7p5j

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<StructureSection load='7p5j' size='340' side='right'caption='[[7p5j]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
<StructureSection load='7p5j' size='340' side='right'caption='[[7p5j]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7p5j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P5J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P5J FirstGlance]. <br>
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P5J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P5J FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTYH1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p5j OCA], [https://pdbe.org/7p5j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p5j RCSB], [https://www.ebi.ac.uk/pdbsum/7p5j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p5j ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p5j OCA], [https://pdbe.org/7p5j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p5j RCSB], [https://www.ebi.ac.uk/pdbsum/7p5j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p5j ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
 
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[[https://www.uniprot.org/uniprot/TTYH1_HUMAN TTYH1_HUMAN]] Probable chloride channel. May be involved in cell adhesion (By similarity). Isoform 3 may be a Ca(2+)-independent and swelling-activated chloride channel, possibly involved in regulation of cell volume.
 
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__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Deneka, D]]
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[[Category: Deneka D]]
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[[Category: Dutzler, R]]
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[[Category: Dutzler R]]
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[[Category: Sawicka, M]]
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[[Category: Sawicka M]]
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[[Category: Straub, M S]]
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[[Category: Straub SM]]
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[[Category: Sukalskaia, A]]
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[[Category: Sukalskaia A]]
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[[Category: Lipid metabolism]]
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[[Category: Lipid transport]]
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[[Category: Membrane protein]]
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Current revision

Cryo-EM structure of human TTYH1 in GDN

PDB ID 7p5j

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