7yeu
From Proteopedia
(Difference between revisions)
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| - | ==Superfolder green fluorescent protein with phosphine unnatural amino acid | + | ==Superfolder green fluorescent protein with phosphine unnatural amino acid P3BF== |
<StructureSection load='7yeu' size='340' side='right'caption='[[7yeu]], [[Resolution|resolution]] 1.95Å' scene=''> | <StructureSection load='7yeu' size='340' side='right'caption='[[7yeu]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yeu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yeu OCA], [https://pdbe.org/7yeu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yeu RCSB], [https://www.ebi.ac.uk/pdbsum/7yeu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yeu ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yeu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yeu OCA], [https://pdbe.org/7yeu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yeu RCSB], [https://www.ebi.ac.uk/pdbsum/7yeu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yeu ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GFP_AEQVI GFP_AEQVI] Energy-transfer acceptor. Its role is to transduce the blue chemiluminescence of the protein aequorin into green fluorescent light by energy transfer. Fluoresces in vivo upon receiving energy from the Ca(2+)-activated photoprotein aequorin. | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Phosphine ligands are the most important class of ligands for cross-coupling reactions due to their unique electronic and steric properties. However, metalloproteins generally rely on nitrogen, sulfur, or oxygen ligands. Here, we report the genetic incorporation of P3BF, which contains a biocompatible borane-protected phosphine, into proteins. This step is followed by a straightforward one-pot strategy to perform deboronation and palladium coordination in aqueous and aerobic conditions. The genetically encoded phosphine ligand P3BF should significantly expand our ability to design functional metalloproteins. | ||
| + | |||
| + | Genetically Encoded Phosphine Ligand for Metalloprotein Design.,Duan HZ, Hu C, Li YL, Wang SH, Xia Y, Liu X, Wang J, Chen YX J Am Chem Soc. 2022 Dec 21;144(50):22831-22837. doi: 10.1021/jacs.2c09683. Epub , 2022 Nov 23. PMID:36417425<ref>PMID:36417425</ref> | ||
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| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 7yeu" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
Superfolder green fluorescent protein with phosphine unnatural amino acid P3BF
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Categories: Aequorea victoria | Large Structures | Chen YX | Duan HZ | Hu C | Liu XH | Wang JY
