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Adaptin 3D structures

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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
-
*AP-α-2
+
*AP1γ
-
**[[1b9k]], [[1qts]] – mAP appendage domain – mouse<br />
+
**[[1iu1]] – hAP1γ-1 appendage domain 662-785 – human<br />
-
**[[1qtp]] – mAP appendage domain (mutant)<br />
+
**[[4bcx]] – hAP1γ-2 appendage domain<br />
-
**[[1ky6]], [[1kyd]] – mAP appendage domain + epsin peptide<br />
+
**[[2e9g]] – hAP1γ-2 appendage domain - NMR<br />
-
**[[1ky7]] – mAP appendage domain + amphiphysin peptide<br />
+
**[[2ymt]], [[3zhf]] – hAP1γ-2 appendage domain + peptide<br />
-
**[[1kyf]], [[1kyu]] – mAP appendage domain + eps15 peptide<br />
+
**[[2a7b]] – mAP1γ-1 appendage domain – mouse <br />
-
**[[1w80]], [[2vj0]] – mAP appendage domain + synaptojanin peptide<br />
+
**[[1gyw]], [[1gyv]], [[1gyu]] – mAP1γ-1 appendage domain (mutant) <br />
-
**[[3hs8]] – mAP appendage domain + intersectin peptide<br />
+
**[[3zy7]] – mAP1γ-1 appendage domain (mutant) - NMR<br />
-
*AP-β
+
*AP1μ
-
**[[1e42]] – hAP-1 appendage domain - human<br />
+
**[[4emz]], [[4en2]] – mAP1μ-1 sorting motif recognition domain 158-423 + NEF + MHC-I<br />
-
**[[2g30]] – hAP-1 appendage domain + ARH peptide<br />
+
-
**[[3h1z]] – hAP-1 appendage domain + PTDINSPKI-γ peptide<br />
+
-
**[[3hs9]] – hAP-1 appendage domain + intersectin peptide<br />
+
-
**[[2iv9]] – hAP-2 appendage domain + eps15 peptide<br />
+
-
**[[2iv8]] – hAP-2 appendage domain + B-arrestin peptide<br />
+
-
**[[1mj7]] – hAP-4 appendage domain <br />
+
-
*AP-γ
+
*AP1β + AP1γ + AP1μ + AP1σ
-
**[[1iu1]] – hAP-1 ear domain<br />
+
**[[6cm9]], [[6d84]] – hAPβ-1 + AP1γ-1 + AP1μ-1 + AP1σ-3 + NEF + GTP - Cryo EM<br />
-
**[[1gyu]], [[2a7b]] – mAP-1 appendage domain <br />
+
**[[6dff]], [[6cri]] – hAP1β-1 + AP1γ-1 + AP1μ-1 + AP1σ-3 + NEF + ARF1 + GTP - Cryo EM<br />
-
**[[1gyv]], [[1gyw]], [[3zy7]] – mAP-1 appendage domain (mutant)<br />
+
**[[4p6z]] – mAP1β-1 + hAP1-γ-1 + mAP1μ-1 + hAP1σ-1 + VPU + bone marrow stromal antigen peptide<br />
-
**[[2e9g]], [[4bcx]] – hAP-2 ear domain<br />
+
**[[4hmy]] – mAP1β-1 + AP1γ-1 + AP1μ-1 + AP1σ-3 + ARF1 + GTP <br />
-
**[[2ymt]] – hAP-2 ear domain + peptide<br />
+
**[[1w63]] – rAP1β-1 + mAP1γ-1 + mAP1μ-1 + mAP1σ-3 - rat <br />
-
**[[3zhf]] – hAP-2 ear domain + large envelope protein peptide<br />
+
-
*AP-δ-1
+
*AP2α; domain - appendage 702-938
-
**[[4afi]] – hAP-1/vesicle-associated membrane protein 7<br />
+
**[[1b9k]], [[1qts]] – mAP2α appendage domain <br />
 +
**[[1qtp]] – mAPα appendage domain (mutant)<br />
 +
**[[1ky6]], [[1kyd]] – mAP2α appendage domain + epsin peptide<br />
 +
**[[1ky7]] – mAPα appendage domain + amphiphysin peptide<br />
 +
**[[1kyf]], [[1kyu]] – mAP2α appendage domain + eps15 peptide<br />
 +
**[[1w80]], [[2vj0]] – mAP2α2 appendage domain + synaptojanin peptide<br />
 +
**[[3hs8]] – mAP2α appendage domain + intersectin peptide<br />
-
*AP-μ
+
*AP2β
-
**[[3h85]] – rAP-1 appendage domain + PTDINSPKIγ peptide<br />
+
**[[1e42]] – hAP2β1 appendage domain - human<br />
-
**[[4emz]], [[4en2]] – mAP-1 sorting motif recognition domain + nef + MHC-I<br />
+
**[[2g30]] – hAP2β1 appendage domain + ARH peptide<br />
-
**[[2bp5]] – rAP-2 + purinoceptor peptide<br />
+
**[[3h1z]] – hAP2β1 appendage domain + PTDINSPKI-γ peptide<br />
-
**[[1bw8]], [[1i31]] – rAP-2 C-terminal + EGFR peptide<br />
+
**[[3hs9]] – hAP2β1 appendage domain + intersectin peptide<br />
-
**[[1bxx]] – rAP-2 C-terminal + TGN38 peptide<br />
+
**[[2iv9]] – hAP2β2 appendage domain + eps15 peptide<br />
-
**[[1hes]] – rAP-2 C-terminal + selectin peptide<br />
+
**[[2iv8]] – hAP2β2 appendage domain + B-arrestin peptide<br />
-
**[[5c7z]], [[5fpi]] – rAP-2 C terminal + integrin peptide<br />
+
**[[6yai]], [[7om8]] – hAP2β2 + clathrin – Cryo EM<br />
-
**[[2pr9]] – rAP-2 C-terminal + GABA receptor peptide<br />
+
**[[7ohi]], [[7ohz]], [[7oi5]], [[7oiq]] – hAP2β2 + F-BAR<br />
-
**[[5wrm]], [[5wrl]], [[5wrk]] – rAP-2 C-terminal + insulin receptor substrate peptide <br />
+
**[[1mj7]] – hAP2β4 appendage domain <br />
-
**[[4ikn]] – rAP-3 + TGN38 sorting peptide <br />
+
-
**[[3l81]], [[4mdr]] – hAP-4 + amyloid beta-A4 peptide <br />
+
-
**[[6bnt]] – hAP-2 C-terminal + insulin receptor substrate peptide <br />
+
-
*AP-α2 + AP-σ
+
*AP2γ
-
**[[4nee]] – rAP-2 + HIV-1 NEF <br />
+
**[[1iu1]] – hAP2γ1 appendage domain<br />
 +
**[[2e9g]], [[4bcx]] – hAP2γ2 appendage domain<br />
 +
**[[2ymt]] – hAP2γ2 appendage domain + peptide<br />
 +
**[[3zhf]] – hAP2γ2 appendage domain + large envelope protein peptide<br />
 +
**[[1gyu]], [[2a7b]] – mAP2γ1 appendage domain <br />
 +
**[[1gyv]], [[1gyw]], [[3zy7]] – mAP2γ1 appendage domain (mutant)<br />
-
*AP-α2 + AP-β + AP-σ
+
*AP2μ; Domain - C-terminal 158-433
-
**[[4uqi]] – rAP-2 + VPU <br />
+
**[[6bnt]] – hAP2μ2 C-terminal + insulin receptor substrate peptide <br />
 +
**[[7ofp]] – rAP2μ1 C-terminal - rat<br />
 +
**[[4emz]], [[4en2]] – mAP2μ1 C-terminal + NEF + MHC-I<br />
 +
**[[3h85]] – rAP2μ1 C-terminal + PTDINSPKIγ peptide - rat<br />
 +
**[[2bp5]] – rAP2μ2 + purinoceptor peptide<br />
 +
**[[1bw8]], [[1i31]] – rAP2μ2 C-terminal + EGFR peptide<br />
 +
**[[1bxx]] – rAP2μ2 C-terminal + TGN38 peptide<br />
 +
**[[1hes]] – rAP2μ2 C-terminal + selectin peptide<br />
 +
**[[5c7z]], [[5fpi]] – rAP2μ2 C terminal + integrin peptide<br />
 +
**[[2pr9]] – rAP2μ2 C-terminal + GABA receptor peptide<br />
 +
**[[5wrm]], [[5wrl]], [[5wrk]] – rAP2μ2 C-terminal + insulin receptor substrate peptide <br />
-
*AP-α + AP-β + AP-μ + AP-σ
+
*AP2α + AP2σ
-
**[[2vgl]] – rAPα-2 + APβ-1 + APμ-1 + APσ-1 <br />
+
**[[4nee]] – rAP2 + HIV-1 NEF <br />
-
**[[4uqi]] – rAPα-2 + APβ-2 + APμ-2 + APσ-1 <br />
+
-
**[[2jkr]], [[2jkt]] – mAPα-2 + APβ-1 + APμ-1 + APσ-1 + CD4 peptide<br />
+
-
**[[2xa7]] – rAPα-2 + APβ + APμ + APσ + cargo peptide<br />
+
-
*AP-β-1 + AP-γ-1 + AP-μ-1 + AP-σ-3
+
*AP2α2 + AP2β + AP2σ
-
**[[6dff]], [[6d84]], [[6d83]], [[6cri]], [[6cm9]] – hAPβ-1 + APμ-1 + APσ-3 + ARF1 + tetherin-NEF – Cryo EM <br />
+
**[[4uqi]] – rAP2 + VPU <br />
-
*AP-γ + AP-β + AP-μ + AP-σ
+
*AP2α + AP2β + AP2μ + AP2σ
 +
 
 +
**[[2vgl]] – rAP2α2 + AP2β1 + AP2μ1 + AP2σ1 <br />
 +
**[[4uqi]] – rAP2α2 + AP2β2 + AP2μ2 + AP2σ1 <br />
 +
**[[2xa7]] – rAP2α2 + APβ + APμ + APσ + cargo peptide<br />
 +
**[[6qh5]] – rAPα + rAPβ + APμ-1 + APσ<br />
 +
**[[6uri]] – rAPα + hAPβ + hAPμ-1 + hAPσ + NEF <br />
 +
**[[6qh6]], [[6qh7]] – rAPα + rAPβ + APμ-1 + APσ + TGN38 peptide + CD4 peptide<br />
 +
**[[6yah]], [[6yae]] – rAP2α2 + hAPβ + rAPμ + mAPσ – Cryo EM<br />
 +
**[[6yaf]] – rAPα2 + hAPβ + rAPμ + mAPσ + hTGN38 peptide – Cryo EM<br />
 +
**[[2jkr]], [[2jkt]] – mAP2α2 + AP2β1 + AP2μ1 + AP2σ1 + CD4 peptide<br />
 +
**[[6owo]] – mAP2α2 + APβ + APμ + APσ + NECAP – Cryo EM<br />
 +
**[[6oxl]] – mAP2α2 + APβ + APμ + APσ + NECAP + DNA – Cryo EM<br />
 +
**[[7rw8]], [[7rw9]], [[7rwb]] – mAP2α2 + APβ + APμ + APσ – Cryo EM<br />
 +
**[[7rwc]] – mAP2α2 + APβ + APμ + APσ + SGIP – Cryo EM<br />
 +
**[[7rwa]], [[8t1o]] – mAP2α2 + APβ + APμ + APσ + Tgn38 peptide – Cryo EM<br />
 +
**[[7oho]], [[7z5c]] – rAP2α2 + hAPβ + rAPμ + mAPσ<br />
 +
**[[6owt]] – rAP2α2 + rAPβ + mAPμ + rAPσ + tetherin – Cryo EM<br />
 +
 
 +
*AP2β1 + AP2γ1 + AP2μ1 + AP2σ3
 +
 
 +
**[[6dff]], [[6d84]], [[6d83]], [[6cri]], [[6cm9]] – hAP2β1 + AP2μ1 + AP2σ3 + ARF1 + tetherin-NEF – Cryo EM <br />
 +
**[[7ux3]], [[8d4c]], [[8d4d]], [[8d4e]], [[8d4f]], [[8d4g]], [[8d9r]], [[8d9s]], [[8d9t]], [[8d9u]], [[8d9w]] – hAP2β1 + AP2μ1 + AP2σ3 + ARF1 + NEF + MHC-I – Cryo EM <br />
 +
**[[7r4h]] – hAP2β1 + AP2μ1 + AP2σ3 + ARF1 + HSTING – Cryo EM <br />
 +
 
 +
 
 +
*AP2γ1 + AP2β1 + AP2μ1 + AP2σ1
 +
 
 +
**[[1w63]] – mAP2 <br />
 +
**[[4hmy]] – mAP2 + ADP-ribosylation factor<br />
 +
**[[4p6z]] – mAP2 + VPU + bone marrow stromal antigen<br />
 +
 
 +
*AP3μ
 +
 
 +
**[[4ikn]] – rAP3μ1 + TGN38 sorting peptide <br />
 +
 
 +
*AP3δ
 +
 
 +
**[[4afi]] - hAP3δ1/mVAMP7<br />
 +
 
 +
*AP3μ + AP3δ
 +
 
 +
**[[7p3x]], [[7p3y]], [[7p3z]] – yAP3 – yeast - Cryo EM<br />
 +
 
 +
*AP4β
 +
 
 +
**[[2mj7]] - hAP4β appendage domain - NMR<br />
 +
 
 +
*AP4μ
 +
 
 +
**[[3l81]], [[4mdr]] – hAP2μ1 C-terminal + amyloid beta-A4 peptide <br />
-
**[[1w63]] – mAP-1 <br />
 
-
**[[4hmy]] – mAP-1 + ADP-ribosylation factor<br />
 
-
**[[4p6z]] – mAP-1 + VPU + bone marrow stromal antigen<br />
 
}}
}}
[[Category: Topic Page]]
[[Category: Topic Page]]

Current revision

3D structures of Adaptin

Updated on 11-September-2024


Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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