1mbh

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==MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 2==
==MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 2==
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<StructureSection load='1mbh' size='340' side='right'caption='[[1mbh]], [[NMR_Ensembles_of_Models | 50 NMR models]]' scene=''>
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<StructureSection load='1mbh' size='340' side='right'caption='[[1mbh]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1mbh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MBH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MBH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1mbh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MBH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MBH FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 50 models</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1mbg|1mbg]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mbh OCA], [https://pdbe.org/1mbh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mbh RCSB], [https://www.ebi.ac.uk/pdbsum/1mbh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mbh ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mbh OCA], [https://pdbe.org/1mbh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mbh RCSB], [https://www.ebi.ac.uk/pdbsum/1mbh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mbh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MYB_MOUSE MYB_MOUSE]] Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
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[https://www.uniprot.org/uniprot/MYB_MOUSE MYB_MOUSE] Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mb/1mbh_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mb/1mbh_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Aimoto, S]]
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[[Category: Aimoto S]]
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[[Category: Ametani, Y]]
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[[Category: Ametani Y]]
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[[Category: Hirata, Z]]
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[[Category: Hirata Z]]
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[[Category: Hojo, H]]
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[[Category: Hojo H]]
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[[Category: Ishii, S]]
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[[Category: Ishii S]]
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[[Category: Morikawa, S]]
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[[Category: Morikawa S]]
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[[Category: Nakamura, H]]
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[[Category: Nakamura H]]
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[[Category: Nishimura, Y]]
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[[Category: Nishimura Y]]
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[[Category: Ogata, K]]
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[[Category: Ogata K]]
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[[Category: Sarai, A]]
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[[Category: Sarai A]]
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[[Category: Yoshimura, S]]
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[[Category: Yoshimura S]]
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[[Category: Zhang, R]]
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[[Category: Zhang R]]
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[[Category: Dna binding protein]]
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[[Category: Dna-binding protein]]
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[[Category: Protooncogene product]]
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Current revision

MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 2

PDB ID 1mbh

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