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1ugl
From Proteopedia
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[[Image:1ugl.jpg|left|200px]] | [[Image:1ugl.jpg|left|200px]] | ||
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'''Solution structure of S8-SP11''' | '''Solution structure of S8-SP11''' | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1UGL is a [[Single protein]] structure | + | 1UGL is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UGL OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Shirakawa, M.]] | [[Category: Shirakawa, M.]] | ||
[[Category: Takayama, S.]] | [[Category: Takayama, S.]] | ||
| - | [[Category: | + | [[Category: Cysteine-rich]] |
| - | [[Category: | + | [[Category: Defensin-like]] |
| - | [[Category: | + | [[Category: Male determinant of self-incompatibility]] |
| - | [[Category: | + | [[Category: Nmr]] |
| - | [[Category: | + | [[Category: Riken structural genomics/proteomics initiative]] |
| - | [[Category: | + | [[Category: Rsgi]] |
| - | [[Category: | + | [[Category: Scr]] |
| - | [[Category: | + | [[Category: Sp11]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 11:12:00 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 08:12, 3 May 2008
Solution structure of S8-SP11
Overview
Many flowering plants possess a self-incompatibility system to prevent inbreeding. In Brassica rapa, self/non-self recognition in mating is established through S-haplotype-specific interactions between stigma receptors and S-locus protein 11 (SP11, also called S-locus cysteine-rich protein) that is encoded at the highly polymorphic S-locus. Here we describe the solution structure of the SP11 protein of the S8-haplotype (S8-SP11), which specifically binds to the stigma factor of the same haplotype. It folds into an alpha/beta sandwich structure that resembles those of plant defensins. Residues important for structural integrity are highly conserved among the allelic SP11s, suggesting the existence of a common folding pattern. Structure-based sequence alignment and homology modeling of allelic SP11 identified a hyper-variable (HV) region, which is thought to form a loop that bulges out from the body of the protein that is amenable to solvent exposure. We suggest that the HV region could serve as a specific binding site for the stigma receptor.
About this Structure
1UGL is a Single protein structure. Full crystallographic information is available from OCA.
Reference
Structure of the male determinant factor for Brassica self-incompatibility., Mishima M, Takayama S, Sasaki K, Jee JG, Kojima C, Isogai A, Shirakawa M, J Biol Chem. 2003 Sep 19;278(38):36389-95. Epub 2003 Jun 30. PMID:12835321 Page seeded by OCA on Sat May 3 11:12:00 2008
Categories: Single protein | Isogai, A. | Jee, J G. | Kojima, C. | Mishima, M. | RSGI, RIKEN Structural Genomics/Proteomics Initiative. | Sasaki, K. | Shirakawa, M. | Takayama, S. | Cysteine-rich | Defensin-like | Male determinant of self-incompatibility | Nmr | Riken structural genomics/proteomics initiative | Rsgi | Scr | Sp11 | Structural genomic
