2bc2

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[[Image:2bc2.jpg|left|200px]]<br /><applet load="2bc2" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="2bc2, resolution 1.70&Aring;" />
 
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'''METALLO BETA-LACTAMASE II FROM BACILLUS CEREUS 569/H/9 AT PH 6.0, TRIGONAL CRYSTAL FORM'''<br />
 
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==About this Structure==
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==METALLO BETA-LACTAMASE II FROM BACILLUS CEREUS 569/H/9 AT PH 6.0, TRIGONAL CRYSTAL FORM==
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2BC2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus] with ZN and SO4 as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] Known structural/functional Sites: <scene name='pdbsite=ZNA:Zn Binding Site, Molecule A'>ZNA</scene> and <scene name='pdbsite=ZNB:Zn Binding Site, Molecule B'>ZNB</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BC2 OCA].
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<StructureSection load='2bc2' size='340' side='right'caption='[[2bc2]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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[[Category: Bacillus cereus]]
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== Structural highlights ==
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[[Category: Beta-lactamase]]
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<table><tr><td colspan='2'>[[2bc2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BC2 FirstGlance]. <br>
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[[Category: Single protein]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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[[Category: Fabiane, S.M.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Sutton, B.J.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bc2 OCA], [https://pdbe.org/2bc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bc2 RCSB], [https://www.ebi.ac.uk/pdbsum/2bc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bc2 ProSAT]</span></td></tr>
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[[Category: SO4]]
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</table>
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[[Category: ZN]]
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== Function ==
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[[Category: antibiotic]]
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[https://www.uniprot.org/uniprot/BLA2_BACCE BLA2_BACCE] Can hydrolyze carbapenem compounds.
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[[Category: beta-lactamase]]
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== Evolutionary Conservation ==
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[[Category: hydrolase]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: metalloenzyme]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bc/2bc2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bc2 ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 18:43:55 2007''
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==See Also==
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Bacillus cereus]]
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[[Category: Large Structures]]
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[[Category: Fabiane SM]]
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[[Category: Sutton BJ]]

Current revision

METALLO BETA-LACTAMASE II FROM BACILLUS CEREUS 569/H/9 AT PH 6.0, TRIGONAL CRYSTAL FORM

PDB ID 2bc2

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