7jxk
From Proteopedia
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==EGFR kinase (T790M/V948R) in complex with PF-06747775 and JBJ-04-125-02== | ==EGFR kinase (T790M/V948R) in complex with PF-06747775 and JBJ-04-125-02== | ||
| - | <StructureSection load='7jxk' size='340' side='right'caption='[[7jxk]]' scene=''> | + | <StructureSection load='7jxk' size='340' side='right'caption='[[7jxk]], [[Resolution|resolution]] 3.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JXK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JXK FirstGlance]. <br> | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JXK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JXK FirstGlance]. <br> | ||
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jxk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jxk OCA], [https://pdbe.org/7jxk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jxk RCSB], [https://www.ebi.ac.uk/pdbsum/7jxk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jxk ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8BS:N-[(3R,4R)-4-FLUORO-1-{6-[(3-METHOXY-1-METHYL-1H-PYRAZOL-4-YL)AMINO]-9-METHYL-9H-PURIN-2-YL}PYRROLIDIN-3-YL]PROPANAMIDE'>8BS</scene>, <scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=JBJ:(2R)-2-(5-fluoro-2-hydroxyphenyl)-2-{1-oxo-6-[4-(piperazin-1-yl)phenyl]-1,3-dihydro-2H-isoindol-2-yl}-N-(1,3-thiazol-2-yl)acetamide'>JBJ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jxk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jxk OCA], [https://pdbe.org/7jxk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jxk RCSB], [https://www.ebi.ac.uk/pdbsum/7jxk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jxk ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Epidermal growth factor receptor 3D structures|Epidermal growth factor receptor 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
EGFR kinase (T790M/V948R) in complex with PF-06747775 and JBJ-04-125-02
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