2pmd

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==The structures of aIF2gamma subunit from the archaeon Sulfolobus solfataricus in the GDP-bound form.==
==The structures of aIF2gamma subunit from the archaeon Sulfolobus solfataricus in the GDP-bound form.==
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<StructureSection load='2pmd' size='340' side='right' caption='[[2pmd]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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<StructureSection load='2pmd' size='340' side='right'caption='[[2pmd]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2pmd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PMD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PMD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2pmd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PMD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PMD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2aho|2aho]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">eif2g ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pmd OCA], [https://pdbe.org/2pmd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pmd RCSB], [https://www.ebi.ac.uk/pdbsum/2pmd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pmd ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pmd OCA], [http://pdbe.org/2pmd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pmd RCSB], [http://www.ebi.ac.uk/pdbsum/2pmd PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IF2G_SULSO IF2G_SULSO]] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity).
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[https://www.uniprot.org/uniprot/IF2G_SACS2 IF2G_SACS2] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.[HAMAP-Rule:MF_00119]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pm/2pmd_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pm/2pmd_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 35091]]
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[[Category: Large Structures]]
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[[Category: Blaesi, U]]
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[[Category: Saccharolobus solfataricus]]
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[[Category: Fedorov, R V]]
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[[Category: Blaesi U]]
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[[Category: Garber, M B]]
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[[Category: Fedorov RV]]
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[[Category: Hasenohrl, D]]
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[[Category: Garber MB]]
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[[Category: Manstein, D J]]
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[[Category: Hasenohrl D]]
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[[Category: Nikonov, O S]]
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[[Category: Manstein DJ]]
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[[Category: Nikonov, S V]]
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[[Category: Nikonov OS]]
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[[Category: Nikulin, A D]]
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[[Category: Nikonov SV]]
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[[Category: Stolboushkina, E A]]
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[[Category: Nikulin AD]]
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[[Category: Aif2]]
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[[Category: Stolboushkina EA]]
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[[Category: Gdp]]
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[[Category: Gdpnp]]
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[[Category: Initiation factor 2 gamma subunit]]
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[[Category: Initiation of the translation]]
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[[Category: Nucleotide binding]]
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[[Category: Pyrophosphate]]
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[[Category: Translation]]
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Current revision

The structures of aIF2gamma subunit from the archaeon Sulfolobus solfataricus in the GDP-bound form.

PDB ID 2pmd

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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