6az3

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{{Large structure}}
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==Cryo-EM structure of of the large subunit of Leishmania ribosome bound to paromomycin==
==Cryo-EM structure of of the large subunit of Leishmania ribosome bound to paromomycin==
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<StructureSection load='6az3' size='340' side='right' caption='[[6az3]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<SX load='6az3' size='340' side='right' viewer='molstar' caption='[[6az3]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6az3]] is a 50 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_donovani Leishmania donovani]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AZ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AZ3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6az3]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_donovani Leishmania donovani]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AZ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AZ3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PAR:PAROMOMYCIN'>PAR</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=OMC:O2-METHYLYCYTIDINE-5-MONOPHOSPHATE'>OMC</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OMC:O2-METHYLYCYTIDINE-5-MONOPHOSPHATE'>OMC</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=PAR:PAROMOMYCIN'>PAR</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6az1|6az1]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6az3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6az3 OCA], [https://pdbe.org/6az3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6az3 RCSB], [https://www.ebi.ac.uk/pdbsum/6az3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6az3 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6az3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6az3 OCA], [http://pdbe.org/6az3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6az3 RCSB], [http://www.ebi.ac.uk/pdbsum/6az3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6az3 ProSAT]</span></td></tr>
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</table>
</table>
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{{Large structure}}
 
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RL37_LEIDO RL37_LEIDO]] Binds to the 23S rRNA.
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[https://www.uniprot.org/uniprot/A0A504XXD2_LEIDO A0A504XXD2_LEIDO]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6az3" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6az3" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ribosome 3D structures|Ribosome 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
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</StructureSection>
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</SX>
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[[Category: Large Structures]]
[[Category: Leishmania donovani]]
[[Category: Leishmania donovani]]
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[[Category: Bashan, A]]
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[[Category: Bashan A]]
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[[Category: Isobe, T]]
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[[Category: Isobe T]]
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[[Category: Jaffe, C L]]
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[[Category: Jaffe CL]]
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[[Category: Matzov, D]]
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[[Category: Matzov D]]
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[[Category: Nobe, Y]]
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[[Category: Nobe Y]]
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[[Category: Rozenberg, H]]
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[[Category: Rozenberg H]]
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[[Category: Shalev-Benami, M]]
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[[Category: Shalev-Benami M]]
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[[Category: Skiniotis, G]]
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[[Category: Skiniotis G]]
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[[Category: Taoka, M]]
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[[Category: Taoka M]]
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[[Category: Yonath, A]]
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[[Category: Yonath A]]
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[[Category: Zhang, Y]]
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[[Category: Zhang Y]]
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[[Category: Zimmerman, E]]
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[[Category: Zimmerman E]]
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[[Category: Aminoglycoside]]
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[[Category: Leishmania]]
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[[Category: Paromomycin]]
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[[Category: Ribosome]]
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[[Category: Ribosome-antibiotic complex]]
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Current revision

Cryo-EM structure of of the large subunit of Leishmania ribosome bound to paromomycin

6az3, resolution 2.50Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

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