2okf

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[[Image:2okf.gif|left|200px]]
 
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{{Structure
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==CRYSTAL STRUCTURE OF A FDXN ELEMENT EXCISION CONTROLLING FACTOR PROTEIN (AVA_3312) FROM ANABAENA VARIABILIS AT 1.60 A RESOLUTION==
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|PDB= 2okf |SIZE=350|CAPTION= <scene name='initialview01'>2okf</scene>, resolution 1.600&Aring;
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<StructureSection load='2okf' size='340' side='right'caption='[[2okf]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
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<table><tr><td colspan='2'>[[2okf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichormus_variabilis Trichormus variabilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OKF FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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|GENE= YP_323815.1, Ava_3312 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1172 Anabaena variabilis])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam08814 XisH]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2okf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2okf OCA], [https://pdbe.org/2okf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2okf RCSB], [https://www.ebi.ac.uk/pdbsum/2okf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2okf ProSAT], [https://www.topsan.org/Proteins/JCSG/2okf TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2okf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2okf OCA], [http://www.ebi.ac.uk/pdbsum/2okf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2okf RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/Q3M7W6_TRIV2 Q3M7W6_TRIV2]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Nitrogen fixation is an important process that converts atmospheric gaseous nitrogen, a form plants cannot utilize, into ammonia that can be easily assimilated. Large serine recombinase XisF (fdxN element site-specific recombinase), together with controlling factors XisH and XisI, plays a critical role in the expression of nitrogen fixation genes of certain Anabaena and Nostoc species of cyanobacteria. All three proteins are required to excise the fdxN DNA element from the chromosome in differentiating heterocysts for the expression of nitrogen fixation related genes. We report the first crystal structures of XisH and XisI proteins, both adopting novel protein folds. Based on the analysis of their sequences and structures, we propose that XisH and XisI proteins function as endonucleases and recombination directionality factors (RDFs), respectively. (c) Proteins 2014;. (c) 2014 Wiley Periodicals, Inc.
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'''Crystal structure of fdxN element excision controlling factor protein (YP_323815.1) from Anabaena variabilis ATCC 29413 at 1.60 A resolution'''
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Site-specific recombination of nitrogen-fixation genes in cyanobacteria by XisF-XisH-XisI complex: Structures and models.,Hwang WC, Golden JW, Pascual J, Xu D, Cheltsov A, Godzik A Proteins. 2014 Sep 1. doi: 10.1002/prot.24679. PMID:25179344<ref>PMID:25179344</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==About this Structure==
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</div>
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2OKF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Anabaena_variabilis Anabaena variabilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OKF OCA].
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<div class="pdbe-citations 2okf" style="background-color:#fffaf0;"></div>
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[[Category: Anabaena variabilis]]
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== References ==
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[[Category: Single protein]]
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<references/>
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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__TOC__
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[[Category: fdxn element excision controlling factor protein]]
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</StructureSection>
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[[Category: jcsg]]
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[[Category: Large Structures]]
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[[Category: joint center for structural genomic]]
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[[Category: Trichormus variabilis]]
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[[Category: protein structure initiative]]
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[[Category: psi-2]]
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[[Category: structural genomic]]
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[[Category: xish protein]]
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[[Category: yp_323815 1]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:19:06 2008''
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Current revision

CRYSTAL STRUCTURE OF A FDXN ELEMENT EXCISION CONTROLLING FACTOR PROTEIN (AVA_3312) FROM ANABAENA VARIABILIS AT 1.60 A RESOLUTION

PDB ID 2okf

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