2z5z

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{{Seed}}
 
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[[Image:2z5z.png|left|200px]]
 
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==Crystal structure of the complex of buffalo Lactoperoxidase with fluoride ion at 3.5A resolution==
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The line below this paragraph, containing "STRUCTURE_2z5z", creates the "Structure Box" on the page.
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<StructureSection load='2z5z' size='340' side='right'caption='[[2z5z]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2z5z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bubalus_bubalis Bubalus bubalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z5Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z5Z FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OSM:1-(OXIDOSULFANYL)METHANAMINE'>OSM</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
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{{STRUCTURE_2z5z| PDB=2z5z | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z5z OCA], [https://pdbe.org/2z5z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z5z RCSB], [https://www.ebi.ac.uk/pdbsum/2z5z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z5z ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PERL_BUBBU PERL_BUBBU] Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN). May protect the udder from infection and promote growth in newborn calves. Inhibits growth of the following bacterial species: E.coli, K.pneumoniae, P.aeruginosa, S.sonnei, S.saphrophyticus, S.epidermidis, and S.dysenteriae.<ref>PMID:12071645</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z5/2z5z_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z5z ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the complex of buffalo Lactoperoxidase with fluoride ion at 3.5A resolution===
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==See Also==
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*[[Lactoperoxidase|Lactoperoxidase]]
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== References ==
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==About this Structure==
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<references/>
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z5Z OCA].
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__TOC__
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[[Category: Peroxidase]]
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</StructureSection>
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[[Category: Bhushan, A.]]
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[[Category: Bubalus bubalis]]
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[[Category: Jain, R.]]
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[[Category: Large Structures]]
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[[Category: Kaur, P.]]
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[[Category: Bhushan A]]
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[[Category: Sharma, S.]]
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[[Category: Jain R]]
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[[Category: Sheikh, I A.]]
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[[Category: Kaur P]]
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[[Category: Singh, N.]]
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[[Category: Sharma S]]
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[[Category: Singh, T P.]]
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[[Category: Sheikh IA]]
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[[Category: Srinivasan, A.]]
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[[Category: Singh N]]
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[[Category: Buffalo]]
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[[Category: Singh TP]]
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[[Category: Complex]]
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[[Category: Srinivasan A]]
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[[Category: Fluoride]]
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[[Category: Lactoperoxidase]]
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[[Category: Oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 6 10:00:18 2008''
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Current revision

Crystal structure of the complex of buffalo Lactoperoxidase with fluoride ion at 3.5A resolution

PDB ID 2z5z

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