User:Karsten Theis/Trypsin

Figure 1:

Figure 2:

with

Figure 3: active site and oxyanion hole

Figure 4:

Figure 5: inhibitor complex

^[1]

^[2]

Further reading

https://www.worthington-biochem.com/products/trypsin/manual (alpha trypsin, beta, anionic, cationic...)

anhydro: treated to convert serines to anhydroalanines

https://www.elegantexperiments.net/en/post/length-digestive-system/ digestive tract length

https://derangedphysiology.com/main/cicm-primary-exam/gastrointestinal-system/Chapter-110/composition-volumes-and-regulation-gastrointestinal-secretions volume of secretions

https://pubmed.ncbi.nlm.nih.gov/24694282/ Surface area (tennis court or badminton court?)

References

1. ↑ Bode W, Walter J, Huber R, Wenzel HR, Tschesche H. The refined 2.2-A (0.22-nm) X-ray crystal structure of the ternary complex formed by bovine trypsinogen, valine-valine and the Arg15 analogue of bovine pancreatic trypsin inhibitor. Eur J Biochem. 1984 Oct 1;144(1):185-90. PMID:6207021
2. ↑ Bode W, Huber R. Induction of the bovine trypsinogen-trypsin transition by peptides sequentially similar to the N-terminus of trypsin. FEBS Lett. 1976 Oct 1;68(2):231-6. PMID:10181 doi:10.1016/0014-5793(76)80443-7