Sandbox Button
From Proteopedia
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<text>Orth(A) pH 9.0</text> | <text>Orth(A) pH 9.0</text> | ||
</jmolButton> | </jmolButton> | ||
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<jmolButton> | <jmolButton> | ||
<script>script /scripts/10/1056673/Fig_6b/8.spt | <script>script /scripts/10/1056673/Fig_6b/8.spt | ||
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</jmolButton> | </jmolButton> | ||
</jmol> | </jmol> | ||
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<jmol> | <jmol> | ||
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<text>Orth(A) pH 6.0</text> | <text>Orth(A) pH 6.0</text> | ||
</jmolButton> | </jmolButton> | ||
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<jmolButton> | <jmolButton> | ||
<script>script /scripts/10/1056673/Fig_6d/3.spt | <script>script /scripts/10/1056673/Fig_6d/3.spt | ||
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</jmol> | </jmol> | ||
| + | <jmol> | ||
| + | <jmolButton> | ||
| + | <script>script /scripts/10/1056673/Fig_6e/2.spt | ||
| + | hide water; set zshade off</script> | ||
| + | <text>Mono pH 6.0</text> | ||
| + | </jmolButton> | ||
| + | </jmol> | ||
The novel crystal structures of the Cys59Ser and Cys155Ser mutants help to further define the role of the disulfide bond in stabilizing a ligand-free apo conformation that is disfavoured in both mutants. In fact the <scene name='10/1055499/8ov1_8ov2_8vo3/4'>two mutated structures are remarkably similar to the BIA bound WT structure</scene>. | The novel crystal structures of the Cys59Ser and Cys155Ser mutants help to further define the role of the disulfide bond in stabilizing a ligand-free apo conformation that is disfavoured in both mutants. In fact the <scene name='10/1055499/8ov1_8ov2_8vo3/4'>two mutated structures are remarkably similar to the BIA bound WT structure</scene>. | ||
Current revision
Your Heading Here (maybe something like 'Structure')
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
