5xj7

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==Crystal structure of PlsY (YgiH), an integral membrane glycerol 3-phosphate acyltransferase - the acyl phosphate form==
==Crystal structure of PlsY (YgiH), an integral membrane glycerol 3-phosphate acyltransferase - the acyl phosphate form==
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<StructureSection load='5xj7' size='340' side='right' caption='[[5xj7]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
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<StructureSection load='5xj7' size='340' side='right'caption='[[5xj7]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5xj7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XJ7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XJ7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5xj7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XJ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XJ7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=78M:(2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78M</scene>, <scene name='pdbligand=87O:phosphono+hexadecanoate'>87O</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.772&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=FME:N-FORMYLMETHIONINE'>FME</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=78M:(2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE'>78M</scene>, <scene name='pdbligand=87O:phosphono+hexadecanoate'>87O</scene>, <scene name='pdbligand=FME:N-FORMYLMETHIONINE'>FME</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5xj5|5xj5]], [[5xj6|5xj6]], [[5xj8|5xj8]], [[5xj9|5xj9]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xj7 OCA], [https://pdbe.org/5xj7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xj7 RCSB], [https://www.ebi.ac.uk/pdbsum/5xj7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xj7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xj7 OCA], [http://pdbe.org/5xj7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xj7 RCSB], [http://www.ebi.ac.uk/pdbsum/5xj7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xj7 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PLSY_AQUAE PLSY_AQUAE]] Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
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[https://www.uniprot.org/uniprot/PLSY_AQUAE PLSY_AQUAE] Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Li, D]]
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[[Category: Aquifex aeolicus VF5]]
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[[Category: Li, Z]]
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[[Category: Large Structures]]
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[[Category: Tang, Y]]
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[[Category: Li D]]
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[[Category: 16:0-p]]
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[[Category: Li Z]]
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[[Category: Acyl phosphate]]
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[[Category: Tang Y]]
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[[Category: Acylp]]
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[[Category: Glycerylphosphate acyltransferase]]
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[[Category: Gpat]]
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[[Category: In meso]]
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[[Category: Lipid cubic phase]]
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[[Category: Lipid metabolism]]
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[[Category: Lipidic cubic phase]]
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[[Category: Monoacylglycerol]]
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[[Category: Palmitoyl phosphate]]
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[[Category: Phospholipid biosynthesis]]
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[[Category: Plsy]]
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[[Category: Substrate]]
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[[Category: Transferase]]
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[[Category: Ygih]]
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Current revision

Crystal structure of PlsY (YgiH), an integral membrane glycerol 3-phosphate acyltransferase - the acyl phosphate form

PDB ID 5xj7

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