembrane conductance regulator (CFTR) or hABCC7; Domains – NBD1 387-646; NBD2 – 1202-1430
 +
**[[5uak]] – hCFTR – Cryo EM <br />
 +
**[[8ej1]] – hCFTR (mutant) – Cryo EM <br />
**[[6o2p]], [[6o1v]] – hCFTR + peptide – Cryo EM <br />
**[[6o2p]], [[6o1v]] – hCFTR + peptide – Cryo EM <br />
**[[6msm]] – hCFTR + peptide + cholesterol + ATP – Cryo EM <br />
**[[6msm]] – hCFTR + peptide + cholesterol + ATP – Cryo EM <br />
-
**[[3gd7]] – hCFTR/malK+N6-phenylethyl-ATP<br />
+
**[[7svr]] – hCFTR + drug – Cryo EM <br />
-
**[[2pze]], [[2pzf]], [[2pzg]], [[5uak]] – hCFTR NBD1<br />
+
**[[8eig]] – hCFTR (mutant) + drug – Cryo EM <br />
-
**[[2bbo]], [[2bbs]], [[2bbt]] - hCFTR NBD1 (mutant)<br />
+
**[[8fzq]] – hCFTR + ATP – Cryo EM <br />
-
**[[1xmi]], [[2xmj]], [[1xmj]], [[5tf7]], [[5tf8]], [[5tfa]], [[5tfb]], [[5tfc]], [[5tfd]], [[5tff]], [[5tfg]], [[5tfi]], [[5tfj]], [[4wz6]], [[5tgk]] - hCFTR NBD1 (mutant)+ nucleotide<br />
+
**[[8v7z]] – hCFTR (mutant) + ATP – Cryo EM <br />
-
**[[6gkd]], [[6gk4]], [[6gju]], [[6gjs]], [[6gjq]] - hCFTR NBD1 (mutant) + antibody<br />
+
**[[7sv7]], [[7svd]], [[8eio]], [[8eiq]] – hCFTR + drug + ATP – Cryo EM <br />
-
**[[1xf9]], [[2xfa]], [[1xfa]], [[3si7]] - mCFTR NBD1 (mutant) - mouse<br />
+
**[[8ubr]], [[8v81]] – hCFTR + inhibitor + ATP – Cryo EM <br />
-
**[[1q3h]] - mCFTR NBD1+AMPPNP<br />
+
**[[8gls]] – hCFTR + modulator – Cryo EM <br />
-
**[[1r0w]] - mCFTR NBD1<br />
+
**[[3gd7]] – hCFTR/malK+N6-phenylethyl-ATP
-
**[[1r0x]], [[1r0z]], [[1r10]] - mCFTR NBD1+ATP<br />
+
**[[2pze]], [[2pzf]], [[2pzg]] – hCFTR NBD1
-
**[[1r0y]] - mCFTR NBD1+ADP<br />
+
**[[2bbo]], [[2bbs]], [[2bbt]] - hCFTR NBD1 (mutant)
-
**[[1ckw]], [[1ckx]], [[1cky]], [[1ckz]] – CFTR F508 region - NMR<br />
+
**[[1xmi]], [[2xmj]], [[1xmj]], [[5tf7]], [[5tf8]], [[5tfa]], [[5tfb]], [[5tfc]], [[5tfd]], [[5tff]], [[5tfg]], [[5tfi]], [[5tfj]], [[4wz6]], [[5tgk]] - hCFTR NBD1 (mutant)+ nucleotide
 +
**[[6gkd]], [[6gk4]], [[6gju]], [[6gjs]], [[6gjq]] - hCFTR NBD1 (mutant) + antibody<br />
 +
**[[6uk1]] - hCFTR NBD2 (mutant) + ATP<br />
 +
**[[1xf9]], [[2xfa]], [[1xfa]], [[3si7]] - mCFTR NBD1 (mutant) - mouse
 +
**[[1q3h]] - mCFTR NBD1+AMPPNP
 +
**[[1r0w]] - mCFTR NBD1
 +
**[[1r0x]], [[1r0z]], [[1r10]]- mCFTR NBD1+ATP
 +
**[[1r0y]] - mCFTR NBD1+ADP
**[[6d3r]], [[6d3s]] - CFTR + ATP – chicken <br />
**[[6d3r]], [[6d3s]] - CFTR + ATP – chicken <br />
**[[5uar]] - zCFTR – zebrafish – Cryo EM<br />
**[[5uar]] - zCFTR – zebrafish – Cryo EM<br />
-
**[[5w81]] - zCFTR + ATP – Cryo EM<br /
+
**[[5w81]] - zCFTR + ATP – Cryo EM<br />
 +
 
}}
}}
[[Category: Topic Page]]
[[Category: Topic Page]]

Current revision

3D Structures of ABC transporter

Updated on 03-September-2024

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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