2nvm

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[[Image:2nvm.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of fdxN element excision controlling factor XisI (YP_321976.1) from Anabaena Variabilis ATCC 29413 at 2.19 A resolution==
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|PDB= 2nvm |SIZE=350|CAPTION= <scene name='initialview01'>2nvm</scene>, resolution 2.190&Aring;
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<StructureSection load='2nvm' size='340' side='right'caption='[[2nvm]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2nvm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichormus_variabilis_ATCC_29413 Trichormus variabilis ATCC 29413]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NVM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NVM FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.19&#8491;</td></tr>
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|GENE= YP_321976.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1172 Anabaena variabilis])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nvm OCA], [https://pdbe.org/2nvm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nvm RCSB], [https://www.ebi.ac.uk/pdbsum/2nvm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nvm ProSAT], [https://www.topsan.org/Proteins/JCSG/2nvm TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q3MD55_TRIV2 Q3MD55_TRIV2]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nv/2nvm_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2nvm ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Nitrogen fixation is an important process that converts atmospheric gaseous nitrogen, a form plants cannot utilize, into ammonia that can be easily assimilated. Large serine recombinase XisF (fdxN element site-specific recombinase), together with controlling factors XisH and XisI, plays a critical role in the expression of nitrogen fixation genes of certain Anabaena and Nostoc species of cyanobacteria. All three proteins are required to excise the fdxN DNA element from the chromosome in differentiating heterocysts for the expression of nitrogen fixation related genes. We report the first crystal structures of XisH and XisI proteins, both adopting novel protein folds. Based on the analysis of their sequences and structures, we propose that XisH and XisI proteins function as endonucleases and recombination directionality factors (RDFs), respectively. (c) Proteins 2014;. (c) 2014 Wiley Periodicals, Inc.
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'''Crystal structure of fdxN element excision controlling factor XisI (YP_321976.1) from Anabaena Variabilis ATCC 29413 at 2.19 A resolution'''
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Site-specific recombination of nitrogen-fixation genes in cyanobacteria by XisF-XisH-XisI complex: Structures and models.,Hwang WC, Golden JW, Pascual J, Xu D, Cheltsov A, Godzik A Proteins. 2014 Sep 1. doi: 10.1002/prot.24679. PMID:25179344<ref>PMID:25179344</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==About this Structure==
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</div>
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2NVM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Anabaena_variabilis Anabaena variabilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NVM OCA].
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<div class="pdbe-citations 2nvm" style="background-color:#fffaf0;"></div>
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[[Category: Anabaena variabilis]]
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== References ==
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[[Category: Single protein]]
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<references/>
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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__TOC__
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[[Category: fdxn element excision controlling factor xisi]]
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</StructureSection>
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[[Category: jcsg]]
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[[Category: Large Structures]]
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[[Category: joint center for structural genomic]]
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[[Category: Trichormus variabilis ATCC 29413]]
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[[Category: protein structure initiative]]
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[[Category: psi-2]]
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[[Category: structural genomic]]
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[[Category: yp_321976 1]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:51:45 2008''
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Current revision

Crystal structure of fdxN element excision controlling factor XisI (YP_321976.1) from Anabaena Variabilis ATCC 29413 at 2.19 A resolution

PDB ID 2nvm

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