2eek

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(New page: 200px<br /><applet load="2eek" size="350" color="white" frame="true" align="right" spinBox="true" caption="2eek, resolution 1.85&Aring;" /> '''Crystal structure of...)
Current revision (09:05, 6 November 2024) (edit) (undo)
 
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[[Image:2eek.jpg|left|200px]]<br /><applet load="2eek" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2eek, resolution 1.85&Aring;" />
 
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'''Crystal structure of Atlantic cod trypsin complexed with benzamidine'''<br />
 
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==About this Structure==
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==Crystal structure of Atlantic cod trypsin complexed with benzamidine==
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2EEK is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gadus_morhua Gadus morhua] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=BEN:'>BEN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] Known structural/functional Sites: <scene name='pdbsite=AC1:Ca+Binding+Site+For+Residue+A+401'>AC1</scene> and <scene name='pdbsite=AC2:Ben+Binding+Site+For+Residue+A+301'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EEK OCA].
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<StructureSection load='2eek' size='340' side='right'caption='[[2eek]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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[[Category: Gadus morhua]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[2eek]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gadus_morhua Gadus morhua]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EEK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EEK FirstGlance]. <br>
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[[Category: Trypsin]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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[[Category: Iyaguchi, D.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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[[Category: Toyota, E.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eek FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eek OCA], [https://pdbe.org/2eek PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eek RCSB], [https://www.ebi.ac.uk/pdbsum/2eek PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eek ProSAT]</span></td></tr>
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[[Category: BEN]]
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</table>
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[[Category: CA]]
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== Function ==
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[[Category: NA]]
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[https://www.uniprot.org/uniprot/TRY1_GADMO TRY1_GADMO]
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[[Category: benzamidine inhibited]]
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== Evolutionary Conservation ==
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[[Category: hydrolase]]
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ee/2eek_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eek ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:09:17 2008''
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==See Also==
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*[[Trypsin 3D structures|Trypsin 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Gadus morhua]]
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[[Category: Large Structures]]
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[[Category: Iyaguchi D]]
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[[Category: Toyota E]]

Current revision

Crystal structure of Atlantic cod trypsin complexed with benzamidine

PDB ID 2eek

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