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- | [[Image:3rmr.png|left|200px]] | |
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- | <!-- | + | ==Crystal structure of Hyaloperonospora arabidopsidis ATR1 effector domain== |
- | The line below this paragraph, containing "STRUCTURE_3rmr", creates the "Structure Box" on the page.
| + | <StructureSection load='3rmr' size='340' side='right'caption='[[3rmr]], [[Resolution|resolution]] 2.30Å' scene=''> |
- | You may change the PDB parameter (which sets the PDB file loaded into the applet)
| + | == Structural highlights == |
- | or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
| + | <table><tr><td colspan='2'>[[3rmr]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Hyaloperonospora_parasitica Hyaloperonospora parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RMR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RMR FirstGlance]. <br> |
- | or leave the SCENE parameter empty for the default display.
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
- | --> | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
- | {{STRUCTURE_3rmr| PDB=3rmr | SCENE= }}
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rmr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rmr OCA], [https://pdbe.org/3rmr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rmr RCSB], [https://www.ebi.ac.uk/pdbsum/3rmr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rmr ProSAT]</span></td></tr> |
| + | </table> |
| + | == Function == |
| + | [https://www.uniprot.org/uniprot/ATR1_HYAAE ATR1_HYAAE] Secreted effector that acts as an elicitor of hypersensitive response (HR) specifically on plants carrying both defense protein RPP1 from several ecotypes including RPP1-NdA, RPP1-WsB, RPP1-EstA and RPP1-ZdrA.<ref>PMID:15894715</ref> <ref>PMID:22194907</ref> <ref>PMID:25671309</ref> <ref>PMID:26725254</ref> <ref>PMID:27427964</ref> <ref>PMID:29794019</ref> |
| | | |
- | ===Crystal structure of Hyaloperonospora arabidopsidis ATR1 effector domain=== | + | ==See Also== |
- | | + | *[[Avirulence protein 3D structures|Avirulence protein 3D structures]] |
- | | + | == References == |
- | ==About this Structure== | + | <references/> |
- | [[3rmr]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Hyaloperonospora_parasitica Hyaloperonospora parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RMR OCA].
| + | __TOC__ |
| + | </StructureSection> |
| [[Category: Hyaloperonospora parasitica]] | | [[Category: Hyaloperonospora parasitica]] |
- | [[Category: Alber, T.]] | + | [[Category: Large Structures]] |
- | [[Category: Chou, S.]] | + | [[Category: Alber T]] |
- | [[Category: Holton, J M.]] | + | [[Category: Chou S]] |
- | [[Category: Krasileva, K V.]] | + | [[Category: Holton JM]] |
- | [[Category: Staskawicz, B J.]] | + | [[Category: Krasileva KV]] |
- | [[Category: Alpha-helical]]
| + | [[Category: Staskawicz BJ]] |
- | [[Category: Effector]]
| + | |
- | [[Category: Protein binding]]
| + | |
- | [[Category: R-protein]]
| + | |
- | [[Category: Rpp1]]
| + | |
- | [[Category: Rpp1-recognized]]
| + | |
- | [[Category: Seahorse]]
| + | |
- | [[Category: Virulence]]
| + | |
- | [[Category: W-motif]]
| + | |
| Structural highlights
Function
ATR1_HYAAE Secreted effector that acts as an elicitor of hypersensitive response (HR) specifically on plants carrying both defense protein RPP1 from several ecotypes including RPP1-NdA, RPP1-WsB, RPP1-EstA and RPP1-ZdrA.[1] [2] [3] [4] [5] [6]
See Also
References
- ↑ Rehmany AP, Gordon A, Rose LE, Allen RL, Armstrong MR, Whisson SC, Kamoun S, Tyler BM, Birch PR, Beynon JL. Differential recognition of highly divergent downy mildew avirulence gene alleles by RPP1 resistance genes from two Arabidopsis lines. Plant Cell. 2005 Jun;17(6):1839-50. PMID:15894715 doi:10.1105/tpc.105.031807
- ↑ Krasileva KV, Zheng C, Leonelli L, Goritschnig S, Dahlbeck D, Staskawicz BJ. Global analysis of Arabidopsis/downy mildew interactions reveals prevalence of incomplete resistance and rapid evolution of pathogen recognition. PLoS One. 2011;6(12):e28765. doi: 10.1371/journal.pone.0028765. Epub 2011 Dec 14. PMID:22194907 doi:http://dx.doi.org/10.1371/journal.pone.0028765
- ↑ Steinbrenner AD, Goritschnig S, Staskawicz BJ. Recognition and activation domains contribute to allele-specific responses of an Arabidopsis NLR receptor to an oomycete effector protein. PLoS Pathog. 2015 Feb 11;11(2):e1004665. PMID:25671309 doi:10.1371/journal.ppat.1004665
- ↑ Goritschnig S, Steinbrenner AD, Grunwald DJ, Staskawicz BJ. Structurally distinct Arabidopsis thaliana NLR immune receptors recognize tandem WY domains of an oomycete effector. New Phytol. 2016 May;210(3):984-96. PMID:26725254 doi:10.1111/nph.13823
- ↑ Schreiber KJ, Bentham A, Williams SJ, Kobe B, Staskawicz BJ. Multiple Domain Associations within the Arabidopsis Immune Receptor RPP1 Regulate the Activation of Programmed Cell Death. PLoS Pathog. 2016 Jul 18;12(7):e1005769. PMID:27427964 doi:10.1371/journal.ppat.1005769
- ↑ Atanasov KE, Liu C, Erban A, Kopka J, Parker JE, Alcázar R. NLR Mutations Suppressing Immune Hybrid Incompatibility and Their Effects on Disease Resistance. Plant Physiol. 2018 Jul;177(3):1152-1169. PMID:29794019 doi:10.1104/pp.18.00462
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