2erx
From Proteopedia
(Difference between revisions)
(New page: 200px<br /> <applet load="2erx" size="450" color="white" frame="true" align="right" spinBox="true" caption="2erx, resolution 1.65Å" /> '''Crystal Structure o...) |
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- | [[Image:2erx.gif|left|200px]]<br /> | ||
- | <applet load="2erx" size="450" color="white" frame="true" align="right" spinBox="true" | ||
- | caption="2erx, resolution 1.65Å" /> | ||
- | '''Crystal Structure of DiRas2 in Complex With GDP and Inorganic Phosphate'''<br /> | ||
- | == | + | ==Crystal Structure of DiRas2 in Complex With GDP and Inorganic Phosphate== |
- | + | <StructureSection load='2erx' size='340' side='right'caption='[[2erx]], [[Resolution|resolution]] 1.65Å' scene=''> | |
- | + | == Structural highlights == | |
- | [[ | + | <table><tr><td colspan='2'>[[2erx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ERX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ERX FirstGlance]. <br> |
- | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> |
- | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2erx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2erx OCA], [https://pdbe.org/2erx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2erx RCSB], [https://www.ebi.ac.uk/pdbsum/2erx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2erx ProSAT]</span></td></tr> | |
- | + | </table> | |
- | [ | + | == Function == |
- | [ | + | [https://www.uniprot.org/uniprot/DIRA2_HUMAN DIRA2_HUMAN] Displays low GTPase activity and exist predominantly in the GTP-bound form. |
- | + | == Evolutionary Conservation == | |
- | + | [[Image:Consurf_key_small.gif|200px|right]] | |
- | + | Check<jmol> | |
- | [ | + | <jmolCheckbox> |
- | [ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/er/2erx_consurf.spt"</scriptWhenChecked> |
- | [[ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
- | + | <text>to colour the structure by Evolutionary Conservation</text> | |
- | + | </jmolCheckbox> | |
- | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2erx ConSurf]. | |
- | [ | + | <div style="clear:both"></div> |
- | [[ | + | |
- | [ | + | |
- | + | ||
- | + | ==See Also== | |
+ | *[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]] | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Arrowsmith C]] | ||
+ | [[Category: Ball LJ]] | ||
+ | [[Category: Burgess N]] | ||
+ | [[Category: Doyle D]] | ||
+ | [[Category: Edwards A]] | ||
+ | [[Category: Elkins J]] | ||
+ | [[Category: Fedorov O]] | ||
+ | [[Category: Niesen FE]] | ||
+ | [[Category: Papagrigoriou E]] | ||
+ | [[Category: Salah E]] | ||
+ | [[Category: Sundstrom M]] | ||
+ | [[Category: Weigelt J]] | ||
+ | [[Category: Yang X]] | ||
+ | [[Category: Von Delft F]] |
Current revision
Crystal Structure of DiRas2 in Complex With GDP and Inorganic Phosphate
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Categories: Homo sapiens | Large Structures | Arrowsmith C | Ball LJ | Burgess N | Doyle D | Edwards A | Elkins J | Fedorov O | Niesen FE | Papagrigoriou E | Salah E | Sundstrom M | Weigelt J | Yang X | Von Delft F