2k73

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==Solution NMR structure of integral membrane protein DsbB==
==Solution NMR structure of integral membrane protein DsbB==
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<StructureSection load='2k73' size='340' side='right' caption='[[2k73]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2k73' size='340' side='right'caption='[[2k73]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2k73]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K73 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K73 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2k73]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K73 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K73 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2hi7|2hi7]], [[2k74|2k74]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dsbB, roxB, ycgA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k73 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k73 OCA], [https://pdbe.org/2k73 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k73 RCSB], [https://www.ebi.ac.uk/pdbsum/2k73 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k73 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k73 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k73 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k73 RCSB], [http://www.ebi.ac.uk/pdbsum/2k73 PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DSBB_ECOLI DSBB_ECOLI]] Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by oxidizing the DsbA protein.<ref>PMID:8430071</ref> <ref>PMID:7688471</ref>
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[https://www.uniprot.org/uniprot/DSBB_ECOLI DSBB_ECOLI] Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by oxidizing the DsbA protein.<ref>PMID:8430071</ref> <ref>PMID:7688471</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k7/2k73_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k7/2k73_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k73 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2k73" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Protein disulfide oxidoreductase|Protein disulfide oxidoreductase]]
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*[[Thiol:disulfide interchange protein 3D structures|Thiol:disulfide interchange protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Beckwith, J]]
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[[Category: Large Structures]]
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[[Category: Bushweller, J H]]
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[[Category: Beckwith J]]
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[[Category: Cafiso, D S]]
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[[Category: Bushweller JH]]
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[[Category: Cierpicki, T]]
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[[Category: Cafiso DS]]
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[[Category: Ellena, J F]]
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[[Category: Cierpicki T]]
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[[Category: Jimenez, R H.Flores]]
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[[Category: Ellena JF]]
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[[Category: Kadokura, H]]
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[[Category: Flores Jimenez RH]]
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[[Category: Lukasik, S M]]
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[[Category: Kadokura H]]
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[[Category: Zhou, Y]]
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[[Category: Lukasik SM]]
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[[Category: Chaperone]]
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[[Category: Zhou Y]]
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[[Category: Disulfide bond]]
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[[Category: Dsbb]]
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[[Category: Electron transport]]
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[[Category: Inner membrane]]
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[[Category: Membrane protein]]
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[[Category: Oxidoreductase]]
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[[Category: Redox enzyme]]
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[[Category: Redox-active center]]
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[[Category: Transmembrane]]
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[[Category: Transport]]
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Current revision

Solution NMR structure of integral membrane protein DsbB

PDB ID 2k73

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