2hpv

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[[Image:2hpv.jpg|left|200px]]<br /><applet load="2hpv" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2hpv, resolution 2.00&Aring;" />
 
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'''Crystal structure of FMN-Dependent azoreductase from Enterococcus faecalis'''<br />
 
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==About this Structure==
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==Crystal structure of FMN-Dependent azoreductase from Enterococcus faecalis==
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2HPV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis] with <scene name='pdbligand=FMN:'>FMN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HPV OCA].
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<StructureSection load='2hpv' size='340' side='right'caption='[[2hpv]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2hpv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HPV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HPV FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hpv OCA], [https://pdbe.org/2hpv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hpv RCSB], [https://www.ebi.ac.uk/pdbsum/2hpv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hpv ProSAT], [https://www.topsan.org/Proteins/SECSG/2hpv TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AZOR_ENTFA AZOR_ENTFA] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity. The enzyme can also reduce a wide range of sulfonated azo dyes. The substrate preference order is methyl Red > Orange II > Ponceau BS > Ponceau S > Orange G > Amaranth.[HAMAP-Rule:MF_01216]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hp/2hpv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hpv ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Enterococcus faecalis]]
[[Category: Enterococcus faecalis]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Chen, H.]]
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[[Category: Chen H]]
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[[Category: Chen, L.]]
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[[Category: Chen L]]
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[[Category: Liu, Z J.]]
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[[Category: Liu ZJ]]
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[[Category: Rose, J.]]
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[[Category: Rose J]]
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[[Category: SECSG, Southeast Collaboratory for Structural Genomics.]]
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[[Category: Wang BC]]
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[[Category: Wang, B C.]]
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[[Category: FMN]]
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[[Category: azoreductase]]
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[[Category: enterococcus faecalis]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: secsg]]
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[[Category: southeast collaboratory for structural genomics]]
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[[Category: structural genomics]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:44:24 2008''
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Current revision

Crystal structure of FMN-Dependent azoreductase from Enterococcus faecalis

PDB ID 2hpv

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Proteopedia Page Contributors and Editors (what is this?)

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