Calmodulin 3D structures

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Line 6: Line 6:
* Native CaM
* Native CaM
-
**[[1y6w]], [[1cll]], [[4bw8]] - hCaM - human<br />
+
**[[1y6w]], [[1cll]], [[4bw8]], [[7t2q]] - hCaM - human<br />
**[[2k61]], [[2k0e]] – hCaM – NMR<br />
**[[2k61]], [[2k0e]] – hCaM – NMR<br />
**[[1prw]], [[1deg]] – bCaM - bovine<br />
**[[1prw]], [[1deg]] – bCaM - bovine<br />
**[[4hex]] – mCaM – mouse<br />
**[[4hex]] – mCaM – mouse<br />
-
**[[3cln]] – rCaM - rat<br />
+
**[[1qx5]], [[3cln]] – rCaM - rat<br />
**[[1up5]] – cCaM – chicken<br />
**[[1up5]] – cCaM – chicken<br />
-
**[[1x02]], [[1dmo]] – XlCaM – NMR - ''Xenopus laevis''<br />
+
**[[1cfc]], [[1cfd]], [[1x02]], [[1dmo]] – XlCaM - ''Xenopus laevis'' - NMR
**[[4cln]] – DmCaM - ''Drosophila melanogaster''<br />
**[[4cln]] – DmCaM - ''Drosophila melanogaster''<br />
**[[1ooj]] – CaM – ''Caenorhabditis elegans''<br />
**[[1ooj]] – CaM – ''Caenorhabditis elegans''<br />
**[[1rfj]] – CaM – potato<br />
**[[1rfj]] – CaM – potato<br />
**[[5a2h]] – AtCaM-7 – ''Arabidopsis thaliana''<br />
**[[5a2h]] – AtCaM-7 – ''Arabidopsis thaliana''<br />
 +
**[[1lkj]] – yCaM – yeast - NMR
**[[2lhh]] – yCaM + Ca - yeast - NMR<br />
**[[2lhh]] – yCaM + Ca - yeast - NMR<br />
**[[1clm]], [[1osa]], [[1exr]], [[5e1p]], [[5e1n]], [[5e1k]] – PtCaM - ''Paramecium tetraurelia''<br />
**[[1clm]], [[1osa]], [[1exr]], [[5e1p]], [[5e1n]], [[5e1k]] – PtCaM - ''Paramecium tetraurelia''<br />
Line 23: Line 24:
**[[6dah]] – hCaM (mutant)<br />
**[[6dah]] – hCaM (mutant)<br />
-
**[[2k0j]], [[1sw8]], [[5ggm]], [[5tp5]], [[6gdk]] – hCaM (mutant) – NMR<br />
+
**[[2k0j]], [[1sw8]], [[5ggm]], [[5tp5]], [[6gdk]], [[6gdl]], [[6y94]], [[6y95]], [[8bd2]], [[8bfg]] – hCaM (mutant) – NMR<br />
**[[1ahr]], [[2m3s]] – cCaM (mutant)<br />
**[[1ahr]], [[2m3s]] – cCaM (mutant)<br />
- 
-
* apo CaM
 
- 
-
**[[1qx5]] – rapoCaM – rat<br />
 
-
**[[1cfc]], [[1cfd]] - XlCaM – NMR<br />
 
-
**[[1lkj]] – yCaM – NMR<br />
 
* CaM N-terminal
* CaM N-terminal
Line 45: Line 40:
**[[2hf5]] - hCaM EF2 EF3 – NMR<br />
**[[2hf5]] - hCaM EF2 EF3 – NMR<br />
**[[2lqp]] - hCaM EF3 EF4 – NMR<br />
**[[2lqp]] - hCaM EF3 EF4 – NMR<br />
-
**[1cmf]], [[1cmg]] – bCaM C-terminal – NMR<br />
+
**[[1cmf]], [[1cmg]] – bCaM C-terminal – NMR<br />
**[[1fw4]] - bCaM C-terminal<br />
**[[1fw4]] - bCaM C-terminal<br />
**[[4rjd]] – rCaM<br />
**[[4rjd]] – rCaM<br />
Line 71: Line 66:
**[[1ctr]] - hCaM+trifluoperazine <br />
**[[1ctr]] - hCaM+trifluoperazine <br />
**[[2kug]], [[2kuh]] - hCaM N-terminal EF1 EF2+halothane – NMR<br />
**[[2kug]], [[2kuh]] - hCaM N-terminal EF1 EF2+halothane – NMR<br />
 +
**[[6m7h]] – hCaM + sulfonamide derivative <br />
 +
**[[6os4]] – hCaM-1 + farnesyl derivative <br />
 +
**[[7psz]], [[7pu9]] – hCaM-1 + imidazole derivative <br />
 +
**[[9jqi]] – hCaM-1 + sulfonamide derivative <br />
**[[3if7]] – bCaM+sphingosylphosphorylcholine<br />
**[[3if7]] – bCaM+sphingosylphosphorylcholine<br />
**[[1qiv]], [[1qiw]] – bCaM+DPDv<br />
**[[1qiv]], [[1qiw]] – bCaM+DPDv<br />
Line 86: Line 85:
**[[2l7l]] - hCaM+ CaM-dependent protein kinase 1 CBD<br />
**[[2l7l]] - hCaM+ CaM-dependent protein kinase 1 CBD<br />
**[[6hcs]] - hCaM+ CaM-dependent protein kinase 2 peptide<br />
**[[6hcs]] - hCaM+ CaM-dependent protein kinase 2 peptide<br />
 +
**[[7zrq]] – hCaM (mutant) + CaM-dependent protein kinase 2 peptide<br />
**[[2m0j]], [[2m0k]] - hCaM+olfactory channel peptide<br />
**[[2m0j]], [[2m0k]] - hCaM+olfactory channel peptide<br />
**[[2kne]] – hCaM+PMCA C-terminal CBD<br />
**[[2kne]] – hCaM+PMCA C-terminal CBD<br />
**[[4upu]] - hCaM+ IP3 3-K CBD<br />
**[[4upu]] - hCaM+ IP3 3-K CBD<br />
 +
**[[6y4p]] – hCaM-1+ ryanodine receptor CBD<br />
 +
**[[6jv2]] – hCaM-1+ ryanodine receptor CBD – Cryo EM<br />
 +
**[[6ji8]], [[6jiu]], [[6jrs]], [[6x32]], [[6x33]], [[6x35]], [[6x36]] – hCaM-1+ ryanodine receptor CBD + FKBP1B – Cryo EM<br />
 +
**[[6xxf]], [[6y4o]], [[7kl5]] – hCaM-2+ ryanodine receptor CBD<br />
 +
**[[8k9z]], [[8ka0]], [[8ka1]], [[8ka2]] – hCaM-2+ RID-dependent transforming NADase CBD<br />
**[[3ewt]], [[3ewv]] – hCaM+TNFR fragment<br />
**[[3ewt]], [[3ewv]] – hCaM+TNFR fragment<br />
**[[2w73]], [[2jzi]], [[2r28]] – hCaM+Ser/Thr phosphatase CBD<br />
**[[2w73]], [[2jzi]], [[2r28]] – hCaM+Ser/Thr phosphatase CBD<br />
**[[3bya]] – hCaM+glutamate receptor peptide<br />
**[[3bya]] – hCaM+glutamate receptor peptide<br />
**[[3g43]], [[2vay]], [[2f3y]], [[2f3z]], [[2be6]], [[2lqc]], [[3oxq]] – hCaM+calcium channel CAV1.2<br />
**[[3g43]], [[2vay]], [[2f3y]], [[2f3z]], [[2be6]], [[2lqc]], [[3oxq]] – hCaM+calcium channel CAV1.2<br />
 +
**[[7l8v]] - hCaM+calcium channel CAV1.2 peptide – NMR<br />
**[[3dve]], [[3dvj]], [[3dvk]], [[3dvm]] - hCaM+calcium channel CAV2.2<br />
**[[3dve]], [[3dvj]], [[3dvk]], [[3dvm]] - hCaM+calcium channel CAV2.2<br />
**[[5jth]], [[5jqa]] – hCaM + myosin light chain kinase peptide<br />
**[[5jth]], [[5jqa]] – hCaM + myosin light chain kinase peptide<br />
Line 103: Line 109:
**[[2m55]] – hCaM + α-synuclein peptide<br />
**[[2m55]] – hCaM + α-synuclein peptide<br />
**[[5nin]] – hCaM + A-kinase anchor peptide<br />
**[[5nin]] – hCaM + A-kinase anchor peptide<br />
 +
**[[7bf1]], [[7bf2]] – hCaM + A-kinase anchor peptide<br />
 +
**[[7shq]] – hCaM-1 + creatine kinase peptide - NMR <br />
**[[5j8h]] - hCaM + elongation factor 2 kinase CBD – NMR<br />
**[[5j8h]] - hCaM + elongation factor 2 kinase CBD – NMR<br />
**[[5dow]] - hCaM + chloride anion exchanger CBD <br />
**[[5dow]] - hCaM + chloride anion exchanger CBD <br />
 +
**[[6zbi]] – hCaM-1 + sodium/hydrogen anion exchanger CBD - NMR<br />
 +
**[[6sz5]] – hCaM-2 + NADPH oxidase peptide<br />
**[[2lgf]] – hCaM + selectin peptide<br />
**[[2lgf]] – hCaM + selectin peptide<br />
**[[2fot]] - bCaM+α-II spectrin CBD<br />
**[[2fot]] - bCaM+α-II spectrin CBD<br />
Line 117: Line 127:
**[[1g4y]], [[3sjq]], [[4g27]], [[4g28]], [[4qnh]] - rCaM+ potassium channel CBD<br />
**[[1g4y]], [[3sjq]], [[4g27]], [[4g28]], [[4qnh]] - rCaM+ potassium channel CBD<br />
**[[2ygg]] – rCaM + Na/H exchanger CBD<br />
**[[2ygg]] – rCaM + Na/H exchanger CBD<br />
 +
**[[7nqc]] – rCaM + peptide - NMR<br />
**[[2mgu]] – rCaM + HIV-1 matrix protein CBD – NMR<br />
**[[2mgu]] – rCaM + HIV-1 matrix protein CBD – NMR<br />
**[[1qx7]] – rCaM+potassium channel peptide<br />
**[[1qx7]] – rCaM+potassium channel peptide<br />
Line 150: Line 161:
**[[2bki]], [[2bkh]] – pCaM + myosin VI – pig<br />
**[[2bki]], [[2bkh]] – pCaM + myosin VI – pig<br />
**[[4zlk]] – mCaM + myosin VA<br />
**[[4zlk]] – mCaM + myosin VA<br />
 +
**[[8of8]] – mCaM + actin + myosin VA – Cryo EM<br />
**[[2ix7]] – mCaM + myosin-5A<br />
**[[2ix7]] – mCaM + myosin-5A<br />
 +
**[[7yv9]] – mCaM + myosin VI – Cryo EM<br />
**[[4r8g]] – rCaM + myosin 1B<br />
**[[4r8g]] – rCaM + myosin 1B<br />
**[[3ek4]], [[3ek7]], [[3ek8]], [[3ekh]], [[3ekj]], [[3evr]], [[3evu]], [[3evv]], [[3o77]], [[3o78]] – rCaM/DFP/myosin light chain kinase<br />
**[[3ek4]], [[3ek7]], [[3ek8]], [[3ekh]], [[3ekj]], [[3evr]], [[3evu]], [[3evv]], [[3o77]], [[3o78]] – rCaM/DFP/myosin light chain kinase<br />
 +
**[[2dfs]] – cCaM + myosin 5A<br />
 +
**[[6bnv]] – cCaM + myosin 6 + actin - Cryo EM<br />
**[[2vas]], [[2vb6]], [[3gn4]], [[3l9i]], [[4dbp]], [[4dbq]], [[2x51]], [[4anj]] – DmCaM + pMyosin IV<br />
**[[2vas]], [[2vb6]], [[3gn4]], [[3l9i]], [[4dbp]], [[4dbq]], [[2x51]], [[4anj]] – DmCaM + pMyosin IV<br />
**[[4pjj]] - DmCaM + pMyosin VI<br />
**[[4pjj]] - DmCaM + pMyosin VI<br />
-
**[[2dfs]] – cCaM + myosin 5A<br />
+
**[[6ui4]] - CaM + Myosin I + fungicide – ''Fusarium graminearum''<br />
-
**[[6bnv]] – cCaM + myosin 6 + actin<br />
+
*Calmodulin complex with ion channels
*Calmodulin complex with ion channels
Line 163: Line 177:
**[[4dck]], [[4jpz]] - hCaM + sodium channel protein type V α subunit + fibroblast growth factor 13<br />
**[[4dck]], [[4jpz]] - hCaM + sodium channel protein type V α subunit + fibroblast growth factor 13<br />
**[[4jq0]] - hCaM + sodium channel protein type V α subunit + fibroblast growth factor 12<br />
**[[4jq0]] - hCaM + sodium channel protein type V α subunit + fibroblast growth factor 12<br />
-
**[[5k7l]] - hCaM + potassium channel EAG1 – Cryo EM <br />
+
**[[5k7l]], [[6pbx]], [[6pby]], [[8eow]], [[8ep0]], [[8ep1]] - hCaM + potassium channel EAG1 – Cryo EM <br />
**[[5j03]], [[6feh]], [[6feg]], [[6b8q]], [[6b8p]], [[6b8n]], [[6b8m]], [[6b8l]], [[5vms]] - hCaM + potassium channel subfamily KQT <br />
**[[5j03]], [[6feh]], [[6feg]], [[6b8q]], [[6b8p]], [[6b8n]], [[6b8m]], [[6b8l]], [[5vms]] - hCaM + potassium channel subfamily KQT <br />
 +
**[[6uzz]], [[7tcp]], [[7xni]], [[8sik]], [[8sim]], [[8sin]] – hCaM-1+ potassium channel subfamily KQT – Cryo EM<br />
 +
**[[7xnl]], [[7xnn]], [[8ijk]], [[8j01]], [[8j02]], [[8j03]], [[8j04]], [[8j05]], [[8w4u]], [[8x43]] – hCaM-1+ potassium channel subfamily KQT + ligand – Cryo EM<br />
 +
**[[8j00]] – hCaM-1+ potassium channel subfamily KQT + cannabidiol – Cryo EM<br />
 +
**[[7xnk]] – hCaM-1+ potassium channel subfamily KQT + enhancer – Cryo EM<br />
 +
**[[9cui]], [[9cuk]] – hCaM-1+ calcium channel TRPV6 – Cryo EM<br />
 +
**[[8bx7]], [[8dgh]], [[8dgk]] – hCaM-1+ CNG channel peptide – NMR<br />
 +
**[[7byl]] – hCaM-3 + potassium channel subfamily KQT – Cryo EM<br />
 +
**[[7bym]], [[7byn]], [[7vnr]] – hCaM-3 + potassium channel subfamily KQT + drug – Cryo EM<br />
 +
**[[7vnp]], [[7vnq]] – hCaM-3 + potassium channel subfamily KQT + PTDINS – Cryo EM<br />
 +
**[[6v00]], [[6v01]] – hCaM-1 + potassium channel subfamily KQT + KCNE3 – Cryo EM<br />
 +
**[[7tci]] – hCaM-1 + potassium channel subfamily KQT + piperidine derivative – Cryo EM<br />
 +
**[[7cr3]] – hCaM-3 + potassium channel subfamily KQT – Cryo EM<br />
 +
**[[7cr4]], [[7cr7]] – hCaM-3 + potassium channel subfamily KQT + drug – Cryo EM<br />
**[[5wc5]], [[5wbx]], [[5v03]], [[5v02]], [[6czq]] – hCaM + potassium channel KCAT2.2 <br />
**[[5wc5]], [[5wbx]], [[5v03]], [[5v02]], [[6czq]] – hCaM + potassium channel KCAT2.2 <br />
**[[6cnm]], [[6cnn]], [[6cno]] – hCaM + potassium channel Sk4 <br />
**[[6cnm]], [[6cnn]], [[6cno]] – hCaM + potassium channel Sk4 <br />
-
**[[6ale]] – hCaM + potassium channel Sk2 <br />
+
**[[6ale]] – hCaM-2 + potassium channel Sk2 <br />
-
**[[6n5w]] – hCaM + potassium channel Kv7.4 <br />
+
**[[7vuo]], [[7vvd]], [[7vvh]] – hCaM-1 (mutant) + potassium channel Kv7.1 C terminal <br />
 +
**[[6n5w]] – hCaM-1 + potassium channel Kv7.4 <br />
**[[6e2f]], [[6e2g]], [[6dmw]] – hCaM + transient receptor potential cation channel – Cryo EM <br />
**[[6e2f]], [[6e2g]], [[6dmw]] – hCaM + transient receptor potential cation channel – Cryo EM <br />
**[[5oeo]] – hCaM + transient receptor potential cation channel – NMR <br />
**[[5oeo]] – hCaM + transient receptor potential cation channel – NMR <br />
-
**[[6dad]], [[6dae]], [[6daf]] - hCaM (mutant) + calcium channel Cav1.2 <br />
+
**[[6ctb]] - hCaM + calcium channel Cav1.2 - NMR<br />
 +
**[[6but]] – hCaM-1 + IQ motif of NaV1.2<br />
 +
**[[6u3a]] – hCaM-1 (mutant) + IQ motif of NaV1.2<br />
 +
**[[6mue]] – hCaM-1 + IQ motif of NaV1.4<br />
 +
**[[6mud]] – hCaM-1 + IQ motif of NaV1.5<br />
 +
**[[6dad]], [[6dae]], [[6daf]], [[6u39]], [[6u3b]], [[6u3d]] - hCaM (mutant) + calcium channel Cav1.2 <br />
 +
**[[6o20]] – bCaM + calcium channel TRPV5 – Cryo EM <br />
**[[6mba]], [[6mc9]] - rCaM + sodium channel protein type IV α subunit<br />
**[[6mba]], [[6mc9]] - rCaM + sodium channel protein type IV α subunit<br />
Line 180: Line 214:
**[[4q57]] – hCaM N-terminal + plectin<br />
**[[4q57]] – hCaM N-terminal + plectin<br />
**[[4q5u]] – hCaM + calcineurin<br />
**[[4q5u]] – hCaM + calcineurin<br />
-
**[[2x0g]] – hCaM + death-associated protein kinase 1 (DAP)<br />
+
**[[2x0g]] – hCaM + death-associated protein kinase 1<br />
 +
**[[6paw]] – hCaM-1 + death-associated protein kinase 2<br />
 +
**[[6k4k]], [[6k4l]] – hCaM-1 + SidJ <br />
 +
**[[7ppo]], [[7pqe]] – hCaM-1 + SidJ + SdeA – Cryo EM<br />
 +
**[[6k4r]] – hCaM-1 + SidJ + AMP<br />
 +
**[[7sx3]], [[7sx4]], [[7wji]] – hCaM-1 in channelosome – Cryo EM<br />
 +
**[[7xn4]] – hCaM-1 + caspase-3 + CopC + NAD – Cryo EM<br />
 +
**[[7xn5]], [[7xn6]] – hCaM-1 + caspase-3 + CopC + ADPR – Cryo EM<br />
 +
**[[7wzs]] – hCaM-1 + caspase-7 + CopC <br />
 +
**[[7wr4]], [[7wr5]] – hCaM-1 + caspase-4 + OspC3 + NAD – Cryo EM<br />
 +
**[[7wr3]] – hCaM-1 + OspC3 <br />
 +
**[[8jfk]], [[8xya]], [[8xyb]] – hCaM-1 + phosphorylase B kinase + farnesyl – Cryo EM<br />
 +
**[[8fo6]] – hCaM-1 + EEF-2 kinase <br />
 +
**[[8gn4]] – hCaM-1 + EEF-2 kinase – Cryo EM<br />
 +
**[[8fny]] – hCaM-1 + EEF-2 kinase + ADP + ATP<br />
 +
**[[8gm5]] – hCaM-1 + EEF-2 kinase + ADP + inhibitor<br />
 +
**[[7vmb]] – hCaM-1 + IQSEC1<br />
 +
**[[6oqq]] – hCaM-2 + SidJ – Cryo EM<br />
 +
**[[6plm]] – hCaM-2 + SidJ + AMP<br />
 +
**[[7mir]], [[7mis]] – hCaM-2 + SidJ + SdeA + AMP + ATP – Cryo EM<br />
 +
**[[6pjx]] – hCaM + GRK5 <br />
 +
**[[7b1g]] – hCaM + TRPC4 <br />
 +
**[[7cqp]] – hCaM + TRPC4 peptide<br />
 +
**[[7wzs]] – hCaM + caspase + CopC <br />
 +
**[[6yns]], [[6ynu]] – hCaM + P458 <br />
 +
**[[8ahs]] – hCaM + melittin <br />
 +
**[[6o20]] – bCaM + TRPV5 – Cryo EM <br />
**[[2k3s]] – XlCaM + smoothelin-like protein 1 – NMR<br />
**[[2k3s]] – XlCaM + smoothelin-like protein 1 – NMR<br />
**[[5sy1]] – faCaM + STRA6 <br />
**[[5sy1]] – faCaM + STRA6 <br />
 +
**[[6xwv]] – DmCaM + ryanodine receptor <br />
 +
**[[6s5t]] – yCaM + SidJ <br />
**[[1qs7]], [[1qtx]] – EcCaM + RS20 – ''Escherichia coli''<br />
**[[1qs7]], [[1qtx]] – EcCaM + RS20 – ''Escherichia coli''<br />
**[[1vrk]] – EcCaM (mutant) + RS20<br />
**[[1vrk]] – EcCaM (mutant) + RS20<br />
Line 189: Line 251:
**[[1zot]] – BpCaM C-terminal+ adenyl cyclase<br />
**[[1zot]] – BpCaM C-terminal+ adenyl cyclase<br />
**[[1xfu]], [[1xfv]], [[1xfw]], [[1xfx]], [[1xfy]], [[1xfz]], [[1y0v]], [[1sk6]], [[1pk0]], [[1lvc]], [[1k90]], [[1k93]] - CaM + adenyl cyclase – ''Bacillus anthracis''<br />
**[[1xfu]], [[1xfv]], [[1xfw]], [[1xfx]], [[1xfy]], [[1xfz]], [[1y0v]], [[1sk6]], [[1pk0]], [[1lvc]], [[1k90]], [[1k93]] - CaM + adenyl cyclase – ''Bacillus anthracis''<br />
 +
**[[7jts]] – CrCaM + Dynein + FAP207 + FAP253 + radial spoke protein 3 – ''Chlamydomonas renhardtii'' – Cryo EM<br />
 +
**[[8bwy]] – CrCaM in dynein arm complex – Cryo EM<br />
 +
**[[8aht]] – CaM + melittin – ''Plasmodium falciparum''<br />
 +
**[[8th8]] – CaM-7-2 in nexin-dynein complex – ''Tetrahymena thermophila'' – Cryo EM<br />
 +
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D Structures of Calmodulin

Updated on 29-December-2024

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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