2x4i

From Proteopedia

(Difference between revisions)

Current revision

ORF 114a from Sulfolobus islandicus rudivirus 1

Structural highlights

2x4i is a 4 chain structure with sequence from Sulfolobus islandicus rudivirus 1 variant XX. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.2Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Y114_SIRV1

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

The Scottish Structural Proteomics Facility was funded to develop a laboratory scale approach to high throughput structure determination. The effort was successful in that over 40 structures were determined. These structures and the methods harnessed to obtain them are reported here. This report reflects on the value of automation but also on the continued requirement for a high degree of scientific and technical expertise. The efficiency of the process poses challenges to the current paradigm of structural analysis and publication. In the 5 year period we published ten peer-reviewed papers reporting structural data arising from the pipeline. Nevertheless, the number of structures solved exceeded our ability to analyse and publish each new finding. By reporting the experimental details and depositing the structures we hope to maximize the impact of the project by allowing others to follow up the relevant biology.

The Scottish Structural Proteomics Facility: targets, methods and outputs.,Oke M, Carter LG, Johnson KA, Liu H, McMahon SA, Yan X, Kerou M, Weikart ND, Kadi N, Sheikh MA, Schmelz S, Dorward M, Zawadzki M, Cozens C, Falconer H, Powers H, Overton IM, van Niekerk CA, Peng X, Patel P, Garrett RA, Prangishvili D, Botting CH, Coote PJ, Dryden DT, Barton GJ, Schwarz-Linek U, Challis GL, Taylor GL, White MF, Naismith JH J Struct Funct Genomics. 2010 Jun;11(2):167-80. Epub 2010 Apr 24. PMID:20419351^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Oke M, Carter LG, Johnson KA, Liu H, McMahon SA, Yan X, Kerou M, Weikart ND, Kadi N, Sheikh MA, Schmelz S, Dorward M, Zawadzki M, Cozens C, Falconer H, Powers H, Overton IM, van Niekerk CA, Peng X, Patel P, Garrett RA, Prangishvili D, Botting CH, Coote PJ, Dryden DT, Barton GJ, Schwarz-Linek U, Challis GL, Taylor GL, White MF, Naismith JH. The Scottish Structural Proteomics Facility: targets, methods and outputs. J Struct Funct Genomics. 2010 Jun;11(2):167-80. Epub 2010 Apr 24. PMID:20419351 doi:10.1007/s10969-010-9090-y

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2x4i"

@@ Line 3: / Line 3: @@
 <StructureSection load='2x4i' size='340' side='right'caption='[[2x4i]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2x4i]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_islandicus_rudivirus_1_variant_xx Sulfolobus islandicus rudivirus 1 variant xx]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X4I OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2X4I FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2x4i]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfolobus_islandicus_rudivirus_1_variant_XX Sulfolobus islandicus rudivirus 1 variant XX]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X4I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X4I FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2x4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x4i OCA], [http://pdbe.org/2x4i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x4i RCSB], [http://www.ebi.ac.uk/pdbsum/2x4i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x4i ProSAT]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x4i OCA], [https://pdbe.org/2x4i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x4i RCSB], [https://www.ebi.ac.uk/pdbsum/2x4i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x4i ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/Y114_SIRV1 Y114_SIRV1]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 11: / Line 14: @@
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x4/2x4i_consurf.spt"</scriptWhenChecked>
-    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
@@ Line 30: / Line 33: @@
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Sulfolobus islandicus rudivirus 1 variant xx]]
+[[Category: Sulfolobus islandicus rudivirus 1 variant XX]]
-[[Category: Carter, L G]]
+[[Category: Carter LG]]
-[[Category: Johnson, K A]]
+[[Category: Johnson KA]]
-[[Category: Liu, H]]
+[[Category: Liu H]]
-[[Category: Mcmahon, S A]]
+[[Category: Mcmahon SA]]
-[[Category: Naismith, J H]]
+[[Category: Naismith JH]]
-[[Category: Oke, M]]
+[[Category: Oke M]]
-[[Category: White, M F]]
+[[Category: White MF]]
-[[Category: Archeal virus]]
-[[Category: Duf1874]]
-[[Category: Unknown function]]

2x4i

From Proteopedia

Current revision

ORF 114a from Sulfolobus islandicus rudivirus 1

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

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