1n1f

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==Crystal Structure of Human Interleukin-19==
==Crystal Structure of Human Interleukin-19==
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<StructureSection load='1n1f' size='340' side='right' caption='[[1n1f]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='1n1f' size='340' side='right'caption='[[1n1f]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1n1f]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N1F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1N1F FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1n1f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N1F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N1F FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1n1f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n1f OCA], [http://pdbe.org/1n1f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1n1f RCSB], [http://www.ebi.ac.uk/pdbsum/1n1f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1n1f ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n1f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n1f OCA], [https://pdbe.org/1n1f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n1f RCSB], [https://www.ebi.ac.uk/pdbsum/1n1f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n1f ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IL19_HUMAN IL19_HUMAN]] May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis (By similarity).
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[https://www.uniprot.org/uniprot/IL19_HUMAN IL19_HUMAN] May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n1/1n1f_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n1/1n1f_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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==See Also==
==See Also==
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*[[Interleukin|Interleukin]]
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*[[Interleukin 3D structures|Interleukin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Chang, C]]
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[[Category: Large Structures]]
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[[Category: Fong, S]]
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[[Category: Chang C]]
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[[Category: Kotenko, S]]
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[[Category: Fong S]]
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[[Category: Kozlov, S]]
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[[Category: Kotenko S]]
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[[Category: Magracheva, E]]
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[[Category: Kozlov S]]
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[[Category: Tobin, G]]
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[[Category: Magracheva E]]
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[[Category: Wlodawer, A]]
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[[Category: Tobin G]]
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[[Category: Zdanov, A]]
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[[Category: Wlodawer A]]
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[[Category: Cytokine]]
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[[Category: Zdanov A]]
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[[Category: Four helix bundle]]
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[[Category: Immune system]]
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[[Category: Interleukin]]
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Current revision

Crystal Structure of Human Interleukin-19

PDB ID 1n1f

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