1v0n

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[[Image:1v0n.jpg|left|200px]]
[[Image:1v0n.jpg|left|200px]]
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{{Structure
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<!--
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|PDB= 1v0n |SIZE=350|CAPTION= <scene name='initialview01'>1v0n</scene>, resolution 1.10&Aring;
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The line below this paragraph, containing "STRUCTURE_1v0n", creates the "Structure Box" on the page.
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|SITE= <scene name='pdbsite=AC1:Catalytic+Nucleophile'>AC1</scene>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=XIF:PIPERIDINE-3,4-DIOL'>XIF</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_1v0n| PDB=1v0n | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v0n OCA], [http://www.ebi.ac.uk/pdbsum/1v0n PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1v0n RCSB]</span>
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}}
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'''XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-ISOFAGOMINE AT PH 7.5'''
'''XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-ISOFAGOMINE AT PH 7.5'''
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[[Category: Williams, S J.]]
[[Category: Williams, S J.]]
[[Category: Withers, S G.]]
[[Category: Withers, S G.]]
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[[Category: deoxynojirimycin]]
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[[Category: Deoxynojirimycin]]
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[[Category: glycoside hydrolase family 10]]
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[[Category: Glycoside hydrolase family 10]]
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[[Category: hydrolase]]
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[[Category: Hydrolase]]
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[[Category: xylan degradation]]
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[[Category: Xylan degradation]]
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[[Category: xylanase]]
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[[Category: Xylanase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 11:56:37 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:17:55 2008''
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Revision as of 08:56, 3 May 2008

Image:1v0n.jpg

Template:STRUCTURE 1v0n

XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-ISOFAGOMINE AT PH 7.5


Overview

The atomic resolution structures of xylobiose-derived isofagomine and xylobiose-derived deoxynojirimycin in complex with the xylanase Xyn10A from Streptomyces lividans reveal undistorted (4)C(1) chair conformed sugars and, in the case of the deoxynojirimycin analogue, suggest unusual pK(a) changes of the enzyme's catalytic machinery upon binding.

About this Structure

1V0N is a Single protein structure of sequence from Streptomyces lividans. Full crystallographic information is available from OCA.

Reference

Atomic resolution analyses of the binding of xylobiose-derived deoxynojirimycin and isofagomine to xylanase Xyn10A., Gloster TM, Williams SJ, Roberts S, Tarling CA, Wicki J, Withers SG, Davies GJ, Chem Commun (Camb). 2004 Aug 21;(16):1794-5. Epub 2004 Jul 23. PMID:15306887 Page seeded by OCA on Sat May 3 11:56:37 2008

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