1xyy
From Proteopedia
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| - | [[Image:1xyy.jpg|left|200px]]<br /><applet load="1xyy" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1xyy, resolution 1.70Å" /> | ||
| - | '''Low Temperature (100K) Crystal Structure Of Flavodoxin Mutant S64C, homodimer, oxidised state'''<br /> | ||
| - | == | + | ==Low Temperature (100K) Crystal Structure Of Flavodoxin Mutant S64C, homodimer, oxidised state== |
| - | + | <StructureSection load='1xyy' size='340' side='right'caption='[[1xyy]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1xyy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfovibrio_vulgaris Desulfovibrio vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XYY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XYY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr> | |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xyy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xyy OCA], [https://pdbe.org/1xyy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xyy RCSB], [https://www.ebi.ac.uk/pdbsum/1xyy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xyy ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/FLAV_NITV2 FLAV_NITV2] Low-potential electron donor to a number of redox enzymes. | |
| - | [ | + | == Evolutionary Conservation == |
| - | [[ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [ | + | Check<jmol> |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xy/1xyy_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | |
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xyy ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The mutant S64C of the short-chain flavodoxin from Desulfovibrio vulgaris has been designed to introduce an accessible and reactive group on the protein surface. Crystals have been obtained of both the monomeric and homodimeric forms of the protein, with the cofactor FMN in either the oxidized or the one electron-reduced (semiquinone) state, and the structures have been determined to high resolution. The redox properties of the different species have been investigated and the variations observed with respect to wild type have been related to the structural changes induced by the mutation and S-S bridge formation. | ||
| - | + | Redox properties and crystal structures of a Desulfovibrio vulgaris flavodoxin mutant in the monomeric and homodimeric forms.,Fantuzzi A, Artali R, Bombieri G, Marchini N, Meneghetti F, Gilardi G, Sadeghi SJ, Cavazzini D, Rossi GL Biochim Biophys Acta. 2009 Mar;1794(3):496-505. Epub 2008 Dec 11. PMID:19118653<ref>PMID:19118653</ref> | |
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 1xyy" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Flavodoxin 3D structures|Flavodoxin 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Desulfovibrio vulgaris]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Artali R]] | ||
| + | [[Category: Bombieri G]] | ||
| + | [[Category: Cavazzini D]] | ||
| + | [[Category: Gilardi G]] | ||
| + | [[Category: Marchini N]] | ||
| + | [[Category: Meneghetti F]] | ||
| + | [[Category: Rossi GL]] | ||
Current revision
Low Temperature (100K) Crystal Structure Of Flavodoxin Mutant S64C, homodimer, oxidised state
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