1t8h

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[[Image:1t8h.png|left|200px]]
 
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{{STRUCTURE_1t8h| PDB=1t8h | SCENE= }}
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==1.8 A CRYSTAL STRUCTURE OF AN UNCHARACTERIZED B. STEAROTHERMOPHILUS PROTEIN==
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<StructureSection load='1t8h' size='340' side='right'caption='[[1t8h]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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===1.8 A CRYSTAL STRUCTURE OF AN UNCHARACTERIZED B. STEAROTHERMOPHILUS PROTEIN===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1t8h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T8H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T8H FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[1t8h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T8H OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t8h OCA], [https://pdbe.org/1t8h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t8h RCSB], [https://www.ebi.ac.uk/pdbsum/1t8h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t8h ProSAT], [https://www.topsan.org/Proteins/MCSG/1t8h TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PURNU_GEOS3 PURNU_GEOS3] Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine (PubMed:31978345). Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate (PubMed:31978345). Also has adenosine deaminase activity (PubMed:31978345).<ref>PMID:31978345</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t8/1t8h_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t8h ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
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[[Category: Anderson, W F.]]
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[[Category: Large Structures]]
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[[Category: Collart, F R.]]
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[[Category: Anderson WF]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Collart FR]]
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[[Category: Minasov, G.]]
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[[Category: Minasov G]]
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[[Category: Mondragon, A.]]
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[[Category: Mondragon A]]
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[[Category: Moy, S F.]]
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[[Category: Moy SF]]
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[[Category: Shuvalova, L.]]
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[[Category: Shuvalova L]]
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[[Category: Taneja, B.]]
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[[Category: Taneja B]]
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[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Rbstp0554]]
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[[Category: Structural genomic]]
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[[Category: Unknown function]]
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Current revision

1.8 A CRYSTAL STRUCTURE OF AN UNCHARACTERIZED B. STEAROTHERMOPHILUS PROTEIN

PDB ID 1t8h

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