ABC transporter 3D structures

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Line 165: Line 165:
**[[7qsq]] - TmABC ribose transporter N-terminal<br />
**[[7qsq]] - TmABC ribose transporter N-terminal<br />
**[[7qsp]] - TmABC ribose transporter C-terminal<br />
**[[7qsp]] - TmABC ribose transporter C-terminal<br />
- 
**[[2fn9]] - TmABC sugar transporter (mutant)<br />
**[[2fn9]] - TmABC sugar transporter (mutant)<br />
**[[2o7i]] - TmABC sugar transporter+cellobiose<br />
**[[2o7i]] - TmABC sugar transporter+cellobiose<br />
Line 331: Line 330:
*ATP-binding transport protein MsbA
*ATP-binding transport protein MsbA
-
3bk7 – ABC ATP-binding – ''Pyrococcus abyssi''
+
**[[3bk7]] – ABC ATP-binding – ''Pyrococcus abyssi''
**[[8tsl]], [[8tsw]], [[8tt3]], [[8tun]] – CtABC ATP-binding + transport permease + capsular biosynthesis protein – ''Caldimonas thermodepolymerans'' – Cryo EM<br />
**[[8tsl]], [[8tsw]], [[8tt3]], [[8tun]] – CtABC ATP-binding + transport permease + capsular biosynthesis protein – ''Caldimonas thermodepolymerans'' – Cryo EM<br />
**[[8tsh]] – CtABC ATP-binding + transport permease + capsular biosynthesis protein + ATP – Cryo EM<br />
**[[8tsh]] – CtABC ATP-binding + transport permease + capsular biosynthesis protein + ATP – Cryo EM<br />
Line 355: Line 354:
**[[2zzx]] - TtABC solute transporter+lactate<br />
**[[2zzx]] - TtABC solute transporter+lactate<br />
**[[3gfv]] - BsABC petrobactin transporter <br />
**[[3gfv]] - BsABC petrobactin transporter <br />
-
**[[3bk7]] – ABC ATP-binding – ''Pyrococcus abyssi''<br />
 
**[[3hn0]] – ABC NO3 transporter – ''Parabacteroides distasonis''<br />
**[[3hn0]] – ABC NO3 transporter – ''Parabacteroides distasonis''<br />
**[[3rlb]] - LlABC vitamin B1 transporter + thiamin<br />
**[[3rlb]] - LlABC vitamin B1 transporter + thiamin<br />
Line 365: Line 363:
**[[6m96]] – AaABC O-antigen polysaccharide transporter + ATP<br />
**[[6m96]] – AaABC O-antigen polysaccharide transporter + ATP<br />
**[[7k2t]] – AaABC O-antigen polysaccharide transporter + ATP – Cryo EM<br />
**[[7k2t]] – AaABC O-antigen polysaccharide transporter + ATP – Cryo EM<br />
 +
**[[8dky]] – AaABC O-antigen polysaccharide transporter <br />
 +
**[[8dku]], [[8dl0]], [[8dn8]] – AaABC O-antigen polysaccharide transporter + transport permease protein – Cryo EM<br />
 +
**[[8dnc]] – AaABC O-antigen polysaccharide transporter + transport permease protein + ATP – Cryo EM<br />
**[[6hnp]] – ABC O-antigen polysaccharide transporter – ''Raoultella ornithinolytica''<br />
**[[6hnp]] – ABC O-antigen polysaccharide transporter – ''Raoultella ornithinolytica''<br />
Line 372: Line 373:
**[[7tbz]] – hABCA1 (mutant) + cholesterol – Cryo EM<br />
**[[7tbz]] – hABCA1 (mutant) + cholesterol – Cryo EM<br />
**[[7tbw]] – hABCA1 (mutant) + cholesterol + ATP – Cryo EM<br />
**[[7tbw]] – hABCA1 (mutant) + cholesterol + ATP – Cryo EM<br />
 +
**[[7e7i]], [[7e7o]], [[7lkp]], [[7m1p]], [[7m1q]] – hABCA4 – Cryo EM<br />
 +
**[[7e7q]], [[7lkz]] – hABCA4 + ATP – Cryo EM<br />
 +
**[[8f5b]] – hABCA4 + AMPPNP – Cryo EM<br />
 +
**[[8edw]], [[8ee6]], [[8eeb]] – hABCA7 – Cryo EM<br />
 +
**[[8fwk]] – hABCB6 – Cryo EM<br />
 +
**[[7ekl]], [[8k7b]] – hABCB6 (mutant) – Cryo EM<br />
**[[3nh6]] – hABCB6 NBD<br />
**[[3nh6]] – hABCB6 NBD<br />
**[[3nhb]] – hABCB6 NBD+ADP<br />
**[[3nhb]] – hABCB6 NBD+ADP<br />
**[[3nh9]] – hABCB6 NBD+ATP<br />
**[[3nh9]] – hABCB6 NBD+ATP<br />
**[[3nha]] – hABCB6 NBD+ATP+Mg <br />
**[[3nha]] – hABCB6 NBD+ATP+Mg <br />
 +
**[[8yr3]], [[8yr4]] – hABCB6 + glutathione – Cryo EM<br />
 +
**[[8k7c]] – hABCB6 (mutant) + ADP – Cryo EM<br />
 +
**[[7vgf]] – hABCB7 (mutant) + AMPPNP – Cryo EM<br />
 +
**[[7y49]] – hABCB10 – Cryo EM<br />
 +
**[[7y48]] – hABCB10 (mutant) + cholesterol + biliverdine – Cryo EM<br />
 +
**[[8jx7]], [[8jy4]], [[8jy5]] – hABCC2 – Cryo EM<br />
 +
**[[8jxu]] – hABCC2 + ADP + ATP – Cryo EM<br />
 +
**[[8jxq]] – hABCC2 + cholesterol + bilirubine – Cryo EM<br />
 +
**[[8hvh]] – hABCC3 – Cryo EM<br />
 +
**[[8hw2]], [[8hw4]] – hABCC3 + hormone – Cryo EM<br />
 +
**[[8i4b]], [[8i4c]], [[8iz8]], [[8xok]] – hABCC4 – Cryo EM<br />
 +
**[[8i4a]] – hABCC4 + dipyridamole – Cryo EM<br />
 +
**[[8bwr]], [[8iz9]] – hABCC4 + prostaglandin – Cryo EM<br />
 +
**[[8bjf]] – hABCC4 + cholesterol – Cryo EM<br />
 +
**[[8bwp]], [[8bwq]], [[8iz7]], [[8j3w]]] – hABCC4 + drug – Cryo EM<br />
 +
**[[8xom]]] – hABCC4 + drug + ANP – Cryo EM<br />
 +
**[[8iza]], [8j3z]] – hABCC4 + ATP – Cryo EM<br />
 +
**[[8bwo]] – hABCC4 (mutant) + ATP – Cryo EM<br />
 +
**[[8xol]] – hABCC8 + ANP – Cryo EM<br />
 +
**[[5ywd]] – hABCC8 + ADP – Cryo EM<br />
**[[7s5v]] – hABCC8 + ADP + ATP – Cryo EM<br />
**[[7s5v]] – hABCC8 + ADP + ATP – Cryo EM<br />
**[[7s5x]], [[7s5y]], [[7s5z]], [[7s60]], [[7s61]], [[7w4o]] – hABCC8 + potassium channel + ADP + ATP – Cryo EM<br />
**[[7s5x]], [[7s5y]], [[7s5z]], [[7s60]], [[7s61]], [[7w4o]] – hABCC8 + potassium channel + ADP + ATP – Cryo EM<br />
-
**[[7rr9]], [[7rra]], [[7vwc]] – hABCD1 – Cryo EM<br />
+
**[[7rr9]], [[7rra]], [[7vwc]], [[7yrq]] – hABCD1 – Cryo EM<br />
**[[7shn]], [[7vzb]] – hABCD1 + CoA derivative – Cryo EM<br />
**[[7shn]], [[7vzb]] – hABCD1 + CoA derivative – Cryo EM<br />
**[[7vx8]], [[7shm]] – hABCD1 + ATP – Cryo EM<br />
**[[7vx8]], [[7shm]] – hABCD1 + ATP – Cryo EM<br />
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**[[7ojh]] – hABCG2 + drug – Cryo EM<br />
**[[7ojh]] – hABCG2 + drug – Cryo EM<br />
**[[7oji]] – hABCG2 + drug + cholesterol – Cryo EM<br />
**[[7oji]] – hABCG2 + drug + cholesterol – Cryo EM<br />
 +
**[[8u2c]] – hABCG2 + antibody – Cryo EM<br />
 +
**[[5njg]] – hABCG2 (mutant) + antibody – Cryo EM<br />
**[[7neq]], [[7nez]], [[7nfd]] – hABCG2 + drug + antibody – Cryo EM<br />
**[[7neq]], [[7nez]], [[7nfd]] – hABCG2 + drug + antibody – Cryo EM<br />
**[[7niu]] – hABCG4 + antibody + cholesterol – Cryo EM<br />
**[[7niu]] – hABCG4 + antibody + cholesterol – Cryo EM<br />
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*Non-human ABC transporters subfamilies
*Non-human ABC transporters subfamilies
-
**[[7oti]] – mABCG1A – Cryo EM<br />
+
**[[7v5d]] – mABCB9 – Cryo EM<br />
-
**[[7otg]] – mABCG1A + drug – Cryo EM<br />
+
**[[7v5c]] – mABCB9 + ADP – Cryo EM<br />
 +
**[[7vfi]] – mABCB9 + peptide – Cryo EM<br />
 +
**[[8woi]] – AtABCB19 – Cryo EM<br />
 +
**[[8wom]] – AtABCB19 + plant hormone – Cryo EM<br />
 +
**[[8woo]] – AtABCB19 + plant hormone + AMP-PNP – Cryo EM<br />
 +
**[[8wp0]] – AtABCB19 (mutant) + ATP – Cryo EM<br />
 +
**[[7n58]] – AtABCB25 – Cryo EM<br />
**[[7vlr]] – rABCC9 + ADP + ATP – Cryo EM<br />
**[[7vlr]] – rABCC9 + ADP + ATP – Cryo EM<br />
**[[7vls]], [[7vlt]], [[7vlu]] – rABCC9 + drug + ADP + ATP – Cryo EM<br />
**[[7vls]], [[7vlt]], [[7vlu]] – rABCC9 + drug + ADP + ATP – Cryo EM<br />
 +
**[[7oti]] – mABCG1A – Cryo EM<br />
 +
**[[7otg]] – mABCG1A + drug – Cryo EM<br />
 +
**]]8i38]], [[8i3c]], [[8i3d]], [[8iwj]], [[8k0z]], [[8wd6]] – AtABCG25 – Cryo EM<br />
 +
**[[8wba]] – AtABCG25 + cholesterol – Cryo EM<br />
 +
**[[8i3a]], [[8i3b]], [[8iwn]], [[8wam]] – AtABCG25 (mutant) + ATP – Cryo EM<br />
 +
**[[8i39]], [[8iwk]], [[8k0x]], [[8wbx]] – AtABCG25 + abscisic acid derivative – Cryo EM<br />
*Lipoprotein-release ABC transporter LolCDE
*Lipoprotein-release ABC transporter LolCDE
Line 419: Line 460:
**[[2pcj]], [[2pcl]] – AaLolD <br />
**[[2pcj]], [[2pcl]] – AaLolD <br />
**[[5udf]] – LolE N-terminal – ''Acinetobacter baumannii<''br />
**[[5udf]] – LolE N-terminal – ''Acinetobacter baumannii<''br />
 +
 +
*Cobalamin ABC transporter
 +
 +
**[[8c7p]] – TdABC – ''Thiobacillus denitrificans''<br />
 +
**[[8ovv]] – TdABC + hydroxycobalamin<br />
* ABC unspecified transporters
* ABC unspecified transporters
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**[[4g68]] – ABC transporter - ''Caldanaerobius''<br />
**[[4g68]] – ABC transporter - ''Caldanaerobius''<br />
**[[4wwh]] – MsABC transporter + galactose <br />
**[[4wwh]] – MsABC transporter + galactose <br />
 +
**[[8bnw]] - PtABC transporter – ''Parageobacillus thermoglucosidasius''<br />
 +
**[[8bf6]] - PtABC transporter + siderophore<br />
-
* Cystic fibrosis transmembrane conductance regulator (CFTR)
+
* Cystic fibrosis transmembrane conductance regulator (CFTR) or hABCC7; Domains – NBD1 387-646; NBD2 – 1202-1430
 +
**[[5uak]] – hCFTR – Cryo EM <br />
 +
**[[8ej1]] – hCFTR (mutant) – Cryo EM <br />
**[[6o2p]], [[6o1v]] – hCFTR + peptide – Cryo EM <br />
**[[6o2p]], [[6o1v]] – hCFTR + peptide – Cryo EM <br />
**[[6msm]] – hCFTR + peptide + cholesterol + ATP – Cryo EM <br />
**[[6msm]] – hCFTR + peptide + cholesterol + ATP – Cryo EM <br />
**[[7svr]] – hCFTR + drug – Cryo EM <br />
**[[7svr]] – hCFTR + drug – Cryo EM <br />
-
**[[7sv7]], [[7svd]] – hCFTR + drug + ATP – Cryo EM <br />
+
**[[8eig]] – hCFTR (mutant) + drug – Cryo EM <br />
-
**[[3gd7]] – hCFTR/malK+N6-phenylethyl-ATP<br />
+
**[[8fzq]] – hCFTR + ATP – Cryo EM <br />
-
**[[2pze]], [[2pzf]], [[2pzg]], [[5uak]] – hCFTR NBD1<br />
+
**[[8v7z]] – hCFTR (mutant) + ATP – Cryo EM <br />
-
**[[2bbo]], [[2bbs]], [[2bbt]] - hCFTR NBD1 (mutant)<br />
+
**[[7sv7]], [[7svd]], [[8eio]], [[8eiq]] – hCFTR + drug + ATP – Cryo EM <br />
-
**[[1xmi]], [[2xmj]], [[1xmj]], [[5tf7]], [[5tf8]], [[5tfa]], [[5tfb]], [[5tfc]], [[5tfd]], [[5tff]], [[5tfg]], [[5tfi]], [[5tfj]], [[4wz6]], [[5tgk]] - hCFTR NBD1 (mutant)+ nucleotide<br />
+
**[[8ubr]], [[8v81]] – hCFTR + inhibitor + ATP – Cryo EM <br />
-
**[[6gkd]], [[6gk4]], [[6gju]], [[6gjs]], [[6gjq]] - hCFTR NBD1 (mutant) + antibody<br />
+
**[[8gls]] – hCFTR + modulator – Cryo EM <br />
 +
**[[3gd7]] – hCFTR/malK+N6-phenylethyl-ATP
 +
**[[2pze]], [[2pzf]], [[2pzg]] – hCFTR NBD1
 +
**[[2bbo]], [[2bbs]], [[2bbt]] - hCFTR NBD1 (mutant)
 +
**[[1xmi]], [[2xmj]], [[1xmj]], [[5tf7]], [[5tf8]], [[5tfa]], [[5tfb]], [[5tfc]], [[5tfd]], [[5tff]], [[5tfg]], [[5tfi]], [[5tfj]], [[4wz6]], [[5tgk]] - hCFTR NBD1 (mutant)+ nucleotide
 +
**[[6gkd]], [[6gk4]], [[6gju]], [[6gjs]], [[6gjq]] - hCFTR NBD1 (mutant) + antibody<br />
**[[6uk1]] - hCFTR NBD2 (mutant) + ATP<br />
**[[6uk1]] - hCFTR NBD2 (mutant) + ATP<br />
-
**[[1xf9]], [[2xfa]], [[1xfa]], [[3si7]] - mCFTR NBD1 (mutant) - mouse<br />
+
**[[1xf9]], [[2xfa]], [[1xfa]], [[3si7]] - mCFTR NBD1 (mutant) - mouse
-
**[[1q3h]] - mCFTR NBD1+AMPPNP<br />
+
**[[1q3h]] - mCFTR NBD1+AMPPNP
-
**[[1r0w]] - mCFTR NBD1<br />
+
**[[1r0w]] - mCFTR NBD1
-
**[[1r0x]], [[1r0z]], [[1r10]] - mCFTR NBD1+ATP<br />
+
**[[1r0x]], [[1r0z]], [[1r10]]- mCFTR NBD1+ATP
-
**[[1r0y]] - mCFTR NBD1+ADP<br />
+
**[[1r0y]] - mCFTR NBD1+ADP
-
**[[1ckw]], [[1ckx]], [[1cky]], [[1ckz]] – CFTR F508 region - NMR<br />
+
**[[6d3r]], [[6d3s]] - CFTR + ATP – chicken <br />
**[[6d3r]], [[6d3s]] - CFTR + ATP – chicken <br />
**[[5uar]] - zCFTR – zebrafish – Cryo EM<br />
**[[5uar]] - zCFTR – zebrafish – Cryo EM<br />
-
**[[5w81]] - zCFTR + ATP – Cryo EM<br /
+
**[[5w81]] - zCFTR + ATP – Cryo EM<br />
 +
 
}}
}}
[[Category: Topic Page]]
[[Category: Topic Page]]

Current revision

3D Structures of ABC transporter

Updated on 03-September-2024

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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